6x7r - Revision history

OCA at 09:16, 25 October 2023

OCA — Wed, 25 Oct 2023 09:16:43 GMT

←Older revision		Revision as of 09:16, 25 October 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6x7r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._DH10B Escherichia coli str. K-12 substr. DH10B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6X7R FirstGlance]. <br>		<table><tr><td colspan='2'>[[6x7r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._DH10B Escherichia coli str. K-12 substr. DH10B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6X7R FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UT7:oxa(dethia)-CoA'>UT7</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.35Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UT7:oxa(dethia)-CoA'>UT7</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6x7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6x7r OCA], [https://pdbe.org/6x7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6x7r RCSB], [https://www.ebi.ac.uk/pdbsum/6x7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6x7r ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6x7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6x7r OCA], [https://pdbe.org/6x7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6x7r RCSB], [https://www.ebi.ac.uk/pdbsum/6x7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6x7r ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:41, 8 March 2023

OCA — Wed, 08 Mar 2023 07:41:16 GMT

←Older revision		Revision as of 07:41, 8 March 2023
Line 3:		Line 3:
	<StructureSection load='6x7r' size='340' side='right'caption='[[6x7r]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='6x7r' size='340' side='right'caption='[[6x7r]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6x7r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecodh Ecodh~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6X7R FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6x7r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._DH10B Escherichia coli str. K-12 substr. DH10B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6X7R FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UT7:oxa(dethia)-CoA'>UT7</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UT7:oxa(dethia)-CoA'>UT7</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabH, b1091, JW1077 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=316385 ECODH])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_III Beta-ketoacyl-[acyl-carrier-protein] synthase III], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.180 2.3.1.180] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6x7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6x7r OCA], [https://pdbe.org/6x7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6x7r RCSB], [https://www.ebi.ac.uk/pdbsum/6x7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6x7r ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6x7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6x7r OCA], [https://pdbe.org/6x7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6x7r RCSB], [https://www.ebi.ac.uk/pdbsum/6x7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6x7r ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/FABH_ECOLI FABH_ECOLI]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for acetyl-CoA. Its substrate specificity determines the biosynthesis of straight-chain of fatty acids instead of branched-chain.[HAMAP-Rule:MF_01815]	+	[https://www.uniprot.org/uniprot/FABH_ECOLI FABH_ECOLI] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for acetyl-CoA. Its substrate specificity determines the biosynthesis of straight-chain of fatty acids instead of branched-chain.[HAMAP-Rule:MF_01815]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecodh~~]]	+	[[Category: Escherichia coli str. K-12 substr. DH10B]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Benjamin~~, A B~~]]	+	[[Category: Benjamin AB]]
-	[[Category: Ling, J]]	+	[[Category: Ling J]]
-	[[Category: Lohman~~, J R~~]]	+	[[Category: Lohman JR]]
-	[[Category: Nice~~, J N~~]]	+	[[Category: Nice JN]]
-	[[Category: Stunkard~~, L M]]~~	+	[[Category: Stunkard LM]]
-	~~[[Category: Ketoacyl synthase]]~~	+
-	~~[[Category: Substrate analog]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 05:14, 15 June 2022

OCA — Wed, 15 Jun 2022 05:14:16 GMT

←Older revision		Revision as of 05:14, 15 June 2022
Line 1:		Line 1:

	==E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) in complex with oxa(dethia)-coenzyme A==		==E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) in complex with oxa(dethia)-coenzyme A==
-	<StructureSection load='6x7r' size='340' side='right'caption='[[6x7r]]' scene=''>	+	<StructureSection load='6x7r' size='340' side='right'caption='[[6x7r]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6X7R FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6x7r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecodh Ecodh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6X7R FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6x7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6x7r OCA], [https://pdbe.org/6x7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6x7r RCSB], [https://www.ebi.ac.uk/pdbsum/6x7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6x7r ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UT7:oxa(dethia)-CoA'>UT7</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabH, b1091, JW1077 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=316385 ECODH])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_III Beta-ketoacyl-[acyl-carrier-protein] synthase III], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.180 2.3.1.180] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6x7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6x7r OCA], [https://pdbe.org/6x7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6x7r RCSB], [https://www.ebi.ac.uk/pdbsum/6x7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6x7r ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/FABH_ECOLI FABH_ECOLI]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for acetyl-CoA. Its substrate specificity determines the biosynthesis of straight-chain of fatty acids instead of branched-chain.[HAMAP-Rule:MF_01815]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Ecodh]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Benjamin AB]]	+	[[Category: Benjamin, A B]]
-	[[Category: Ling J]]	+	[[Category: Ling, J]]
-	[[Category: Lohman JR]]	+	[[Category: Lohman, J R]]
-	[[Category: Nice JN]]	+	[[Category: Nice, J N]]
-	[[Category: Stunkard LM]]	+	[[Category: Stunkard, L M]]
		+	[[Category: Ketoacyl synthase]]
		+	[[Category: Substrate analog]]
		+	[[Category: Transferase]]

OCA at 14:32, 2 June 2021

OCA — Wed, 02 Jun 2021 14:32:41 GMT

←Older revision		Revision as of 14:32, 2 June 2021
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6x7r is ON HOLD until Paper Publication~~	+	==E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) in complex with oxa(dethia)-coenzyme A==
-		+	<StructureSection load='6x7r' size='340' side='right'caption='[[6x7r]]' scene=''>
-	~~Authors: Benjamin, A.B., Stunkard, L.M., Ling, J., Nice, J.N., Lohman, J.R.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6X7R FirstGlance]. <br>
-	~~Description:~~ E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) in complex with oxa(dethia)-coenzyme A	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6x7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6x7r OCA], [https://pdbe.org/6x7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6x7r RCSB], [https://www.ebi.ac.uk/pdbsum/6x7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6x7r ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Nice, J.N~~]]	+	__TOC__
-	[[Category: Ling, J]]	+	</StructureSection>
-	[[Category: Lohman~~, J.R~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Benjamin, A.B~~]]	+	[[Category: Benjamin AB]]
-	[[Category: Stunkard~~, L.M~~]]	+	[[Category: Ling J]]
		+	[[Category: Lohman JR]]
		+	[[Category: Nice JN]]
		+	[[Category: Stunkard LM]]

OCA: Protected "6x7r" [edit=sysop:move=sysop]

OCA — Wed, 10 Jun 2020 04:57:48 GMT

Protected "6x7r" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:57, 10 June 2020

OCA: New page: '''Unreleased structure''' The entry 6x7r is ON HOLD until Paper Publication Authors: Benjamin, A.B., Stunkard, L.M., Ling, J., Nice, J.N., Lohman, J.R. Description: E. coli beta-ketoa...

OCA — Wed, 10 Jun 2020 04:57:46 GMT

New page: '''Unreleased structure''' The entry 6x7r is ON HOLD until Paper Publication Authors: Benjamin, A.B., Stunkard, L.M., Ling, J., Nice, J.N., Lohman, J.R. Description: E. coli beta-ketoa...

New page

'''Unreleased structure'''

The entry 6x7r is ON HOLD until Paper Publication

Authors: Benjamin, A.B., Stunkard, L.M., Ling, J., Nice, J.N., Lohman, J.R.

Description: E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) in complex with oxa(dethia)-coenzyme A
[[Category: Unreleased Structures]]
[[Category: Nice, J.N]]
[[Category: Ling, J]]
[[Category: Lohman, J.R]]
[[Category: Benjamin, A.B]]
[[Category: Stunkard, L.M]]