6yqz - Revision history

OCA at 07:40, 1 May 2024

OCA — Wed, 01 May 2024 07:40:09 GMT

←Older revision		Revision as of 07:40, 1 May 2024
Line 1:		Line 1:

	==N-terminal domain of BRD4 with biphenyl-methyamino-dimethylpyridazinone==		==N-terminal domain of BRD4 with biphenyl-methyamino-dimethylpyridazinone==
-	<StructureSection load='6yqz' size='340' side='right'caption='[[6yqz]]' scene=''>	+	<StructureSection load='6yqz' size='340' side='right'caption='[[6yqz]], [[Resolution\|resolution]] 1.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YQZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6yqz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YQZ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yqz OCA], [https://pdbe.org/6yqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yqz RCSB], [https://www.ebi.ac.uk/pdbsum/6yqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yqz ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.39Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=P8W:2,4-dimethyl-5-[(2-phenylphenyl)methylamino]pyridazin-3-one'>P8W</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yqz OCA], [https://pdbe.org/6yqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yqz RCSB], [https://www.ebi.ac.uk/pdbsum/6yqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yqz ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
		+
		+	==See Also==
		+	*[[Bromodomain-containing protein 3D structures\|Bromodomain-containing protein 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Chung C]]		[[Category: Chung C]]

OCA at 06:38, 24 March 2021

OCA — Wed, 24 Mar 2021 06:38:32 GMT

←Older revision		Revision as of 06:38, 24 March 2021
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6yqz is ON HOLD until Paper Publication~~	+	==N-terminal domain of BRD4 with biphenyl-methyamino-dimethylpyridazinone==
-		+	<StructureSection load='6yqz' size='340' side='right'caption='[[6yqz]]' scene=''>
-	~~Authors: Chung, C.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YQZ FirstGlance]. <br>
-	~~Description:~~ N-terminal domain of BRD4 with biphenyl-methyamino-dimethylpyridazinone	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yqz OCA], [https://pdbe.org/6yqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yqz RCSB], [https://www.ebi.ac.uk/pdbsum/6yqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yqz ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Chung, C]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Chung C]]

OCA: Protected "6yqz" [edit=sysop:move=sysop]

OCA — Wed, 29 Apr 2020 05:25:54 GMT

Protected "6yqz" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:25, 29 April 2020

OCA: New page: '''Unreleased structure''' The entry 6yqz is ON HOLD until Paper Publication Authors: Chung, C. Description: N-terminal domain of BRD4 with biphenyl-methyamino-dimethylpyridazinone [[C...

OCA — Wed, 29 Apr 2020 05:25:53 GMT

New page: '''Unreleased structure''' The entry 6yqz is ON HOLD until Paper Publication Authors: Chung, C. Description: N-terminal domain of BRD4 with biphenyl-methyamino-dimethylpyridazinone [[C...

New page

'''Unreleased structure'''

The entry 6yqz is ON HOLD until Paper Publication

Authors: Chung, C.

Description: N-terminal domain of BRD4 with biphenyl-methyamino-dimethylpyridazinone
[[Category: Unreleased Structures]]
[[Category: Chung, C]]