6uww - Revision history

OCA at 07:59, 11 October 2023

OCA — Wed, 11 Oct 2023 07:59:58 GMT

←Older revision		Revision as of 07:59, 11 October 2023
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	==Crystal structure of dihydrofolate reductase from Mycobacterium ulcerans with P218 inhibitor==		==Crystal structure of dihydrofolate reductase from Mycobacterium ulcerans with P218 inhibitor==
-	<StructureSection load='6uww' size='340' side='right'caption='[[6uww]]' scene=''>	+	<StructureSection load='6uww' size='340' side='right'caption='[[6uww]], [[Resolution\|resolution]] 0.92Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UWW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6UWW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6uww]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_ulcerans_Agy99 Mycobacterium ulcerans Agy99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UWW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UWW FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6uww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uww OCA], [~~http~~://pdbe.org/6uww PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6uww RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6uww PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6uww ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 0.92Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MMV:3-(2-{3-[(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)OXY]PROPOXY}PHENYL)PROPANOIC+ACID'>MMV</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6uww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uww OCA], [https://pdbe.org/6uww PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6uww RCSB], [https://www.ebi.ac.uk/pdbsum/6uww PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6uww ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0PQG8_MYCUA A0PQG8_MYCUA] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194]
		+
		+	==See Also==
		+	*[[Dihydrofolate reductase 3D structures\|Dihydrofolate reductase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Mycobacterium ulcerans Agy99]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 07:58, 11 November 2020

OCA — Wed, 11 Nov 2020 07:58:40 GMT

←Older revision		Revision as of 07:58, 11 November 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6uww is ON HOLD until Paper Publication~~	+	==Crystal structure of dihydrofolate reductase from Mycobacterium ulcerans with P218 inhibitor==
-		+	<StructureSection load='6uww' size='340' side='right'caption='[[6uww]]' scene=''>
-	~~Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UWW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6UWW FirstGlance]. <br>
-	~~Description:~~ Crystal structure of dihydrofolate reductase from Mycobacterium ulcerans with P218 inhibitor	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6uww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uww OCA], [http://pdbe.org/6uww PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uww RCSB], [http://www.ebi.ac.uk/pdbsum/6uww PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uww ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Seattle~~ Structural ~~Genomics Center For Infectious Disease, Seattle Structural Genomics Center For Infectious Disease (Ssgcid)~~]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Structural genomic]]

OCA at 05:59, 18 December 2019

OCA — Wed, 18 Dec 2019 05:59:09 GMT

←Older revision		Revision as of 05:59, 18 December 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6uww is ON HOLD	+	The entry 6uww is ON HOLD until Paper Publication

	Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)		Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

OCA: Protected "6uww" [edit=sysop:move=sysop]

OCA — Wed, 13 Nov 2019 09:39:39 GMT

Protected "6uww" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:39, 13 November 2019

OCA: New page: '''Unreleased structure''' The entry 6uww is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCI...

OCA — Wed, 13 Nov 2019 09:39:37 GMT

New page: '''Unreleased structure''' The entry 6uww is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCI...

New page

'''Unreleased structure'''

The entry 6uww is ON HOLD

Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Description: Crystal structure of dihydrofolate reductase from Mycobacterium ulcerans with P218 inhibitor
[[Category: Unreleased Structures]]
[[Category: Seattle Structural Genomics Center For Infectious Disease, Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]