6v6g - Revision history

OCA at 08:04, 11 October 2023

OCA — Wed, 11 Oct 2023 08:04:24 GMT

←Older revision		Revision as of 08:04, 11 October 2023
Line 3:		Line 3:
	<StructureSection load='6v6g' size='340' side='right'caption='[[6v6g]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='6v6g' size='340' side='right'caption='[[6v6g]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6v6g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V6G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6v6g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V6G FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~, ~~<scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[6v5e\|6v5e]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">blaCTX-M-14, beta-lactamase CTX-M-14, bla, bla CTX-M-14, bla-CTX-M-14a, blaCTX-M, blaCTX-M-14a, blaCTX-M-14b, blaCTX-M-14c, blaCTX-M-27b, blatoho-3, blaUOE-2, CTX-M-14, AM465_01285, AM465_06510, AM465_23360, APT94_14605, BEN53_26220, BET08_34355, BJJ90_27545, BK334_27290, BOH76_00730, BON63_16015, BON66_01305, BON69_22545, BON71_04040, BON75_10525, BON76_14325, BON81_01055, BON83_15455, BON86_08515, BON91_02075, BON92_04750, BON94_23850, BON95_01680, BON96_03940, BXT93_06855, C5N07_28500, C5P43_21980, CDL37_21060, CR538_26855, CRT46_23505, DW236_20870, EIA08_25160, EIA21_26975, ELT23_05930, ETN48_p0088, FNJ69_13810, FQR64_24895, FTV90_03295, pCT_085, pHK01_011, RCS103_P0010, RCS30_P0082, RCS56_P0085, RCS60_P0031, RCS63_P0006, RCS65_P0008, RCS66_P0053, SAMEA4362930_00013, SAMEA4370290_00046 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~562~~ "~~Bacillus coli~~" ~~Migula 1895])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v6g OCA], [https://pdbe.org/6v6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v6g RCSB], [https://www.ebi.ac.uk/pdbsum/6v6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v6g ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v6g OCA], [https://pdbe.org/6v6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v6g RCSB], [https://www.ebi.ac.uk/pdbsum/6v6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v6g ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9L5C7_ECOLX Q9L5C7_ECOLX]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895]]~~	+	[[Category: Escherichia coli]]
-	~~[[Category: Beta-lactamase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Brown~~, C A~~]]	+	[[Category: Brown CA]]
-	[[Category: Hu, L]]	+	[[Category: Hu L]]
-	[[Category: Palzkill~~, T G~~]]	+	[[Category: Palzkill TG]]
-	[[Category: Prasad~~, B V.V~~]]	+	[[Category: Prasad BVV]]
-	[[Category: Sankaran, B]]	+	[[Category: Sankaran B]]
-	~~[[Category: Conformational change]]~~	+
-	~~[[Category: Drug resistance]]~~	+
-	~~[[Category: Enzyme catalysis]]~~	+
-	~~[[Category: Enzyme kinetic]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Protein evolution]]~~	+
-	~~[[Category: Protein stability]]~~	+
-	~~[[Category: Protein structure]]~~	+
-	~~[[Category: Protein-drug interaction~~]]	+

OCA at 03:44, 2 July 2021

OCA — Fri, 02 Jul 2021 03:44:32 GMT

←Older revision		Revision as of 03:44, 2 July 2021
Line 33:		Line 33:
	[[Category: Palzkill, T G]]		[[Category: Palzkill, T G]]
	[[Category: Prasad, B V.V]]		[[Category: Prasad, B V.V]]
		+	[[Category: Sankaran, B]]
	[[Category: Conformational change]]		[[Category: Conformational change]]
	[[Category: Drug resistance]]		[[Category: Drug resistance]]

