6tzv - Revision history

OCA at 14:56, 13 March 2024

OCA — Wed, 13 Mar 2024 14:56:14 GMT

←Older revision		Revision as of 14:56, 13 March 2024
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	==Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis==		==Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis==
-	<StructureSection load='6tzv' size='340' side='right'caption='[[6tzv]]' scene=''>	+	<StructureSection load='6tzv' size='340' side='right'caption='[[6tzv]], [[Resolution\|resolution]] 2.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TZV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6TZV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6tzv]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TZV FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6tzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tzv OCA], [~~http~~://pdbe.org/6tzv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6tzv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6tzv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6tzv ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.388Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PKP:4-[(6-chloro-1,3-benzothiazol-2-yl)oxy]-6-hydroxy-4,4-dimethyl-4,5-dihydro[1,1-biphenyl]-2(3H)-one'>PKP</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tzv OCA], [https://pdbe.org/6tzv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tzv RCSB], [https://www.ebi.ac.uk/pdbsum/6tzv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tzv ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ACCD6_MYCTU ACCD6_MYCTU] Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate (PubMed:17114269). When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA, with a preference for acetyl-CoA (PubMed:17114269).<ref>PMID:17114269</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Mycobacterium tuberculosis H37Rv]]
	[[Category: Reddy MCM]]		[[Category: Reddy MCM]]
	[[Category: Sacchettini J]]		[[Category: Sacchettini J]]
	[[Category: Zhou N]]		[[Category: Zhou N]]

OCA at 06:19, 19 August 2020

OCA — Wed, 19 Aug 2020 06:19:52 GMT

←Older revision		Revision as of 06:19, 19 August 2020
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-	'''Unreleased structure'''

-	~~The entry 6tzv is ON HOLD until Paper Publication~~	+	==Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis==
-		+	<StructureSection load='6tzv' size='340' side='right'caption='[[6tzv]]' scene=''>
-	~~Authors: Reddy, M.C.M., Zhou, N., Sacchettini, J., TB Structural Genomics Consortium (TBSGC)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TZV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TZV FirstGlance]. <br>
-	~~Description:~~ Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tzv OCA], [http://pdbe.org/6tzv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tzv RCSB], [http://www.ebi.ac.uk/pdbsum/6tzv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tzv ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Reddy~~, M.C.M]]	+	__TOC__
-	[[Category: ~~Zhou, N~~]]	+	</StructureSection>
-	[[Category: Sacchettini, J]]	+	[[Category: Large Structures]]
-	[[Category: ~~Tb Structural Genomics Consortium (Tbsgc)~~]]	+	[[Category: Reddy MCM]]
		+	[[Category: Sacchettini J]]
		+	[[Category: Zhou N]]

OCA at 03:51, 10 October 2019

OCA — Thu, 10 Oct 2019 03:51:13 GMT

←Older revision		Revision as of 03:51, 10 October 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6tzv is ON HOLD	+	The entry 6tzv is ON HOLD until Paper Publication

	Authors: Reddy, M.C.M., Zhou, N., Sacchettini, J., TB Structural Genomics Consortium (TBSGC)		Authors: Reddy, M.C.M., Zhou, N., Sacchettini, J., TB Structural Genomics Consortium (TBSGC)

OCA: Protected "6tzv" [edit=sysop:move=sysop]

OCA — Wed, 21 Aug 2019 04:26:17 GMT

Protected "6tzv" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:26, 21 August 2019

OCA: New page: '''Unreleased structure''' The entry 6tzv is ON HOLD Authors: Reddy, M.C.M., Zhou, N., Sacchettini, J., TB Structural Genomics Consortium (TBSGC) Description: Crystal Structure of the ...

OCA — Wed, 21 Aug 2019 04:26:15 GMT

New page: '''Unreleased structure''' The entry 6tzv is ON HOLD Authors: Reddy, M.C.M., Zhou, N., Sacchettini, J., TB Structural Genomics Consortium (TBSGC) Description: Crystal Structure of the ...

New page

'''Unreleased structure'''

The entry 6tzv is ON HOLD

Authors: Reddy, M.C.M., Zhou, N., Sacchettini, J., TB Structural Genomics Consortium (TBSGC)

Description: Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis
[[Category: Unreleased Structures]]
[[Category: Reddy, M.C.M]]
[[Category: Zhou, N]]
[[Category: Sacchettini, J]]
[[Category: Tb Structural Genomics Consortium (Tbsgc)]]