6wgi - Revision history

OCA at 14:44, 6 March 2024

OCA — Wed, 06 Mar 2024 14:44:12 GMT

←Older revision		Revision as of 14:44, 6 March 2024
Line 1:		Line 1:

-	====	+	==Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution==
-	<StructureSection load='6wgi' size='340' side='right'caption='[[6wgi]]' scene=''>	+	<StructureSection load='6wgi' size='340' side='right'caption='[[6wgi]], [[Resolution\|resolution]] 10.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6wgi]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WGI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6wgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wgi OCA], [~~http~~://pdbe.org/6wgi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6wgi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6wgi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6wgi ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 10Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wgi OCA], [https://pdbe.org/6wgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wgi RCSB], [https://www.ebi.ac.uk/pdbsum/6wgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wgi ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CDC6_YEAST CDC6_YEAST] Plays a crucial role in forming the pre-replicative complexes. Interacts with the origin recognition complex (ORC) and MCM2-7 helicase complex leading to the linking of those complexes and loading of the replicative helicase MCM2-7 onto the pre-replicative complexes. Required for the initiation of DNA replication and then actively participates in the suppression of nuclear division.<ref>PMID:10075735</ref> <ref>PMID:1600944</ref> <ref>PMID:23603117</ref> <ref>PMID:7641697</ref> <ref>PMID:8538771</ref> <ref>PMID:8978693</ref> <ref>PMID:9099949</ref> <ref>PMID:9312054</ref> <ref>PMID:9892652</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Z~~-disk~~]]	+	[[Category: Saccharomyces cerevisiae]]
		+	[[Category: Bai L]]
		+	[[Category: Dodd T]]
		+	[[Category: Ivanov I]]
		+	[[Category: Li H]]
		+	[[Category: Magdalou I]]
		+	[[Category: Riera A]]
		+	[[Category: Schneider S]]
		+	[[Category: Speck C]]
		+	[[Category: Stillman B]]
		+	[[Category: Yan C]]
		+	[[Category: Yuan Z]]

OCA at 11:44, 22 July 2020

OCA — Wed, 22 Jul 2020 11:44:19 GMT

←Older revision		Revision as of 11:44, 22 July 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6wgi ~~is ON HOLD until sometime in the future~~	+	====
-		+	<StructureSection load='6wgi' size='340' side='right'caption='[[6wgi]]' scene=''>
-	~~Authors~~: ~~Yuan, Z~~.~~, Schneider, S~~.~~, Dodd, T~~.~~, Riera, A~~.~~, Bai, L~~.~~, Yan, C~~.~~, Magdalou, I~~.~~, Ivanov, I., Stillman, B., Li, H., Speck, C.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~: ~~Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wgi OCA], [http://pdbe.org/6wgi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wgi RCSB], [http://www.ebi.ac.uk/pdbsum/6wgi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wgi ProSAT]</span></td></tr>
-	[~~[Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[~~[Category~~: ~~Bai, L~~]]	+	__TOC__
-	~~[[Category: Riera~~, ~~A]]~~	+	</StructureSection>
-	[~~[Category~~: ~~Li, H~~]]	+	[[Category: Large Structures]]
-	~~[[Category: Ivanov~~, ~~I]]~~	+	[[Category: Z-disk]]
-	[~~[Category~~: ~~Yuan, Z~~]]	+
-	~~[[Category: Dodd~~, ~~T]]~~	+
-	[~~[Category~~: ~~Yan, C~~]]	+
-	~~[[Category: Stillman~~, ~~B]]~~	+
-	[~~[Category~~: ~~Speck, C]~~]	+
-	[[Category: ~~Schneider, S~~]]	+
-	[[Category: ~~Magdalou, I~~]]	+

OCA: Protected "6wgi" [edit=sysop:move=sysop]

OCA — Wed, 15 Apr 2020 05:26:01 GMT

Protected "6wgi" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:26, 15 April 2020

OCA: New page: '''Unreleased structure''' The entry 6wgi is ON HOLD until sometime in the future Authors: Yuan, Z., Schneider, S., Dodd, T., Riera, A., Bai, L., Yan, C., Magdalou, I., Ivanov, I., Stil...

OCA — Wed, 15 Apr 2020 05:26:00 GMT

New page: '''Unreleased structure''' The entry 6wgi is ON HOLD until sometime in the future Authors: Yuan, Z., Schneider, S., Dodd, T., Riera, A., Bai, L., Yan, C., Magdalou, I., Ivanov, I., Stil...

New page

'''Unreleased structure'''

The entry 6wgi is ON HOLD until sometime in the future

Authors: Yuan, Z., Schneider, S., Dodd, T., Riera, A., Bai, L., Yan, C., Magdalou, I., Ivanov, I., Stillman, B., Li, H., Speck, C.

Description: Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6
[[Category: Unreleased Structures]]
[[Category: Bai, L]]
[[Category: Riera, A]]
[[Category: Li, H]]
[[Category: Ivanov, I]]
[[Category: Yuan, Z]]
[[Category: Dodd, T]]
[[Category: Yan, C]]
[[Category: Stillman, B]]
[[Category: Speck, C]]
[[Category: Schneider, S]]
[[Category: Magdalou, I]]