6z1p - Revision history

OCA at 10:22, 22 May 2024

OCA — Wed, 22 May 2024 10:22:49 GMT

←Older revision		Revision as of 10:22, 22 May 2024
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	<StructureSection load='6z1p' size='340' side='right'caption='[[6z1p]], [[Resolution\|resolution]] 3.70Å' scene=''>		<StructureSection load='6z1p' size='340' side='right'caption='[[6z1p]], [[Resolution\|resolution]] 3.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6z1p]] is a 99 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Tetts Tetts~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z1P OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6Z1P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6z1p]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetrahymena_thermophila_SB210 Tetrahymena thermophila SB210]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Z1P FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN~~</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.7Å</td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK~~</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6z1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z1p OCA], [~~http~~://pdbe.org/6z1p PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6z1p RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6z1p PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6z1p ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6z1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z1p OCA], [https://pdbe.org/6z1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6z1p RCSB], [https://www.ebi.ac.uk/pdbsum/6z1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6z1p ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/Q24C34_TETTS Q24C34_TETTS]] One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.[ARBA:ARBA00004072] [[http://www.uniprot.org/uniprot/Q22HG3_TETTS Q22HG3_TETTS]] One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.[ARBA:ARBA00002570]	+	[https://www.uniprot.org/uniprot/Q23UD3_TETTS Q23UD3_TETTS]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6z1p" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6z1p" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ribosome 3D structures\|Ribosome 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Tetts~~]]	+	[[Category: Tetrahymena thermophila SB210]]
-	[[Category: Amunts, A]]	+	[[Category: Amunts A]]
-	[[Category: Tobiasson, V]]	+	[[Category: Tobiasson V]]
-	~~[[Category: Ciliate]]~~	+
-	~~[[Category: Mitochondria]]~~	+
-	~~[[Category: Mitochondrial ribosome]]~~	+
-	~~[[Category: Ribosome]]~~	+
-	~~[[Category: Tetrahymena~~]]	+

OCA at 08:33, 11 November 2020

OCA — Wed, 11 Nov 2020 08:33:12 GMT

←Older revision		Revision as of 08:33, 11 November 2020
Line 1:		Line 1:

	==Structure of the mitochondrial ribosome from Tetrahymena thermophila==		==Structure of the mitochondrial ribosome from Tetrahymena thermophila==
-	<StructureSection load='6z1p' size='340' side='right'caption='[[6z1p]]' scene=''>	+	<StructureSection load='6z1p' size='340' side='right'caption='[[6z1p]], [[Resolution\|resolution]] 3.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z1P OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6Z1P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6z1p]] is a 99 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetts Tetts]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z1P OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6Z1P FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6z1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z1p OCA], [http://pdbe.org/6z1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6z1p RCSB], [http://www.ebi.ac.uk/pdbsum/6z1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6z1p ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6z1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z1p OCA], [http://pdbe.org/6z1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6z1p RCSB], [http://www.ebi.ac.uk/pdbsum/6z1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6z1p ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/Q24C34_TETTS Q24C34_TETTS]] One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.[ARBA:ARBA00004072] [[http://www.uniprot.org/uniprot/Q22HG3_TETTS Q22HG3_TETTS]] One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.[ARBA:ARBA00002570]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	To understand the steps involved in the evolution of translation, we used Tetrahymena thermophila, a ciliate with high coding capacity of the mitochondrial genome, as the model organism and characterized its mitochondrial ribosome (mitoribosome) using cryo-EM. The structure of the mitoribosome reveals an assembly of 94-ribosomal proteins and four-rRNAs with an additional protein mass of ~700 kDa on the small subunit, while the large subunit lacks 5S rRNA. The structure also shows that the small subunit head is constrained, tRNA binding sites are formed by mitochondria-specific protein elements, conserved protein bS1 is excluded, and bacterial RNA polymerase binding site is blocked. We provide evidence for anintrinsic protein targeting system through visualization of mitochondria-specific mL105 by the exit tunnel that would facilitate the recruitment of a nascent polypeptide. Functional protein uS3m is encoded by three complementary genes from the nucleus and mitochondrion, establishing a link between genetic drift and mitochondrial translation. Finally, we reannotated nine open reading frames in the mitochondrial genome that code for mitoribosomal proteins.
		+
		+	Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation.,Tobiasson V, Amunts A Elife. 2020 Jun 18;9. pii: 59264. doi: 10.7554/eLife.59264. PMID:32553108<ref>PMID:32553108</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6z1p" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Amunts A]]	+	[[Category: Tetts]]
-	[[Category: Tobiasson V]]	+	[[Category: Amunts, A]]
		+	[[Category: Tobiasson, V]]
		+	[[Category: Ciliate]]
		+	[[Category: Mitochondria]]
		+	[[Category: Mitochondrial ribosome]]
		+	[[Category: Ribosome]]
		+	[[Category: Tetrahymena]]

OCA at 06:33, 25 June 2020

OCA — Thu, 25 Jun 2020 06:33:32 GMT

←Older revision		Revision as of 06:33, 25 June 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6z1p ~~is ON HOLD~~	+	==Structure of the mitochondrial ribosome from Tetrahymena thermophila==
-		+	<StructureSection load='6z1p' size='340' side='right'caption='[[6z1p]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z1P OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6Z1P FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6z1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z1p OCA], [http://pdbe.org/6z1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6z1p RCSB], [http://www.ebi.ac.uk/pdbsum/6z1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6z1p ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Amunts A]]
		+	[[Category: Tobiasson V]]

OCA: Protected "6z1p" [edit=sysop:move=sysop]

OCA — Wed, 20 May 2020 04:32:57 GMT

Protected "6z1p" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:32, 20 May 2020

OCA: New page: '''Unreleased structure''' The entry 6z1p is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 20 May 2020 04:32:56 GMT

New page: '''Unreleased structure''' The entry 6z1p is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6z1p is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]