6ux0 - Revision history

OCA at 08:00, 11 October 2023

OCA — Wed, 11 Oct 2023 08:00:04 GMT

←Older revision		Revision as of 08:00, 11 October 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6ux0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_castellanii_str._Neff Acanthamoeba castellanii str. Neff]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UX0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[6ux0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_castellanii_str._Neff Acanthamoeba castellanii str. Neff]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UX0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=QKM:4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile'>QKM</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.93Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=QKM:4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile'>QKM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ux0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ux0 OCA], [https://pdbe.org/6ux0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ux0 RCSB], [https://www.ebi.ac.uk/pdbsum/6ux0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ux0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ux0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ux0 OCA], [https://pdbe.org/6ux0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ux0 RCSB], [https://www.ebi.ac.uk/pdbsum/6ux0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ux0 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/L8GJB3_ACACA L8GJB3_ACACA]]	+	[https://www.uniprot.org/uniprot/L8GJB3_ACACA L8GJB3_ACACA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:08, 8 September 2022

OCA — Thu, 08 Sep 2022 07:08:19 GMT

←Older revision		Revision as of 07:08, 8 September 2022
Line 3:		Line 3:
	<StructureSection load='6ux0' size='340' side='right'caption='[[6ux0]], [[Resolution\|resolution]] 2.93Å' scene=''>		<StructureSection load='6ux0' size='340' side='right'caption='[[6ux0]], [[Resolution\|resolution]] 2.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ux0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Acanthamoeba_castellanii_neff_strain~~ Acanthamoeba castellanii ~~neff strain~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UX0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ux0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_castellanii_str._Neff Acanthamoeba castellanii str. Neff]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UX0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=QKM:4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile'>QKM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=QKM:4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile'>QKM</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACA1_372720 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1257118 Acanthamoeba castellanii Neff strain])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ux0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ux0 OCA], [https://pdbe.org/6ux0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ux0 RCSB], [https://www.ebi.ac.uk/pdbsum/6ux0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ux0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ux0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ux0 OCA], [https://pdbe.org/6ux0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ux0 RCSB], [https://www.ebi.ac.uk/pdbsum/6ux0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ux0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/L8GJB3_ACACA L8GJB3_ACACA]]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Acanthamoeba castellanii ~~neff strain~~]]	+	[[Category: Acanthamoeba castellanii str. Neff]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Podust~~, L M~~]]	+	[[Category: Podust LM]]
-	[[Category: Sharma, V]]	+	[[Category: Sharma V]]
-	~~[[Category: 14- alpha-demethylase]]~~	+
-	~~[[Category: Acanthamoeba]]~~	+
-	~~[[Category: Cyp51]]~~	+
-	~~[[Category: Ergosterol biosynthesis]]~~	+
-	~~[[Category: Isavuconazole]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 16:17, 6 July 2022

OCA — Wed, 06 Jul 2022 16:17:51 GMT

←Older revision		Revision as of 16:17, 6 July 2022
Line 3:		Line 3:
	<StructureSection load='6ux0' size='340' side='right'caption='[[6ux0]], [[Resolution\|resolution]] 2.93Å' scene=''>		<StructureSection load='6ux0' size='340' side='right'caption='[[6ux0]], [[Resolution\|resolution]] 2.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ux0]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Acanthamoeba_castellanii_neff_strain Acanthamoeba castellanii neff strain]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UX0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6UX0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ux0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_castellanii_neff_strain Acanthamoeba castellanii neff strain]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UX0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=QKM:4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile'>QKM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=QKM:4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile'>QKM</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACA1_372720 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1257118 Acanthamoeba castellanii Neff strain])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACA1_372720 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1257118 Acanthamoeba castellanii Neff strain])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6ux0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ux0 OCA], [~~http~~://pdbe.org/6ux0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ux0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ux0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ux0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ux0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ux0 OCA], [https://pdbe.org/6ux0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ux0 RCSB], [https://www.ebi.ac.uk/pdbsum/6ux0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ux0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:11, 2 December 2020

OCA — Wed, 02 Dec 2020 08:11:10 GMT

←Older revision		Revision as of 08:11, 2 December 2020
Line 1:		Line 1:

