6ti3 - Revision history

OCA at 13:02, 24 January 2024

OCA — Wed, 24 Jan 2024 13:02:43 GMT

←Older revision		Revision as of 13:02, 24 January 2024
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	==Apo-SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with D-Threonine==		==Apo-SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with D-Threonine==
-	<StructureSection load='6ti3' size='340' side='right'caption='[[6ti3]]' scene=''>	+	<StructureSection load='6ti3' size='340' side='right'caption='[[6ti3]], [[Resolution\|resolution]] 1.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TI3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6TI3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ti3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_thermophilus Streptococcus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TI3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6ti3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ti3 OCA], [~~http~~://pdbe.org/6ti3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ti3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ti3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ti3 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.96Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTH:D-THREONINE'>DTH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ti3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ti3 OCA], [https://pdbe.org/6ti3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ti3 RCSB], [https://www.ebi.ac.uk/pdbsum/6ti3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ti3 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/GLYA_STRT1 GLYA_STRT1] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
		+
		+	==See Also==
		+	*[[Serine hydroxymethyltransferase 3D structures\|Serine hydroxymethyltransferase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Streptococcus thermophilus]]
	[[Category: Bujons J]]		[[Category: Bujons J]]
	[[Category: Clapes P]]		[[Category: Clapes P]]

OCA at 06:45, 29 April 2020

OCA — Wed, 29 Apr 2020 06:45:40 GMT

←Older revision		Revision as of 06:45, 29 April 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6ti3 ~~is ON HOLD~~	+	==Apo-SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with D-Threonine==
-		+	<StructureSection load='6ti3' size='340' side='right'caption='[[6ti3]]' scene=''>
-	~~Authors~~: ~~Petrillo~~, G., ~~Hernandez, K~~., ~~Bujons, J~~., ~~Clapes, P~~., ~~Uson, I~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TI3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TI3 FirstGlance]. <br>
-	~~Description: Apo-SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with D-Threonine~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ti3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ti3 OCA], [http://pdbe.org/6ti3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ti3 RCSB], [http://www.ebi.ac.uk/pdbsum/6ti3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ti3 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Hernandez, K~~]]	+	__TOC__
-	[[Category: ~~Petrillo, G~~]]	+	</StructureSection>
-	[[Category: ~~Bujons, J~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Uson, I~~]]	+	[[Category: Bujons J]]
-	[[Category: ~~Clapes, P~~]]	+	[[Category: Clapes P]]
		+	[[Category: Hernandez K]]
		+	[[Category: Petrillo G]]
		+	[[Category: Uson I]]

OCA at 08:23, 18 March 2020

OCA — Wed, 18 Mar 2020 08:23:53 GMT

←Older revision		Revision as of 08:23, 18 March 2020
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	Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I.		Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I.

-	Description: ~~SHMTSth Tyr55Thr~~ in complex with D-~~Ser both as external aldimine and as non-covalent complex~~	+	Description: Apo-SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with D-Threonine
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Hernandez, K]]
	[[Category: Petrillo, G]]		[[Category: Petrillo, G]]
	[[Category: Bujons, J]]		[[Category: Bujons, J]]
	[[Category: Uson, I]]		[[Category: Uson, I]]
-	[[Category: Hernandez, K]]
	[[Category: Clapes, P]]		[[Category: Clapes, P]]

OCA: Protected "6ti3" [edit=sysop:move=sysop]

OCA — Wed, 27 Nov 2019 05:19:18 GMT

Protected "6ti3" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:19, 27 November 2019

OCA: New page: '''Unreleased structure''' The entry 6ti3 is ON HOLD Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I. Description: SHMTSth Tyr55Thr in complex with D-Ser both as ...

OCA — Wed, 27 Nov 2019 05:19:17 GMT

New page: '''Unreleased structure''' The entry 6ti3 is ON HOLD Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I. Description: SHMTSth Tyr55Thr in complex with D-Ser both as ...

New page

'''Unreleased structure'''

The entry 6ti3 is ON HOLD

Authors: Petrillo, G., Hernandez, K., Bujons, J., Clapes, P., Uson, I.

Description: SHMTSth Tyr55Thr in complex with D-Ser both as external aldimine and as non-covalent complex
[[Category: Unreleased Structures]]
[[Category: Petrillo, G]]
[[Category: Bujons, J]]
[[Category: Uson, I]]
[[Category: Hernandez, K]]
[[Category: Clapes, P]]