6ttj - Revision history

OCA at 13:09, 24 January 2024

OCA — Wed, 24 Jan 2024 13:09:02 GMT

←Older revision		Revision as of 13:09, 24 January 2024
Line 3:		Line 3:
	<StructureSection load='6ttj' size='340' side='right'caption='[[6ttj]], [[Resolution\|resolution]] 3.39Å' scene=''>		<StructureSection load='6ttj' size='340' side='right'caption='[[6ttj]], [[Resolution\|resolution]] 3.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ttj]] is a 12 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Arath Arath~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TTJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6TTJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ttj]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TTJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TTJ FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[6sgq\|6sgq]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.392Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">CINV1, INVG, At1g35580, F15O4~~.~~33 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=3702 ARATH])</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ttj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ttj OCA], [https://pdbe.org/6ttj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ttj RCSB], [https://www.ebi.ac.uk/pdbsum/6ttj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ttj ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-fructofuranosidase Beta-fructofuranosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.26 3.2.1.26] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ttj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ttj OCA], [~~http~~://pdbe.org/6ttj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ttj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ttj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ttj ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CINV1_ARATH CINV1_ARATH]] Cytosolic invertase that specifically cleaves sucrose into glucose and fructose and is involved in the regulation of multiple tissue development including primary root elongation, root hair growth, leaf and silique development, and floral transition. Is involved in osmotic stress-induced inhibition on lateral root growth by controlling the concentration of hexose in cells. May regulate sugar-mediated root development by controlling sucrose catabolism in root cells.<ref>PMID:17220200</ref> <ref>PMID:17508130</ref> <ref>PMID:19470642</ref> <ref>PMID:21441406</ref>	+	[https://www.uniprot.org/uniprot/CINV1_ARATH CINV1_ARATH] Cytosolic invertase that specifically cleaves sucrose into glucose and fructose and is involved in the regulation of multiple tissue development including primary root elongation, root hair growth, leaf and silique development, and floral transition. Is involved in osmotic stress-induced inhibition on lateral root growth by controlling the concentration of hexose in cells. May regulate sugar-mediated root development by controlling sucrose catabolism in root cells.<ref>PMID:17220200</ref> <ref>PMID:17508130</ref> <ref>PMID:19470642</ref> <ref>PMID:21441406</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 6ttj" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6ttj" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Invertase\|Invertase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath]]~~	+	[[Category: Arabidopsis thaliana]]
-	~~[[Category: Beta-fructofuranosidase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Beelen, S]]	+	[[Category: Beelen S]]
-	[[Category: Osipov~~, E M~~]]	+	[[Category: Osipov EM]]
-	[[Category: Strelkov~~, S V~~]]	+	[[Category: Strelkov SV]]
-	[[Category: Tsirkone~~, V G]]~~	+	[[Category: Tsirkone VG]]
-	~~[[Category: Carbohydrate]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Invertase~~]]	+

OCA at 10:29, 18 March 2020

OCA — Wed, 18 Mar 2020 10:29:04 GMT

←Older revision		Revision as of 10:29, 18 March 2020
Line 3:		Line 3:
	<StructureSection load='6ttj' size='340' side='right'caption='[[6ttj]], [[Resolution\|resolution]] 3.39Å' scene=''>		<StructureSection load='6ttj' size='340' side='right'caption='[[6ttj]], [[Resolution\|resolution]] 3.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ttj]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TTJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ttj]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TTJ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6sgq\|6sgq]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6sgq\|6sgq]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CINV1, INVG, At1g35580, F15O4.33 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-fructofuranosidase Beta-fructofuranosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.26 3.2.1.26] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-fructofuranosidase Beta-fructofuranosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.26 3.2.1.26] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ttj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ttj OCA], [http://pdbe.org/6ttj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ttj RCSB], [http://www.ebi.ac.uk/pdbsum/6ttj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ttj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ttj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ttj OCA], [http://pdbe.org/6ttj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ttj RCSB], [http://www.ebi.ac.uk/pdbsum/6ttj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ttj ProSAT]</span></td></tr>
Line 10:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/CINV1_ARATH CINV1_ARATH]] Cytosolic invertase that specifically cleaves sucrose into glucose and fructose and is involved in the regulation of multiple tissue development including primary root elongation, root hair growth, leaf and silique development, and floral transition. Is involved in osmotic stress-induced inhibition on lateral root growth by controlling the concentration of hexose in cells. May regulate sugar-mediated root development by controlling sucrose catabolism in root cells.<ref>PMID:17220200</ref> <ref>PMID:17508130</ref> <ref>PMID:19470642</ref> <ref>PMID:21441406</ref>		[[http://www.uniprot.org/uniprot/CINV1_ARATH CINV1_ARATH]] Cytosolic invertase that specifically cleaves sucrose into glucose and fructose and is involved in the regulation of multiple tissue development including primary root elongation, root hair growth, leaf and silique development, and floral transition. Is involved in osmotic stress-induced inhibition on lateral root growth by controlling the concentration of hexose in cells. May regulate sugar-mediated root development by controlling sucrose catabolism in root cells.<ref>PMID:17220200</ref> <ref>PMID:17508130</ref> <ref>PMID:19470642</ref> <ref>PMID:21441406</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The metabolism of sucrose is of crucial importance for life on Earth. In plants, enzymes called invertases split sucrose into glucose and fructose, contributing to the regulation of metabolic fluxes. Invertases differ in their localization and pH optimum. Acidic invertases present in plant cell walls and vacuoles belong to glycoside hydrolase family 32 (GH32) and have an all-beta structure. In contrast, neutral invertases are located in the cytosol and organelles such as chloroplasts and mitochondria. These poorly understood enzymes are classified into a separate GH100 family. Recent crystal structures of the closely related neutral invertases InvA and InvB from the cyanobacterium Anabaena revealed a predominantly alpha-helical fold with unique features compared with other sucrose-metabolizing enzymes. Here, a neutral invertase (AtNIN2) from the model plant Arabidopsis thaliana was heterologously expressed, purified and crystallized. As a result, the first neutral invertase structure from a higher plant has been obtained at 3.4 A resolution. The hexameric AtNIN2 structure is highly similar to that of InvA, pointing to high evolutionary conservation of neutral invertases.
		+
		+	Crystal structure of Arabidopsis thaliana neutral invertase 2.,Tarkowski LP, Tsirkone VG, Osipov EM, Beelen S, Lammens W, Vergauwen R, Van den Ende W, Strelkov SV Acta Crystallogr F Struct Biol Commun. 2020 Mar 1;76(Pt 3):152-157. doi:, 10.1107/S2053230X2000179X. Epub 2020 Mar 3. PMID:32134001<ref>PMID:32134001</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6ttj" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arath]]
	[[Category: Beta-fructofuranosidase]]		[[Category: Beta-fructofuranosidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 07:27, 11 March 2020

