6y42 - Revision history

OCA at 13:19, 24 January 2024

OCA — Wed, 24 Jan 2024 13:19:07 GMT

←Older revision		Revision as of 13:19, 24 January 2024
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	<StructureSection load='6y42' size='340' side='right'caption='[[6y42]], [[Resolution\|resolution]] 4.30Å' scene=''>		<StructureSection load='6y42' size='340' side='right'caption='[[6y42]], [[Resolution\|resolution]] 4.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6y42]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Strvp Strvp~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y42 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6Y42 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6y42]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_venezuelae_ATCC_10712 Streptomyces venezuelae ATCC 10712]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y42 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y42 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 4.3Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~SVEN_6563 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=953739 STRVP]~~)</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6y42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y42 OCA], [~~http~~://pdbe.org/6y42 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6y42 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6y42 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6y42 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y42 OCA], [https://pdbe.org/6y42 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y42 RCSB], [https://www.ebi.ac.uk/pdbsum/6y42 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y42 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/F2RGC9_STRVP F2RGC9_STRVP]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Strvp~~]]	+	[[Category: Streptomyces venezuelae ATCC 10712]]
-	[[Category: Fontecilla-Camps~~, J C~~]]	+	[[Category: Fontecilla-Camps JC]]
-	[[Category: Volbeda, A]]	+	[[Category: Volbeda A]]
-	~~[[Category: Dna complex]]~~	+
-	~~[[Category: Iron sulfur cluster]]~~	+
-	~~[[Category: Redox sensor]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 10:52, 27 March 2020

OCA — Fri, 27 Mar 2020 10:52:02 GMT

←Older revision		Revision as of 10:52, 27 March 2020
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	<StructureSection load='6y42' size='340' side='right'caption='[[6y42]], [[Resolution\|resolution]] 4.30Å' scene=''>		<StructureSection load='6y42' size='340' side='right'caption='[[6y42]], [[Resolution\|resolution]] 4.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6y42]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y42 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Y42 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6y42]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Strvp Strvp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y42 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Y42 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SVEN_6563 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=953739 STRVP])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6y42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y42 OCA], [http://pdbe.org/6y42 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y42 RCSB], [http://www.ebi.ac.uk/pdbsum/6y42 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y42 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6y42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y42 OCA], [http://pdbe.org/6y42 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y42 RCSB], [http://www.ebi.ac.uk/pdbsum/6y42 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y42 ProSAT]</span></td></tr>
	</table>		</table>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Strvp]]
	[[Category: Fontecilla-Camps, J C]]		[[Category: Fontecilla-Camps, J C]]
	[[Category: Volbeda, A]]		[[Category: Volbeda, A]]

OCA at 07:00, 4 March 2020

OCA — Wed, 04 Mar 2020 07:00:09 GMT

←Older revision		Revision as of 07:00, 4 March 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6y42 is ~~ON HOLD~~	+	==Crystal Structure of RsrR complexed to a 39 basepair DNA fragment of the rsrR promoter==
		+	<StructureSection load='6y42' size='340' side='right'caption='[[6y42]], [[Resolution\|resolution]] 4.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6y42]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y42 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Y42 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6y42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y42 OCA], [http://pdbe.org/6y42 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y42 RCSB], [http://www.ebi.ac.uk/pdbsum/6y42 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y42 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The [Fe2S2]-RsrR gene transcription regulator senses the redox status in bacteria by modulating DNA binding, while its cluster cycles between +1 and +2 states-only the latter binds DNA. We have previously shown that RsrR can undergo remarkable conformational changes involving a 100 degrees rotation of tryptophan 9 between exposed (Out) and buried (In) states. Here, we have used the chemical modification of Trp9, site-directed mutagenesis, and crystallographic and computational chemical studies to show that (i) the Out and In states correspond to oxidized and reduced RsrR, respectively, (ii) His33 is protonated in the In state due to a change in its pKa caused by cluster reduction, and (iii) Trp9 rotation is conditioned by the response of its dipole moment to environmental electrostatic changes. Our findings illustrate a novel function of protonation resulting from electron transfer.

-	~~Authors~~:	+	Electron and Proton Transfers Modulate DNA Binding by the Transcription Regulator RsrR.,Crack JC, Amara P, Volbeda A, Mouesca JM, Rohac R, Pellicer Martinez MT, Huang CY, Gigarel O, Rinaldi C, Le Brun NE, Fontecilla-Camps JC J Am Chem Soc. 2020 Mar 3. doi: 10.1021/jacs.9b12250. PMID:32078310<ref>PMID:32078310</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6y42" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Fontecilla-Camps, J C]]
		+	[[Category: Volbeda, A]]
		+	[[Category: Dna complex]]
		+	[[Category: Iron sulfur cluster]]
		+	[[Category: Redox sensor]]
		+	[[Category: Transcription]]

OCA: Protected "6y42" [edit=sysop:move=sysop]

OCA — Wed, 26 Feb 2020 08:21:04 GMT

Protected "6y42" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:21, 26 February 2020

OCA: New page: '''Unreleased structure''' The entry 6y42 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 26 Feb 2020 08:21:03 GMT

New page: '''Unreleased structure''' The entry 6y42 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6y42 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]