6tgh - Revision history

OCA at 13:01, 24 January 2024

OCA — Wed, 24 Jan 2024 13:01:55 GMT

←Older revision		Revision as of 13:01, 24 January 2024
Line 1:		Line 1:

-	==SHMT from Streptococcus thermophilus Tyr55Thr variant in complex with D-Serine both as external aldimine and as non-covalent complex==	+	==SHMT from Streptococcus thermophilus Tyr55Thr variant in complex with D-Serine both as external aldimine and as non-covalent complex==
-	<StructureSection load='6tgh' size='340' side='right'caption='[[6tgh]]' scene=''>	+	<StructureSection load='6tgh' size='340' side='right'caption='[[6tgh]], [[Resolution\|resolution]] 2.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TGH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TGH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6tgh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_thermophilus Streptococcus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TGH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TGH FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tgh OCA], [https://pdbe.org/6tgh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tgh RCSB], [https://www.ebi.ac.uk/pdbsum/6tgh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tgh ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.12Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DSN:D-SERINE'>DSN</scene>, <scene name='pdbligand=EVM:L-Serine,+N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methylene]'>EVM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tgh OCA], [https://pdbe.org/6tgh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tgh RCSB], [https://www.ebi.ac.uk/pdbsum/6tgh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tgh ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/GLYA_STRT1 GLYA_STRT1] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

	==See Also==		==See Also==
-	*[[Serine hydroxymethyltransferase\|Serine hydroxymethyltransferase]]	+	*[[Serine hydroxymethyltransferase 3D structures\|Serine hydroxymethyltransferase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Petrillo, G, Hernandez, K,~~ Bujons, J, Clapes, P, Uson, I]]	+	[[Category: Streptococcus thermophilus]]
		+	[[Category: Bujons J]]
		+	[[Category: Clapes P]]
		+	[[Category: Hernandez K]]
		+	[[Category: Petrillo G]]
		+	[[Category: Uson I]]

OCA at 15:18, 8 June 2021

OCA — Tue, 08 Jun 2021 15:18:49 GMT

←Older revision		Revision as of 15:18, 8 June 2021
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	<StructureSection load='6tgh' size='340' side='right'caption='[[6tgh]]' scene=''>		<StructureSection load='6tgh' size='340' side='right'caption='[[6tgh]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TGH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6TGH FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TGH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TGH FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6tgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tgh OCA], [~~http~~://pdbe.org/6tgh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6tgh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6tgh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6tgh ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tgh OCA], [https://pdbe.org/6tgh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tgh RCSB], [https://www.ebi.ac.uk/pdbsum/6tgh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tgh ProSAT]</span></td></tr>
	</table>		</table>
		+
		+	==See Also==
		+	*[[Serine hydroxymethyltransferase\|Serine hydroxymethyltransferase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Petrillo, G, Hernandez, K, Bujons, J, Clapes, P, Uson, I]]		[[Category: Petrillo, G, Hernandez, K, Bujons, J, Clapes, P, Uson, I]]

OCA at 06:28, 3 June 2020

OCA — Wed, 03 Jun 2020 06:28:05 GMT

←Older revision		Revision as of 06:28, 3 June 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6tgh is ON HOLD~~	+	==SHMT from Streptococcus thermophilus Tyr55Thr variant in complex with D-Serine both as external aldimine and as non-covalent complex==
-		+	<StructureSection load='6tgh' size='340' side='right'caption='[[6tgh]]' scene=''>
-	~~Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TGH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TGH FirstGlance]. <br>
-	~~Description:~~ SHMT from Streptococcus thermophilus Tyr55Thr variant in complex with D-Serine both as external aldimine and as non-covalent complex	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tgh OCA], [http://pdbe.org/6tgh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tgh RCSB], [http://www.ebi.ac.uk/pdbsum/6tgh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tgh ProSAT]</span></td></tr>
-	[[~~Category: Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Hernandez, K]~~]	+	__TOC__
-	[[~~Category~~: ~~Petrillo~~, G]]	+	</StructureSection>
-	[[~~Category~~: ~~Bujons~~, J]]	+	[[Category: Large Structures]]
-	[[Category: ~~Uson, I~~]]	+	[[Category: Petrillo, G, Hernandez, K, Bujons, J, Clapes, P, Uson, I]]
-	[[Category: Clapes, P]]	+

OCA at 08:23, 18 March 2020

OCA — Wed, 18 Mar 2020 08:23:44 GMT

←Older revision		Revision as of 08:23, 18 March 2020
Line 5:		Line 5:
	Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I.		Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I.

-	Description: ~~SHMTSth~~ Tyr55Thr in complex with D-~~Ser~~ both as external aldimine and as non-covalent complex	+	Description: SHMT from Streptococcus thermophilus Tyr55Thr variant in complex with D-Serine both as external aldimine and as non-covalent complex
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Hernandez, K]]
	[[Category: Petrillo, G]]		[[Category: Petrillo, G]]
	[[Category: Bujons, J]]		[[Category: Bujons, J]]
	[[Category: Uson, I]]		[[Category: Uson, I]]
-	[[Category: Hernandez, K]]
	[[Category: Clapes, P]]		[[Category: Clapes, P]]

OCA: Protected "6tgh" [edit=sysop:move=sysop]

OCA — Wed, 27 Nov 2019 05:14:38 GMT

Protected "6tgh" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:14, 27 November 2019

OCA: New page: '''Unreleased structure''' The entry 6tgh is ON HOLD Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I. Description: SHMTSth Tyr55Thr in complex with D-Ser both as ...

OCA — Wed, 27 Nov 2019 05:14:36 GMT

New page: '''Unreleased structure''' The entry 6tgh is ON HOLD Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I. Description: SHMTSth Tyr55Thr in complex with D-Ser both as ...

New page

'''Unreleased structure'''

The entry 6tgh is ON HOLD

Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I.

Description: SHMTSth Tyr55Thr in complex with D-Ser both as external aldimine and as non-covalent complex
[[Category: Unreleased Structures]]
[[Category: Petrillo, G]]
[[Category: Bujons, J]]
[[Category: Uson, I]]
[[Category: Hernandez, K]]
[[Category: Clapes, P]]