6tsx - Revision history

OCA at 13:08, 24 January 2024

OCA — Wed, 24 Jan 2024 13:08:41 GMT

←Older revision		Revision as of 13:08, 24 January 2024
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	<StructureSection load='6tsx' size='340' side='right'caption='[[6tsx]], [[Resolution\|resolution]] 2.02Å' scene=''>		<StructureSection load='6tsx' size='340' side='right'caption='[[6tsx]], [[Resolution\|resolution]] 2.02Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6tsx]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TSX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6TSX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6tsx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TSX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:~~FE+~~(~~III~~)~~+ION~~'>FE</scene>, <scene name='pdbligand=O:~~OXYGEN~~+~~ATOM~~'>O</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.021Å</td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~CME~~:~~S,S-(2-HYDROXYETHYL)THIOCYSTEINE~~'>~~CME~~</scene>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6tsj\|6tsj]], [[6tsa\|6tsa]], [[6tsf\|6tsf]], [[6tr9\|6tr9]], [[6ts0\|6ts0]], [[6ts1\|6ts1]], [[6trz\|6trz]], [[6tss\|6tss]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tsx OCA], [https://pdbe.org/6tsx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tsx RCSB], [https://www.ebi.ac.uk/pdbsum/6tsx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tsx ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6tsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tsx OCA], [~~http~~://pdbe.org/6tsx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6tsx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6tsx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6tsx ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/FRIL_HORSE FRIL_HORSE]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).	+	[https://www.uniprot.org/uniprot/FRIL_HORSE FRIL_HORSE] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6tsx" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6tsx" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ferritin 3D structures\|Ferritin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Equus caballus]]		[[Category: Equus caballus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ciambellotti, S]]	+	[[Category: Ciambellotti S]]
-	[[Category: Mangani, S]]	+	[[Category: Mangani S]]
-	[[Category: Pozzi, C]]	+	[[Category: Pozzi C]]
-	[[Category: Turano, P]]	+	[[Category: Turano P]]
-	~~[[Category: Holf]]~~	+
-	~~[[Category: Horse l ferritin]]~~	+
-	~~[[Category: Metal binding protein~~]]	+

OCA at 06:08, 20 May 2020

OCA — Wed, 20 May 2020 06:08:21 GMT

←Older revision		Revision as of 06:08, 20 May 2020
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	<StructureSection load='6tsx' size='340' side='right'caption='[[6tsx]], [[Resolution\|resolution]] 2.02Å' scene=''>		<StructureSection load='6tsx' size='340' side='right'caption='[[6tsx]], [[Resolution\|resolution]] 2.02Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6tsx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TSX OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6TSX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6tsx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TSX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TSX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6tsj\|6tsj]], [[6tsa\|6tsa]], [[6tsf\|6tsf]], [[6tr9\|6tr9]], [[6ts0\|6ts0]], [[6ts1\|6ts1]], [[6trz\|6trz]], [[6tss\|6tss]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6tsj\|6tsj]], [[6tsa\|6tsa]], [[6tsf\|6tsf]], [[6tr9\|6tr9]], [[6ts0\|6ts0]], [[6ts1\|6ts1]], [[6trz\|6trz]], [[6tss\|6tss]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6tsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tsx OCA], [http://pdbe.org/6tsx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tsx RCSB], [http://www.ebi.ac.uk/pdbsum/6tsx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tsx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tsx OCA], [http://pdbe.org/6tsx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tsx RCSB], [http://www.ebi.ac.uk/pdbsum/6tsx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tsx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 06:39, 19 February 2020

