6tup - Revision history

OCA at 10:19, 22 May 2024

OCA — Wed, 22 May 2024 10:19:16 GMT

←Older revision		Revision as of 10:19, 22 May 2024
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	<SX load='6tup' size='340' side='right' viewer='molstar' caption='[[6tup]], [[Resolution\|resolution]] 3.20Å' scene=''>		<SX load='6tup' size='340' side='right' viewer='molstar' caption='[[6tup]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6tup]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa_pao1~~ Pseudomonas aeruginosa ~~pao1~~] and [~~http~~://en.wikipedia.org/wiki/~~Pseudomonas_virus_pf1~~ Pseudomonas virus ~~pf1~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6TUP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6tup]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1] and [https://en.wikipedia.org/wiki/Pseudomonas_virus_Pf1 Pseudomonas virus Pf1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TUP FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6tup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tup OCA], [~~http~~://pdbe.org/6tup PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6tup RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6tup PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6tup ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.2Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tup OCA], [https://pdbe.org/6tup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tup RCSB], [https://www.ebi.ac.uk/pdbsum/6tup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tup ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CAPSD_BPPF1 CAPSD_BPPF1] Self assembles to form a helical capsid wrapping up the viral genomic DNA. The capsid displays a filamentous structure with a length of 760-1950 nm and a width of 6-8 nm. The virion assembly and budding take place at the host inner membrane (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</SX>		</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Pseudomonas aeruginosa ~~pao1~~]]	+	[[Category: Pseudomonas aeruginosa PAO1]]
-	[[Category: Pseudomonas virus ~~pf1~~]]	+	[[Category: Pseudomonas virus Pf1]]
-	[[Category: Bharat~~, T A.M~~]]	+	[[Category: Bharat TAM]]
-	[[Category: ~~Kugelgen, A von~~]]	+	[[Category: Tarafder AK]]
-	[[Category: ~~Tarafder,~~ A ~~K]]~~	+	[[Category: Von Kugelgen A]]
-	~~[[Category: Bacteriophage]]~~	+
-	~~[[Category: Filamentous]]~~	+
-	~~[[Category: Helical]]~~	+
-	~~[[Category: Virus~~]]	+

OCA at 06:34, 11 April 2020

OCA — Sat, 11 Apr 2020 06:34:30 GMT

←Older revision		Revision as of 06:34, 11 April 2020
Line 3:		Line 3:
	<SX load='6tup' size='340' side='right' viewer='molstar' caption='[[6tup]], [[Resolution\|resolution]] 3.20Å' scene=''>		<SX load='6tup' size='340' side='right' viewer='molstar' caption='[[6tup]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6tup]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1] and [http://en.wikipedia.org/wiki/Pseudomonas_virus_pf1 Pseudomonas virus pf1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUP OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6TUP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6tup]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1] and [http://en.wikipedia.org/wiki/Pseudomonas_virus_pf1 Pseudomonas virus pf1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TUP FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6tup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tup OCA], [http://pdbe.org/6tup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tup RCSB], [http://www.ebi.ac.uk/pdbsum/6tup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tup ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tup OCA], [http://pdbe.org/6tup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tup RCSB], [http://www.ebi.ac.uk/pdbsum/6tup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tup ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 6tup" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6tup" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 01:03, 7 March 2020

OCA — Sat, 07 Mar 2020 01:03:12 GMT

←Older revision		Revision as of 01:03, 7 March 2020
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	==Cryo-EM structure of Pf4 bacteriophage coat protein with single-stranded DNA==		==Cryo-EM structure of Pf4 bacteriophage coat protein with single-stranded DNA==
-	<~~StructureSection~~ load='6tup' size='340' side='right'caption='[[6tup]], [[Resolution\|resolution]] 3.20Å' scene=''>	+	<SX load='6tup' size='340' side='right' viewer='molstar' caption='[[6tup]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6tup]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1] and [http://en.wikipedia.org/wiki/Pseudomonas_virus_pf1 Pseudomonas virus pf1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TUP FirstGlance]. <br>		<table><tr><td colspan='2'>[[6tup]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1] and [http://en.wikipedia.org/wiki/Pseudomonas_virus_pf1 Pseudomonas virus pf1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TUP FirstGlance]. <br>
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	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Pseudomonas aeruginosa pao1]]		[[Category: Pseudomonas aeruginosa pao1]]

