6v8c - Revision history

OCA at 08:05, 11 October 2023

OCA — Wed, 11 Oct 2023 08:05:45 GMT

←Older revision		Revision as of 08:05, 11 October 2023
Line 1:		Line 1:

	==Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of GAMA-Aminobutyric Acid (GABA) as Selective Ornithine Aminotransferase Inactivators==		==Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of GAMA-Aminobutyric Acid (GABA) as Selective Ornithine Aminotransferase Inactivators==
-	<StructureSection load='6v8c' size='340' side='right'caption='[[6v8c]]' scene=''>	+	<StructureSection load='6v8c' size='340' side='right'caption='[[6v8c]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V8C OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6V8C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6v8c]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V8C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V8C FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6v8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v8c OCA], [~~http~~://pdbe.org/6v8c PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6v8c RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6v8c PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6v8c ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=QRM:3-aminocyclohexa-1,3-diene-1-carboxylic+acid'>QRM</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v8c OCA], [https://pdbe.org/6v8c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v8c RCSB], [https://www.ebi.ac.uk/pdbsum/6v8c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v8c ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/OAT_HUMAN OAT_HUMAN] Defects in OAT are the cause of hyperornithinemia with gyrate atrophy of choroid and retina (HOGA) [MIM:[https://omim.org/entry/258870 258870]. HOGA is a slowly progressive blinding autosomal recessive disorder.<ref>PMID:3375240</ref> <ref>PMID:2793865</ref> <ref>PMID:1612597</ref> <ref>PMID:1737786</ref> <ref>PMID:7887415</ref> <ref>PMID:7668253</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/OAT_HUMAN OAT_HUMAN]
		+
		+	==See Also==
		+	*[[Aminotransferase 3D structures\|Aminotransferase 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Butrin A]]		[[Category: Butrin A]]

OCA at 12:31, 16 December 2020

OCA — Wed, 16 Dec 2020 12:31:33 GMT

←Older revision		Revision as of 12:31, 16 December 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6v8c is ~~ON HOLD until Paper Publication~~	+	==Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of GAMA-Aminobutyric Acid (GABA) as Selective Ornithine Aminotransferase Inactivators==
-		+	<StructureSection load='6v8c' size='340' side='right'caption='[[6v8c]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V8C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6V8C FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6v8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v8c OCA], [http://pdbe.org/6v8c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6v8c RCSB], [http://www.ebi.ac.uk/pdbsum/6v8c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6v8c ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Butrin A]]
		+	[[Category: Catlin DS]]
		+	[[Category: Doubleday PT]]
		+	[[Category: Kelleher NL]]
		+	[[Category: Liu D]]
		+	[[Category: Shen S]]
		+	[[Category: Silverman RB]]
		+	[[Category: Weerawarna P]]
		+	[[Category: Zhu W]]

OCA at 05:09, 25 November 2020

OCA — Wed, 25 Nov 2020 05:09:03 GMT

←Older revision		Revision as of 05:09, 25 November 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6v8c is ON HOLD	+	The entry 6v8c is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 18:47, 28 October 2020

OCA — Wed, 28 Oct 2020 18:47:51 GMT

←Older revision		Revision as of 18:47, 28 October 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6v8c is ON HOLD ~~until sometime in the future~~	+	The entry 6v8c is ON HOLD

	Authors:		Authors:

OCA at 05:16, 19 February 2020

OCA — Wed, 19 Feb 2020 05:16:27 GMT

←Older revision		Revision as of 05:16, 19 February 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6v8c is ON HOLD	+	The entry 6v8c is ON HOLD until sometime in the future

	Authors:		Authors:

OCA: Protected "6v8c" [edit=sysop:move=sysop]

OCA — Wed, 18 Dec 2019 06:06:06 GMT

Protected "6v8c" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:06, 18 December 2019

OCA: New page: '''Unreleased structure''' The entry 6v8c is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 18 Dec 2019 06:06:05 GMT

New page: '''Unreleased structure''' The entry 6v8c is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6v8c is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]