OCA — Wed, 19 Feb 2020 06:39:53 GMT

←Older revision		Revision as of 06:39, 19 February 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6tsx is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of horse L ferritin (HoLf) Fe(III)-loaded for 30 minutes==
		+	<StructureSection load='6tsx' size='340' side='right'caption='[[6tsx]], [[Resolution\|resolution]] 2.02Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6tsx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TSX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TSX FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6tsj\|6tsj]], [[6tsa\|6tsa]], [[6tsf\|6tsf]], [[6tr9\|6tr9]], [[6ts0\|6ts0]], [[6ts1\|6ts1]], [[6trz\|6trz]], [[6tss\|6tss]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tsx OCA], [http://pdbe.org/6tsx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tsx RCSB], [http://www.ebi.ac.uk/pdbsum/6tsx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tsx ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FRIL_HORSE FRIL_HORSE]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	X-ray structures of homopolymeric human L-ferritin and horse spleen ferritin were solved by freezing protein crystals at different time intervals after exposure to a ferric salt and revealed the growth of an octa-nuclear iron cluster on the inner surface of the protein cage with a key role played by some glutamate residues. An atomic resolution view of how the cluster formation develops starting from a (mu 3 -oxo)tris[(mu 2 -glutamato-kappaO:kappaO')](glutamato-kappaO)(diaquo)triiron(III) seed is provided. The results support the idea that iron biomineralization in ferritin is a process initiating at the level of the protein surface, capable of contributing coordination bonds and electrostatic guidance.

-	~~Authors: Pozzi, C~~., Ciambellotti, S., Turano, P.~~, Mangani, S~~.	+	Iron biomineral growth from the initial nucleation seed in L-ferritin.,Ciambellotti S, Pozzi C, Mangani S, Turano P Chemistry. 2020 Feb 6. doi: 10.1002/chem.202000064. PMID:32027764<ref>PMID:32027764</ref>

-	~~Description: Crystal structure~~ of ~~horse L ferritin (HoLf) Fe(III)~~-~~loaded for 30 minutes~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
-	[[Category: ~~Mangani, S~~]]	+	<div class="pdbe-citations 6tsx" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Equus caballus]]
		+	[[Category: Large Structures]]
	[[Category: Ciambellotti, S]]		[[Category: Ciambellotti, S]]
-	[[Category: ~~Turano~~, P]]	+	[[Category: Mangani, S]]
	[[Category: Pozzi, C]]		[[Category: Pozzi, C]]
		+	[[Category: Turano, P]]
		+	[[Category: Holf]]
		+	[[Category: Horse l ferritin]]
		+	[[Category: Metal binding protein]]

OCA at 06:02, 8 January 2020

OCA — Wed, 08 Jan 2020 06:02:08 GMT

←Older revision		Revision as of 06:02, 8 January 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6tsx is ON HOLD	+	The entry 6tsx is ON HOLD until Paper Publication

	Authors: Pozzi, C., Ciambellotti, S., Turano, P., Mangani, S.		Authors: Pozzi, C., Ciambellotti, S., Turano, P., Mangani, S.

OCA: Protected "6tsx" [edit=sysop:move=sysop]

OCA — Wed, 01 Jan 2020 06:45:14 GMT

Protected "6tsx" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:45, 1 January 2020

OCA: New page: '''Unreleased structure''' The entry 6tsx is ON HOLD Authors: Pozzi, C., Ciambellotti, S., Turano, P., Mangani, S. Description: Crystal structure of horse L ferritin (HoLf) Fe(III)-loa...

OCA — Wed, 01 Jan 2020 06:45:13 GMT

New page: '''Unreleased structure''' The entry 6tsx is ON HOLD Authors: Pozzi, C., Ciambellotti, S., Turano, P., Mangani, S. Description: Crystal structure of horse L ferritin (HoLf) Fe(III)-loa...

New page

'''Unreleased structure'''

The entry 6tsx is ON HOLD

Authors: Pozzi, C., Ciambellotti, S., Turano, P., Mangani, S.

Description: Crystal structure of horse L ferritin (HoLf) Fe(III)-loaded for 30 minutes
[[Category: Unreleased Structures]]
[[Category: Mangani, S]]
[[Category: Ciambellotti, S]]
[[Category: Turano, P]]
[[Category: Pozzi, C]]