OCA at 07:40, 1 May 2024

OCA — Wed, 01 May 2024 07:40:36 GMT

←Older revision		Revision as of 07:40, 1 May 2024
Line 1:		Line 1:

-	====	+	==Crystal structure of Uba4-Urm1 from Chaetomium thermophilum==
-	<StructureSection load='6z6s' size='340' side='right'caption='[[6z6s]]' scene=''>	+	<StructureSection load='6z6s' size='340' side='right'caption='[[6z6s]], [[Resolution\|resolution]] 3.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6z6s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Z6S FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6z6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z6s OCA], [~~http~~://pdbe.org/6z6s PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6z6s RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6z6s PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6z6s ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.153Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6z6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z6s OCA], [https://pdbe.org/6z6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6z6s RCSB], [https://www.ebi.ac.uk/pdbsum/6z6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6z6s ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G0SC54_CHATD G0SC54_CHATD] Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions.[HAMAP-Rule:MF_03049]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chaetomium thermophilum var. thermophilum DSM 1495]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Ethiraju Ravichandran K]]
		+	[[Category: Glatt S]]
		+	[[Category: Grudnik P]]
		+	[[Category: Pabis M]]

OCA at 10:57, 22 July 2020

OCA — Wed, 22 Jul 2020 10:57:52 GMT

←Older revision		Revision as of 10:57, 22 July 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6z6s ~~is ON HOLD~~	+	====
-		+	<StructureSection load='6z6s' size='340' side='right'caption='[[6z6s]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6z6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z6s OCA], [http://pdbe.org/6z6s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6z6s RCSB], [http://www.ebi.ac.uk/pdbsum/6z6s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6z6s ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA: Protected "6z6s" [edit=sysop:move=sysop]

OCA — Wed, 10 Jun 2020 05:06:35 GMT

Protected "6z6s" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:06, 10 June 2020

OCA: New page: '''Unreleased structure''' The entry 6z6s is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 10 Jun 2020 05:06:34 GMT

New page: '''Unreleased structure''' The entry 6z6s is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6z6s is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

6z6s - Revision history

OCA at 07:40, 1 May 2024

OCA at 10:57, 22 July 2020

OCA: Protected "6z6s" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 6z6s is ON HOLD Authors: Description: Category: Unreleased Structures