	==Isavuconazole bound complex of Acanthamoeba castellanii CYP51==		==Isavuconazole bound complex of Acanthamoeba castellanii CYP51==
-	<StructureSection load='6ux0' size='340' side='right'caption='[[6ux0]]' scene=''>	+	<StructureSection load='6ux0' size='340' side='right'caption='[[6ux0]], [[Resolution\|resolution]] 2.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UX0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6UX0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ux0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Acanthamoeba_castellanii_neff_strain Acanthamoeba castellanii neff strain]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UX0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6UX0 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ux0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ux0 OCA], [http://pdbe.org/6ux0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ux0 RCSB], [http://www.ebi.ac.uk/pdbsum/6ux0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ux0 ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=QKM:4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile'>QKM</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACA1_372720 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1257118 Acanthamoeba castellanii Neff strain])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ux0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ux0 OCA], [http://pdbe.org/6ux0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ux0 RCSB], [http://www.ebi.ac.uk/pdbsum/6ux0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ux0 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cytochromes P450 (CYPs) metabolize a wide variety of endogenous and exogenous lipophilic compounds, including most drugs. Sterol 14alpha-demethylase (CYP51) is a target for anti-fungal drugs known as conazoles. Using x-ray crystallography, we have discovered a domain swap homo-dimerization mode in CYP51 from a human pathogen, Acanthamoeba castellanii, (AcCYP51). Recombinant AcCYP51 with a truncated trans-membrane helix was purified as a heterogeneous mixture corresponding to the dimer and monomer units. Spectral analyses of these two populations have shown that the carbon monoxide (CO)-bound ferrous form of the dimeric protein absorbed at 448 nm (catalytically competent form), whereas the monomeric form absorbed at 420 nm (catalytically incompetent form). AcCYP51 dimerized head-to-head via N-termini swapping, resulting in formation of a non-planar protein-protein interface exceeding 2000 A(2) with a total solvation energy gain of -35.4 kcal/mol. In the dimer, the protomers faced each other through the F and G alpha-helices, thus blocking the substrate access channel. In the presence of the drugs, clotrimazole and isavuconazole, the AcCYP51-drug complexes crystallized as monomers. While clotrimazole-bound AcCYP51 adopted a typical CYP monomer structure, isavuconazole-bound AcCYP51 failed to refold 74 N-terminal residues. This failure of CYP51 to fully refold upon inhibitor binding in vivo would cause an irreversible loss of a structurally aberrant enzyme through proteolytic degradation. This assumption explains the superior potency of isavuconazole against A. castellanii The dimerization mode observed in this work is compatible with membrane association and may be relevant to other members of the CYP family of biological, medical, and pharmacological importance. Significance Statement We investigated the mechanism of action of anti-fungal drugs in the human pathogen, A. castellanii We discovered that the enzyme target (AcCYP51) forms a dimer via an N-termini swap, whereas drug-bound AcCYP51 was monomeric. In the AcCYP51-isavuconazole complex, the protein target failed to refold 74 N-terminal residues suggesting a fundamentally different mechanism of AcCYP51 inactivation than only blocking the active site. Proteolytic degradation of a structurally aberrant enzyme would explain the superior potency of isavuconazole against A. castellanii.
		+
		+	Domain-swap dimerization of Acanthamoeba castellanii CYP51 and a unique mechanism of inactivation by isavuconazole.,Sharma V, Shing B, Hernandez-Alvarez L, Debnath A, Podust LM Mol Pharmacol. 2020 Oct 2. pii: molpharm.120.000092. doi:, 10.1124/molpharm.120.000092. PMID:33008918<ref>PMID:33008918</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6ux0" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Acanthamoeba castellanii neff strain]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Podust LM]]	+	[[Category: Podust, L M]]
-	[[Category: Sharma V]]	+	[[Category: Sharma, V]]
		+	[[Category: 14- alpha-demethylase]]
		+	[[Category: Acanthamoeba]]
		+	[[Category: Cyp51]]
		+	[[Category: Ergosterol biosynthesis]]
		+	[[Category: Isavuconazole]]
		+	[[Category: Oxidoreductase]]

OCA at 08:14, 21 October 2020

OCA — Wed, 21 Oct 2020 08:14:31 GMT

←Older revision		Revision as of 08:14, 21 October 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6ux0 ~~is ON HOLD until Nov 06 2021~~	+	==Isavuconazole bound complex of Acanthamoeba castellanii CYP51==
-		+	<StructureSection load='6ux0' size='340' side='right'caption='[[6ux0]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UX0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6UX0 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ux0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ux0 OCA], [http://pdbe.org/6ux0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ux0 RCSB], [http://www.ebi.ac.uk/pdbsum/6ux0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ux0 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Podust LM]]
		+	[[Category: Sharma V]]

OCA at 13:54, 20 November 2019

OCA — Wed, 20 Nov 2019 13:54:18 GMT

←Older revision		Revision as of 13:54, 20 November 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6ux0 is ON HOLD	+	The entry 6ux0 is ON HOLD until Nov 06 2021

	Authors:		Authors:

OCA: Protected "6ux0" [edit=sysop:move=sysop]

OCA — Wed, 13 Nov 2019 09:39:59 GMT

Protected "6ux0" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:39, 13 November 2019

OCA: New page: '''Unreleased structure''' The entry 6ux0 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 13 Nov 2019 09:39:58 GMT

New page: '''Unreleased structure''' The entry 6ux0 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6ux0 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]