OCA at 15:26, 8 June 2021

OCA — Tue, 08 Jun 2021 15:26:35 GMT

←Older revision		Revision as of 15:26, 8 June 2021
Line 3:		Line 3:
	<StructureSection load='6v6g' size='340' side='right'caption='[[6v6g]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='6v6g' size='340' side='right'caption='[[6v6g]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6v6g]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V6G OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6V6G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6v6g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V6G FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6v5e\|6v5e]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6v5e\|6v5e]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaCTX-M-14, beta-lactamase CTX-M-14, bla, bla CTX-M-14, bla-CTX-M-14a, blaCTX-M, blaCTX-M-14a, blaCTX-M-14b, blaCTX-M-14c, blaCTX-M-27b, blatoho-3, blaUOE-2, CTX-M-14, AM465_01285, AM465_06510, AM465_23360, APT94_14605, BEN53_26220, BET08_34355, BJJ90_27545, BK334_27290, BOH76_00730, BON63_16015, BON66_01305, BON69_22545, BON71_04040, BON75_10525, BON76_14325, BON81_01055, BON83_15455, BON86_08515, BON91_02075, BON92_04750, BON94_23850, BON95_01680, BON96_03940, BXT93_06855, C5N07_28500, C5P43_21980, CDL37_21060, CR538_26855, CRT46_23505, DW236_20870, EIA08_25160, EIA21_26975, ELT23_05930, ETN48_p0088, FNJ69_13810, FQR64_24895, FTV90_03295, pCT_085, pHK01_011, RCS103_P0010, RCS30_P0082, RCS56_P0085, RCS60_P0031, RCS63_P0006, RCS65_P0008, RCS66_P0053, SAMEA4362930_00013, SAMEA4370290_00046 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaCTX-M-14, beta-lactamase CTX-M-14, bla, bla CTX-M-14, bla-CTX-M-14a, blaCTX-M, blaCTX-M-14a, blaCTX-M-14b, blaCTX-M-14c, blaCTX-M-27b, blatoho-3, blaUOE-2, CTX-M-14, AM465_01285, AM465_06510, AM465_23360, APT94_14605, BEN53_26220, BET08_34355, BJJ90_27545, BK334_27290, BOH76_00730, BON63_16015, BON66_01305, BON69_22545, BON71_04040, BON75_10525, BON76_14325, BON81_01055, BON83_15455, BON86_08515, BON91_02075, BON92_04750, BON94_23850, BON95_01680, BON96_03940, BXT93_06855, C5N07_28500, C5P43_21980, CDL37_21060, CR538_26855, CRT46_23505, DW236_20870, EIA08_25160, EIA21_26975, ELT23_05930, ETN48_p0088, FNJ69_13810, FQR64_24895, FTV90_03295, pCT_085, pHK01_011, RCS103_P0010, RCS30_P0082, RCS56_P0085, RCS60_P0031, RCS63_P0006, RCS65_P0008, RCS66_P0053, SAMEA4362930_00013, SAMEA4370290_00046 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6v6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v6g OCA], [~~http~~://pdbe.org/6v6g PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6v6g RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6v6g PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6v6g ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v6g OCA], [https://pdbe.org/6v6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v6g RCSB], [https://www.ebi.ac.uk/pdbsum/6v6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v6g ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:13, 20 July 2020

OCA — Mon, 20 Jul 2020 09:13:23 GMT

←Older revision		Revision as of 09:13, 20 July 2020
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 6v6g" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6v6g" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-lactamase 3D structures\|Beta-lactamase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:14, 29 April 2020

OCA — Wed, 29 Apr 2020 07:14:13 GMT

←Older revision		Revision as of 07:14, 29 April 2020
Line 1:		Line 1:

