6va5 - Revision history

OCA at 08:07, 11 October 2023

OCA — Wed, 11 Oct 2023 08:07:09 GMT

←Older revision		Revision as of 08:07, 11 October 2023
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	==Tudor Domain of Tumor suppressor p53BP1 with MFP-4184==		==Tudor Domain of Tumor suppressor p53BP1 with MFP-4184==
-	<StructureSection load='6va5' size='340' side='right'caption='[[6va5]]' scene=''>	+	<StructureSection load='6va5' size='340' side='right'caption='[[6va5]], [[Resolution\|resolution]] 1.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VA5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6VA5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6va5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VA5 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6va5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6va5 OCA], [~~http~~://pdbe.org/6va5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6va5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6va5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6va5 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.28Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=QSS:2-(4-methylpiperazin-1-yl)aniline'>QSS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6va5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6va5 OCA], [https://pdbe.org/6va5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6va5 RCSB], [https://www.ebi.ac.uk/pdbsum/6va5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6va5 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN] Note=A chromosomal aberration involving TP53BP1 is found in a form of myeloproliferative disorder chronic with eosinophilia. Translocation t(5;15)(q33;q22) with PDGFRB creating a TP53BP1-PDGFRB fusion protein.
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN] Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.<ref>PMID:12364621</ref> <ref>PMID:17190600</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Arrowsmith CH]]		[[Category: Arrowsmith CH]]

OCA at 06:47, 29 April 2020

OCA — Wed, 29 Apr 2020 06:47:06 GMT

←Older revision		Revision as of 06:47, 29 April 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6va5 ~~is ON HOLD~~	+	==Tudor Domain of Tumor suppressor p53BP1 with MFP-4184==
-		+	<StructureSection load='6va5' size='340' side='right'caption='[[6va5]]' scene=''>
-	~~Authors~~: ~~The, J~~.~~, Dong, A~~.~~, Headey, S~~.~~, Gunzburg, M~~.~~, Doak, B~~.~~, James, L~~.I.~~, Bountra, C~~., ~~Arrowsmith, C~~.H., ~~Edwards~~, A.M., ~~Brown~~, P.J.~~, Structural Genomics Consortium (SGC)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VA5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6VA5 FirstGlance]. <br>
-	~~Description: Tudor Domain of Tumor suppressor p53BP1 with MFP-4184~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6va5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6va5 OCA], [http://pdbe.org/6va5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6va5 RCSB], [http://www.ebi.ac.uk/pdbsum/6va5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6va5 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Gunzburg, M~~]]	+	__TOC__
-	[[Category: ~~James, L.I]]~~	+	</StructureSection>
-	~~[[Category: Arrowsmith,~~ C.H]]	+	[[Category: Large Structures]]
-	[[Category: ~~Dong, A~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: ~~Brown, P.J~~]]	+	[[Category: Bountra C]]
-	[[Category: ~~Edwards,~~ A.M]]	+	[[Category: Brown PJ]]
-	[[Category: ~~Headey, S~~]]	+	[[Category: Doak B]]
-	[[Category: ~~The, J~~]]	+	[[Category: Dong A]]
-	[[Category: ~~Structural Genomics Consortium (Sgc)~~]]	+	[[Category: Edwards AM]]
-	[[Category: ~~Doak, B~~]]	+	[[Category: Gunzburg M]]
-	[[Category: ~~Bountra, C~~]]	+	[[Category: Headey S]]
		+	[[Category: James LI]]
		+	[[Category: Zeng H]]

OCA: Protected "6va5" [edit=sysop:move=sysop]

OCA — Wed, 25 Dec 2019 07:34:20 GMT

Protected "6va5" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:34, 25 December 2019

OCA: New page: '''Unreleased structure''' The entry 6va5 is ON HOLD Authors: The, J., Dong, A., Headey, S., Gunzburg, M., Doak, B., James, L.I., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P....

OCA — Wed, 25 Dec 2019 07:34:18 GMT

New page: '''Unreleased structure''' The entry 6va5 is ON HOLD Authors: The, J., Dong, A., Headey, S., Gunzburg, M., Doak, B., James, L.I., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P....

New page

'''Unreleased structure'''

The entry 6va5 is ON HOLD

Authors: The, J., Dong, A., Headey, S., Gunzburg, M., Doak, B., James, L.I., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Structural Genomics Consortium (SGC)

Description: Tudor Domain of Tumor suppressor p53BP1 with MFP-4184
[[Category: Unreleased Structures]]
[[Category: Gunzburg, M]]
[[Category: James, L.I]]
[[Category: Arrowsmith, C.H]]
[[Category: Dong, A]]
[[Category: Brown, P.J]]
[[Category: Edwards, A.M]]
[[Category: Headey, S]]
[[Category: The, J]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Doak, B]]
[[Category: Bountra, C]]