6up8 - Revision history

OCA at 14:57, 13 March 2024

OCA — Wed, 13 Mar 2024 14:57:53 GMT

←Older revision		Revision as of 14:57, 13 March 2024
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	==Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure==		==Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure==
-	<StructureSection load='6up8' size='340' side='right'caption='[[6up8]]' scene=''>	+	<StructureSection load='6up8' size='340' side='right'caption='[[6up8]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UP8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6UP8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6up8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UP8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6up8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6up8 OCA], [~~http~~://pdbe.org/6up8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6up8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6up8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6up8 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6up8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6up8 OCA], [https://pdbe.org/6up8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6up8 RCSB], [https://www.ebi.ac.uk/pdbsum/6up8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6up8 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[https://omim.org/entry/190450 190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN]
		+
		+	==See Also==
		+	*[[Triose phosphate isomerase 3D structures\|Triose phosphate isomerase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Romero JM]]		[[Category: Romero JM]]

OCA at 14:37, 8 July 2020

OCA — Wed, 08 Jul 2020 14:37:39 GMT

←Older revision		Revision as of 14:37, 8 July 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6up8 ~~is ON HOLD until Paper Publication~~	+	==Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure==
-		+	<StructureSection load='6up8' size='340' side='right'caption='[[6up8]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UP8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6UP8 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6up8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6up8 OCA], [http://pdbe.org/6up8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6up8 RCSB], [http://www.ebi.ac.uk/pdbsum/6up8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6up8 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Romero JM]]

OCA at 07:38, 30 October 2019

OCA — Wed, 30 Oct 2019 07:38:10 GMT

←Older revision		Revision as of 07:38, 30 October 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6up8 is ON HOLD	+	The entry 6up8 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6up8" [edit=sysop:move=sysop]

OCA — Wed, 23 Oct 2019 05:18:33 GMT

Protected "6up8" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:18, 23 October 2019

OCA: New page: '''Unreleased structure''' The entry 6up8 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 23 Oct 2019 05:18:31 GMT

New page: '''Unreleased structure''' The entry 6up8 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6up8 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]