OCA at 07:18, 4 March 2020

OCA — Wed, 04 Mar 2020 07:18:55 GMT

←Older revision		Revision as of 07:18, 4 March 2020
Line 3:		Line 3:
	<StructureSection load='6tup' size='340' side='right'caption='[[6tup]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='6tup' size='340' side='right'caption='[[6tup]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6tup]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa_(strain_atcc_15692_/_dsm_22644_/_cip_104116_/_jcm_14847_/_lmg_12228_/_1c_/_prs_101_/_pao1)~~ Pseudomonas aeruginosa ~~(strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 /~~ pao1)] and [http://en.wikipedia.org/wiki/Pseudomonas_virus_pf1 Pseudomonas virus pf1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TUP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6tup]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1] and [http://en.wikipedia.org/wiki/Pseudomonas_virus_pf1 Pseudomonas virus pf1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TUP FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tup OCA], [http://pdbe.org/6tup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tup RCSB], [http://www.ebi.ac.uk/pdbsum/6tup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tup ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tup OCA], [http://pdbe.org/6tup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tup RCSB], [http://www.ebi.ac.uk/pdbsum/6tup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tup ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The opportunistic pathogen Pseudomonas aeruginosa is a major cause of antibiotic-tolerant infections in humans. P. aeruginosa evades antibiotics in bacterial biofilms by up-regulating expression of a symbiotic filamentous inoviral prophage, Pf4. We investigated the mechanism of phage-mediated antibiotic tolerance using biochemical reconstitution combined with structural biology and high-resolution cellular imaging. We resolved electron cryomicroscopy atomic structures of Pf4 with and without its linear single-stranded DNA genome, and studied Pf4 assembly into liquid crystalline droplets using optical microscopy and electron cryotomography. By biochemically replicating conditions necessary for antibiotic protection, we found that phage liquid crystalline droplets form phase-separated occlusive compartments around rod-shaped bacteria leading to increased bacterial survival. Encapsulation by these compartments was observed even when inanimate colloidal rods were used to mimic rod-shaped bacteria, suggesting that shape and size complementarity profoundly influences the process. Filamentous inoviruses are pervasive across prokaryotes, and in particular, several Gram-negative bacterial pathogens including Neisseria meningitidis, Vibrio cholerae, and Salmonella enterica harbor these prophages. We propose that biophysical occlusion mediated by secreted filamentous molecules such as Pf4 may be a general strategy of bacterial survival in harsh environments.
		+
		+	Phage liquid crystalline droplets form occlusive sheaths that encapsulate and protect infectious rod-shaped bacteria.,Tarafder AK, von Kugelgen A, Mellul AJ, Schulze U, Aarts DGAL, Bharat TAM Proc Natl Acad Sci U S A. 2020 Feb 18. pii: 1917726117. doi:, 10.1073/pnas.1917726117. PMID:32071243<ref>PMID:32071243</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6tup" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Pseudomonas aeruginosa pao1]]
	[[Category: Pseudomonas virus pf1]]		[[Category: Pseudomonas virus pf1]]
	[[Category: Bharat, T A.M]]		[[Category: Bharat, T A.M]]

OCA at 09:25, 26 February 2020

OCA — Wed, 26 Feb 2020 09:25:48 GMT

←Older revision		Revision as of 09:25, 26 February 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6tup is ~~ON HOLD until Jan 08 2022~~	+	==Cryo-EM structure of Pf4 bacteriophage coat protein with single-stranded DNA==
-		+	<StructureSection load='6tup' size='340' side='right'caption='[[6tup]], [[Resolution\|resolution]] 3.20Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6tup]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_(strain_atcc_15692_/_dsm_22644_/_cip_104116_/_jcm_14847_/_lmg_12228_/_1c_/_prs_101_/_pao1) Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)] and [http://en.wikipedia.org/wiki/Pseudomonas_virus_pf1 Pseudomonas virus pf1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TUP FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tup OCA], [http://pdbe.org/6tup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tup RCSB], [http://www.ebi.ac.uk/pdbsum/6tup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tup ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Pseudomonas virus pf1]]
		+	[[Category: Bharat, T A.M]]
		+	[[Category: Kugelgen, A von]]
		+	[[Category: Tarafder, A K]]
		+	[[Category: Bacteriophage]]
		+	[[Category: Filamentous]]
		+	[[Category: Helical]]
		+	[[Category: Virus]]

OCA at 05:15, 19 February 2020

OCA — Wed, 19 Feb 2020 05:15:51 GMT

←Older revision		Revision as of 05:15, 19 February 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6tup is ON HOLD	+	The entry 6tup is ON HOLD until Jan 08 2022

	Authors:		Authors:

OCA: Protected "6tup" [edit=sysop:move=sysop]

OCA — Wed, 22 Jan 2020 13:55:40 GMT

Protected "6tup" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:55, 22 January 2020

OCA: New page: '''Unreleased structure''' The entry 6tup is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 22 Jan 2020 13:55:39 GMT

New page: '''Unreleased structure''' The entry 6tup is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6tup is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]