OCA at 14:37, 18 October 2023

OCA — Wed, 18 Oct 2023 14:37:50 GMT

←Older revision		Revision as of 14:37, 18 October 2023
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	==Chicken SPCS1==		==Chicken SPCS1==
-	<StructureSection load='6wve' size='340' side='right'caption='[[6wve]]' scene=''>	+	<StructureSection load='6wve' size='340' side='right'caption='[[6wve]], [[Resolution\|resolution]] 2.43Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WVE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6WVE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6wve]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WVE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6wve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wve OCA], [~~http~~://pdbe.org/6wve PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6wve RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6wve PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6wve ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.429Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CRO:{2-[(1R,2R)-1-AMINO-2-HYDROXYPROPYL]-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>CRO</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wve OCA], [https://pdbe.org/6wve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wve RCSB], [https://www.ebi.ac.uk/pdbsum/6wve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wve ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/GFP_AEQVI GFP_AEQVI] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin.[https://www.uniprot.org/uniprot/E1BX11_CHICK E1BX11_CHICK]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Small membrane proteins are difficult targets for structural characterization. Here, we stabilize their folding by restraining their amino and carboxyl termini with associable protein entities, exemplified by the two halves of a superfolder GFP. The termini-restrained proteins are functional and show improved stability during overexpression and purification. The reassembled GFP provides a versatile scaffold for membrane protein crystallization, enables diffraction to atomic resolution, and facilitates crystal identification, phase determination, and density modification. This strategy gives rise to 14 new structures of five vertebrate proteins from distinct functional families, bringing a substantial expansion to the structural database of small membrane proteins. Moreover, a high-resolution structure of bacterial DsbB reveals that this thiol oxidoreductase is activated through a catalytic triad, similar to cysteine proteases. Overall, termini restraining proves exceptionally effective for stabilization and structure determination of small membrane proteins.
		+
		+	Termini restraining of small membrane proteins enables structure determination at near-atomic resolution.,Liu S, Li S, Yang Y, Li W Sci Adv. 2020 Dec 18;6(51). pii: 6/51/eabe3717. doi: 10.1126/sciadv.abe3717., Print 2020 Dec. PMID:33355146<ref>PMID:33355146</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6wve" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Green Fluorescent Protein 3D structures\|Green Fluorescent Protein 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Aequorea victoria]]
		+	[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Li W]]		[[Category: Li W]]
	[[Category: Liu S]]		[[Category: Liu S]]

OCA at 05:49, 20 January 2021

OCA — Wed, 20 Jan 2021 05:49:49 GMT

←Older revision		Revision as of 05:49, 20 January 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 6wve ~~is ON HOLD~~	+	==Chicken SPCS1==
-		+	<StructureSection load='6wve' size='340' side='right'caption='[[6wve]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WVE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6WVE FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wve OCA], [http://pdbe.org/6wve PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wve RCSB], [http://www.ebi.ac.uk/pdbsum/6wve PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wve ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Li W]]
		+	[[Category: Liu S]]

OCA: Protected "6wve" [edit=sysop:move=sysop]

OCA — Wed, 13 May 2020 04:11:11 GMT

Protected "6wve" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:11, 13 May 2020

OCA: New page: '''Unreleased structure''' The entry 6wve is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 13 May 2020 04:11:09 GMT

New page: '''Unreleased structure''' The entry 6wve is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6wve is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

6wve - Revision history

OCA at 14:37, 18 October 2023

OCA at 05:49, 20 January 2021

OCA: Protected "6wve" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 6wve is ON HOLD Authors: Description: Category: Unreleased Structures