	==Crystal structure of CTX-M-14 E166A/P167S/D240G beta-lactamase==		==Crystal structure of CTX-M-14 E166A/P167S/D240G beta-lactamase==
-	<StructureSection load='6v6g' size='340' side='right'caption='[[6v6g]]' scene=''>	+	<StructureSection load='6v6g' size='340' side='right'caption='[[6v6g]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V6G OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6V6G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6v6g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V6G OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6V6G FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6v6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v6g OCA], [http://pdbe.org/6v6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6v6g RCSB], [http://www.ebi.ac.uk/pdbsum/6v6g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6v6g ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6v5e\|6v5e]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaCTX-M-14, beta-lactamase CTX-M-14, bla, bla CTX-M-14, bla-CTX-M-14a, blaCTX-M, blaCTX-M-14a, blaCTX-M-14b, blaCTX-M-14c, blaCTX-M-27b, blatoho-3, blaUOE-2, CTX-M-14, AM465_01285, AM465_06510, AM465_23360, APT94_14605, BEN53_26220, BET08_34355, BJJ90_27545, BK334_27290, BOH76_00730, BON63_16015, BON66_01305, BON69_22545, BON71_04040, BON75_10525, BON76_14325, BON81_01055, BON83_15455, BON86_08515, BON91_02075, BON92_04750, BON94_23850, BON95_01680, BON96_03940, BXT93_06855, C5N07_28500, C5P43_21980, CDL37_21060, CR538_26855, CRT46_23505, DW236_20870, EIA08_25160, EIA21_26975, ELT23_05930, ETN48_p0088, FNJ69_13810, FQR64_24895, FTV90_03295, pCT_085, pHK01_011, RCS103_P0010, RCS30_P0082, RCS56_P0085, RCS60_P0031, RCS63_P0006, RCS65_P0008, RCS66_P0053, SAMEA4362930_00013, SAMEA4370290_00046 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6v6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v6g OCA], [http://pdbe.org/6v6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6v6g RCSB], [http://www.ebi.ac.uk/pdbsum/6v6g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6v6g ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	CTX-M beta-lactamases are widespread in Gram-negative bacterial pathogens and provide resistance to the cephalosporin cefotaxime, but not to the related antibiotic, ceftazidime. Nevertheless, variants have emerged that confer resistance to ceftazidime. Two natural mutations, causing P167S and D240G substitutions in the CTX-M enzyme, result in 10-fold increased hydrolysis of ceftazidime. Although the combination of these mutations would be predicted to increase ceftazidime hydrolysis further, the P167S/D240G combination has not been observed in a naturally occurring CTX-M variant. Here, using recombinantly expressed enzymes, minimum inhibitory concentration measurements, steady-state enzyme kinetics, and X-ray crystallography, we show that the P167S/D240G double mutant enzyme exhibits decreased ceftazidime hydrolysis, lower thermostability, and decreased protein expression levels compared with each of the single mutants, indicating negative epistasis. X-ray structures of mutant enzymes with covalently trapped ceftazidime suggested that a change of an active site Omega-loop to an open conformation accommodates ceftazidime leading to enhanced catalysis. Ten microseconds of molecular dynamics simulations further correlated Omega-loop opening with catalytic activity. We observed that the wild type and P167S/D240G variant with acylated ceftazidime both favor a closed conformation not conducive for catalysis. In contrast, the single substitutions dramatically increased the probability of open conformations. We conclude that the antagonism is due to restricting the conformation of the Omega-loop. These results reveal the importance of conformational heterogeneity of active site loops in controlling catalytic activity and directing evolutionary trajectories.
		+
		+	Antagonism between substitutions in beta-lactamase explains a path not taken in the evolution of bacterial drug resistance.,Brown CA, Hu L, Sun Z, Patel MP, Singh S, Porter JR, Sankaran B, Prasad BVV, Bowman GR, Palzkill T J Biol Chem. 2020 Apr 16. pii: RA119.012489. doi: 10.1074/jbc.RA119.012489. PMID:32299911<ref>PMID:32299911</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6v6g" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus coli migula 1895]]
		+	[[Category: Beta-lactamase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Brown CA]]	+	[[Category: Brown, C A]]
-	[[Category: Hu L]]	+	[[Category: Hu, L]]
-	[[Category: Palzkill TG]]	+	[[Category: Palzkill, T G]]
-	[[Category: Prasad ~~BVV~~]]	+	[[Category: Prasad, B V.V]]
		+	[[Category: Conformational change]]
		+	[[Category: Drug resistance]]
		+	[[Category: Enzyme catalysis]]
		+	[[Category: Enzyme kinetic]]
		+	[[Category: Hydrolase]]
		+	[[Category: Protein evolution]]
		+	[[Category: Protein stability]]
		+	[[Category: Protein structure]]
		+	[[Category: Protein-drug interaction]]

OCA at 05:47, 22 April 2020

OCA — Wed, 22 Apr 2020 05:47:21 GMT

←Older revision		Revision as of 05:47, 22 April 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6v6g is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of CTX-M-14 E166A/P167S/D240G beta-lactamase==
-		+	<StructureSection load='6v6g' size='340' side='right'caption='[[6v6g]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V6G OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6V6G FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6v6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v6g OCA], [http://pdbe.org/6v6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6v6g RCSB], [http://www.ebi.ac.uk/pdbsum/6v6g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6v6g ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Brown CA]]
		+	[[Category: Hu L]]
		+	[[Category: Palzkill TG]]
		+	[[Category: Prasad BVV]]

OCA at 06:01, 18 December 2019

OCA — Wed, 18 Dec 2019 06:01:48 GMT

←Older revision		Revision as of 06:01, 18 December 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6v6g is ON HOLD	+	The entry 6v6g is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6v6g" [edit=sysop:move=sysop]

OCA — Wed, 11 Dec 2019 13:49:22 GMT

Protected "6v6g" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:49, 11 December 2019

OCA: New page: '''Unreleased structure''' The entry 6v6g is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 11 Dec 2019 13:49:20 GMT

New page: '''Unreleased structure''' The entry 6v6g is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6v6g is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]