OCA — Wed, 11 Mar 2020 07:27:33 GMT

←Older revision		Revision as of 07:27, 11 March 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6ttj is ~~ON HOLD~~	+	==Neutral invertase 2 from Arabidopsis thaliana==
-		+	<StructureSection load='6ttj' size='340' side='right'caption='[[6ttj]], [[Resolution\|resolution]] 3.39Å' scene=''>
-	~~Authors~~: ~~Tsirkone~~, V.G., ~~Osipov, E~~.M., ~~Beelen~~, S., ~~Strelkov~~, S.V.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6ttj]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TTJ FirstGlance]. <br>
-	~~Description: Neutral invertase 2 from Arabidopsis thaliana~~	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6sgq\|6sgq]]</td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-fructofuranosidase Beta-fructofuranosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.26 3.2.1.26] </span></td></tr>
-	[[Category: ~~Tsirkone, V.G~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ttj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ttj OCA], [http://pdbe.org/6ttj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ttj RCSB], [http://www.ebi.ac.uk/pdbsum/6ttj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ttj ProSAT]</span></td></tr>
-	[[Category: ~~Osipov, E.M~~]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CINV1_ARATH CINV1_ARATH]] Cytosolic invertase that specifically cleaves sucrose into glucose and fructose and is involved in the regulation of multiple tissue development including primary root elongation, root hair growth, leaf and silique development, and floral transition. Is involved in osmotic stress-induced inhibition on lateral root growth by controlling the concentration of hexose in cells. May regulate sugar-mediated root development by controlling sucrose catabolism in root cells.<ref>PMID:17220200</ref> <ref>PMID:17508130</ref> <ref>PMID:19470642</ref> <ref>PMID:21441406</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Beta-fructofuranosidase]]
		+	[[Category: Large Structures]]
	[[Category: Beelen, S]]		[[Category: Beelen, S]]
-	[[Category: Strelkov, S.V]]	+	[[Category: Osipov, E M]]
		+	[[Category: Strelkov, S V]]
		+	[[Category: Tsirkone, V G]]
		+	[[Category: Carbohydrate]]
		+	[[Category: Hydrolase]]
		+	[[Category: Invertase]]

OCA: Protected "6ttj" [edit=sysop:move=sysop]

OCA — Wed, 08 Jan 2020 06:03:05 GMT

Protected "6ttj" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:03, 8 January 2020

OCA: New page: '''Unreleased structure''' The entry 6ttj is ON HOLD Authors: Tsirkone, V.G., Osipov, E.M., Beelen, S., Strelkov, S.V. Description: Neutral invertase 2 from Arabidopsis thaliana [[Cate...

OCA — Wed, 08 Jan 2020 06:03:03 GMT

New page: '''Unreleased structure''' The entry 6ttj is ON HOLD Authors: Tsirkone, V.G., Osipov, E.M., Beelen, S., Strelkov, S.V. Description: Neutral invertase 2 from Arabidopsis thaliana [[Cate...

New page

'''Unreleased structure'''

The entry 6ttj is ON HOLD

Authors: Tsirkone, V.G., Osipov, E.M., Beelen, S., Strelkov, S.V.

Description: Neutral invertase 2 from Arabidopsis thaliana
[[Category: Unreleased Structures]]
[[Category: Tsirkone, V.G]]
[[Category: Osipov, E.M]]
[[Category: Beelen, S]]
[[Category: Strelkov, S.V]]