6ywu - Revision history

OCA at 13:37, 24 January 2024

OCA — Wed, 24 Jan 2024 13:37:19 GMT

←Older revision		Revision as of 13:37, 24 January 2024
Line 3:		Line 3:
	<StructureSection load='6ywu' size='340' side='right'caption='[[6ywu]], [[Resolution\|resolution]] 1.10Å' scene=''>		<StructureSection load='6ywu' size='340' side='right'caption='[[6ywu]], [[Resolution\|resolution]] 1.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ywu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YWU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ywu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YWU FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.1Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ywu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ywu OCA], [https://pdbe.org/6ywu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ywu RCSB], [https://www.ebi.ac.uk/pdbsum/6ywu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ywu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ywu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ywu OCA], [https://pdbe.org/6ywu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ywu RCSB], [https://www.ebi.ac.uk/pdbsum/6ywu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ywu ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[https://www.uniprot.org/uniprot/UMPS_HUMAN UMPS_HUMAN]] Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:[https://omim.org/entry/258900 258900]]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies.<ref>PMID:9042911</ref>	+	[https://www.uniprot.org/uniprot/UMPS_HUMAN UMPS_HUMAN] Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:[https://omim.org/entry/258900 258900]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies.<ref>PMID:9042911</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/UMPS_HUMAN UMPS_HUMAN]
		+
		+	==See Also==
		+	*[[Uridine 5'-monophosphate synthase 3D structures\|Uridine 5'-monophosphate synthase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Krull, M]]	+	[[Category: Krull M]]
-	[[Category: Rindfleisch, S]]	+	[[Category: Rindfleisch S]]
-	[[Category: Tittmann, K]]	+	[[Category: Tittmann K]]
-	~~[[Category: Bmp]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Ompd]]~~	+
-	~~[[Category: Orotidine 5'-monophosphate decarboxylase]]~~	+
-	~~[[Category: Ump~~]]	+

OCA at 12:59, 4 May 2022

OCA — Wed, 04 May 2022 12:59:57 GMT

←Older revision		Revision as of 12:59, 4 May 2022
Line 1:		Line 1:

	==Human OMPD-domain of UMPS (K314AcK) in complex with UMP at 1.1 Angstroms resolution==		==Human OMPD-domain of UMPS (K314AcK) in complex with UMP at 1.1 Angstroms resolution==
-	<StructureSection load='6ywu' size='340' side='right'caption='[[6ywu]]' scene=''>	+	<StructureSection load='6ywu' size='340' side='right'caption='[[6ywu]], [[Resolution\|resolution]] 1.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YWU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ywu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YWU FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ywu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ywu OCA], [https://pdbe.org/6ywu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ywu RCSB], [https://www.ebi.ac.uk/pdbsum/6ywu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ywu ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ywu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ywu OCA], [https://pdbe.org/6ywu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ywu RCSB], [https://www.ebi.ac.uk/pdbsum/6ywu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ywu ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[[https://www.uniprot.org/uniprot/UMPS_HUMAN UMPS_HUMAN]] Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:[https://omim.org/entry/258900 258900]]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies.<ref>PMID:9042911</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Krull M]]	+	[[Category: Krull, M]]
-	[[Category: Rindfleisch S]]	+	[[Category: Rindfleisch, S]]
-	[[Category: Tittmann K]]	+	[[Category: Tittmann, K]]
		+	[[Category: Bmp]]
		+	[[Category: Lyase]]
		+	[[Category: Ompd]]
		+	[[Category: Orotidine 5'-monophosphate decarboxylase]]
		+	[[Category: Ump]]

OCA at 07:40, 23 February 2022

OCA — Wed, 23 Feb 2022 07:40:03 GMT

←Older revision		Revision as of 07:40, 23 February 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6ywu is ON HOLD until Paper Publication~~	+	==Human OMPD-domain of UMPS (K314AcK) in complex with UMP at 1.1 Angstroms resolution==
-		+	<StructureSection load='6ywu' size='340' side='right'caption='[[6ywu]]' scene=''>
-	~~Authors: Tittmann, K., Rindfleisch, S., Krull, M.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YWU FirstGlance]. <br>
-	~~Description:~~ Human OMPD-domain of UMPS (K314AcK) in complex with UMP at 1.1 Angstroms resolution	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ywu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ywu OCA], [https://pdbe.org/6ywu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ywu RCSB], [https://www.ebi.ac.uk/pdbsum/6ywu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ywu ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Tittmann~~, K]]	+	__TOC__
-	[[Category: Krull, M]]	+	</StructureSection>
-	[[Category: Rindfleisch, S]]	+	[[Category: Large Structures]]
		+	[[Category: Krull M]]
		+	[[Category: Rindfleisch S]]
		+	[[Category: Tittmann K]]

OCA at 07:37, 22 July 2020

OCA — Wed, 22 Jul 2020 07:37:50 GMT

←Older revision		Revision as of 07:37, 22 July 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6ywu is ON HOLD	+	The entry 6ywu is ON HOLD until Paper Publication

	Authors: Tittmann, K., Rindfleisch, S., Krull, M.		Authors: Tittmann, K., Rindfleisch, S., Krull, M.

OCA: Protected "6ywu" [edit=sysop:move=sysop]

OCA — Wed, 06 May 2020 04:48:19 GMT

Protected "6ywu" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:48, 6 May 2020

OCA: New page: '''Unreleased structure''' The entry 6ywu is ON HOLD Authors: Tittmann, K., Rindfleisch, S., Krull, M. Description: Human OMPD-domain of UMPS (K314AcK) in complex with UMP at 1.1 Angst...

OCA — Wed, 06 May 2020 04:48:18 GMT

New page: '''Unreleased structure''' The entry 6ywu is ON HOLD Authors: Tittmann, K., Rindfleisch, S., Krull, M. Description: Human OMPD-domain of UMPS (K314AcK) in complex with UMP at 1.1 Angst...

New page

'''Unreleased structure'''

The entry 6ywu is ON HOLD

Authors: Tittmann, K., Rindfleisch, S., Krull, M.

Description: Human OMPD-domain of UMPS (K314AcK) in complex with UMP at 1.1 Angstroms resolution
[[Category: Unreleased Structures]]
[[Category: Tittmann, K]]
[[Category: Krull, M]]
[[Category: Rindfleisch, S]]