6xwq - Revision history

OCA at 10:20, 22 May 2024

OCA — Wed, 22 May 2024 10:20:16 GMT

←Older revision		Revision as of 10:20, 22 May 2024
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	<SX load='6xwq' size='340' side='right' viewer='molstar' caption='[[6xwq]], [[Resolution\|resolution]] 3.41Å' scene=''>		<SX load='6xwq' size='340' side='right' viewer='molstar' caption='[[6xwq]], [[Resolution\|resolution]] 3.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6xwq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XWQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6XWQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6xwq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_kodakarensis_KOD1 Thermococcus kodakarensis KOD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XWQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XWQ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.41Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[6xwo\|6xwo]], [[6xwp\|6xwp]], [[6xwr\|6xwr]], [[6xwn\|6xwn]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6xwq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xwq OCA], [~~http~~://pdbe.org/6xwq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6xwq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6xwq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6xwq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xwq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xwq OCA], [https://pdbe.org/6xwq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xwq RCSB], [https://www.ebi.ac.uk/pdbsum/6xwq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xwq ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q5JID0_THEKO Q5JID0_THEKO]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6xwq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6xwq" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Symporter 3D structures\|Symporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</SX>		</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Arkhipova, V~~]]	+	[[Category: Thermococcus kodakarensis KOD1]]
-	[[Category: ~~Guskov, A~~]]	+	[[Category: Arkhipova V]]
-	[[Category: ~~Slotboom, D J~~]]	+	[[Category: Guskov A]]
-	[[Category: ~~Amino acid transporter]]~~	+	[[Category: Slotboom DJ]]
-	~~[[Category: Aspartate transport]]~~	+
-	~~[[Category: Glutamate transporter homologue]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 07:12, 11 April 2020

OCA — Sat, 11 Apr 2020 07:12:31 GMT

←Older revision		Revision as of 07:12, 11 April 2020
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	<SX load='6xwq' size='340' side='right' viewer='molstar' caption='[[6xwq]], [[Resolution\|resolution]] 3.41Å' scene=''>		<SX load='6xwq' size='340' side='right' viewer='molstar' caption='[[6xwq]], [[Resolution\|resolution]] 3.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6xwq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XWQ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6XWQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6xwq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XWQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6XWQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6xwo\|6xwo]], [[6xwp\|6xwp]], [[6xwr\|6xwr]], [[6xwn\|6xwn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6xwo\|6xwo]], [[6xwp\|6xwp]], [[6xwr\|6xwr]], [[6xwn\|6xwn]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6xwq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xwq OCA], [http://pdbe.org/6xwq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6xwq RCSB], [http://www.ebi.ac.uk/pdbsum/6xwq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6xwq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6xwq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xwq OCA], [http://pdbe.org/6xwq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6xwq RCSB], [http://www.ebi.ac.uk/pdbsum/6xwq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6xwq ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:27, 7 March 2020

OCA — Sat, 07 Mar 2020 01:27:13 GMT

←Older revision		Revision as of 01:27, 7 March 2020
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	==Structure of glutamate transporter homologue GltTk in the saturated conditions==		==Structure of glutamate transporter homologue GltTk in the saturated conditions==
-	<~~StructureSection~~ load='6xwq' size='340' side='right'caption='[[6xwq]], [[Resolution\|resolution]] 3.41Å' scene=''>	+	<SX load='6xwq' size='340' side='right' viewer='molstar' caption='[[6xwq]], [[Resolution\|resolution]] 3.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6xwq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XWQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6XWQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[6xwq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XWQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6XWQ FirstGlance]. <br>
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	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Arkhipova, V]]		[[Category: Arkhipova, V]]

OCA at 06:59, 4 March 2020

OCA — Wed, 04 Mar 2020 06:59:21 GMT

←Older revision		Revision as of 06:59, 4 March 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6xwq is ~~ON HOLD until Paper~~ Publication	+	==Structure of glutamate transporter homologue GltTk in the saturated conditions==
		+	<StructureSection load='6xwq' size='340' side='right'caption='[[6xwq]], [[Resolution\|resolution]] 3.41Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6xwq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XWQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6XWQ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6xwo\|6xwo]], [[6xwp\|6xwp]], [[6xwr\|6xwr]], [[6xwn\|6xwn]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6xwq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xwq OCA], [http://pdbe.org/6xwq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6xwq RCSB], [http://www.ebi.ac.uk/pdbsum/6xwq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6xwq ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glutamate transporters are cation-coupled secondary active membrane transporters that clear the neurotransmitter L-glutamate from the synaptic cleft. These transporters are homotrimers, with each protomer functioning independently by an elevator-type mechanism, in which a mobile transport domain alternates between inward- and outward-oriented states. Using single-particle cryo-EM we have determined five structures of the glutamate transporter homologue GltTk, a Na(+)- L-aspartate symporter, embedded in lipid nanodiscs. Dependent on the substrate concentrations used, the protomers of the trimer adopt a variety of asymmetrical conformations, consistent with the independent movement. Six of the 15 resolved protomers are in a hitherto elusive state of the transport cycle in which the inward-facing transporters are loaded with Na(+) ions. These structures explain how substrate-leakage is prevented - a strict requirement for coupled transport. The belt protein of the lipid nanodiscs bends around the inward oriented protomers, suggesting that membrane deformations occur during transport.

-	~~Authors~~:	+	Structural ensemble of a glutamate transporter homologue in lipid nanodisc environment.,Arkhipova V, Guskov A, Slotboom DJ Nat Commun. 2020 Feb 21;11(1):998. doi: 10.1038/s41467-020-14834-8. PMID:32081874<ref>PMID:32081874</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6xwq" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Arkhipova, V]]
		+	[[Category: Guskov, A]]
		+	[[Category: Slotboom, D J]]
		+	[[Category: Amino acid transporter]]
		+	[[Category: Aspartate transport]]
		+	[[Category: Glutamate transporter homologue]]
		+	[[Category: Membrane protein]]
		+	[[Category: Transport protein]]

OCA at 06:25, 5 February 2020

OCA — Wed, 05 Feb 2020 06:25:59 GMT

←Older revision		Revision as of 06:25, 5 February 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6xwq is ON HOLD	+	The entry 6xwq is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6xwq" [edit=sysop:move=sysop]

OCA — Wed, 29 Jan 2020 13:53:21 GMT

Protected "6xwq" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:53, 29 January 2020

OCA: New page: '''Unreleased structure''' The entry 6xwq is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 29 Jan 2020 13:53:19 GMT

New page: '''Unreleased structure''' The entry 6xwq is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6xwq is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]