6zhh - Revision history

OCA at 13:49, 24 January 2024

OCA — Wed, 24 Jan 2024 13:49:45 GMT

←Older revision		Revision as of 13:49, 24 January 2024
Line 3:		Line 3:
	<StructureSection load='6zhh' size='340' side='right'caption='[[6zhh]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='6zhh' size='340' side='right'caption='[[6zhh]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6zhh]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium~~ monocytogenes ~~hominis" nyfeldt 1932~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZHH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6zhh]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZHH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=CE1:O-DODECANYL+OCTAETHYLENE+GLYCOL'>CE1</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">A3R04_02860 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1639 "Bacterium monocytogenes hominis" Nyfeldt 1932])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=CE1:O-DODECANYL+OCTAETHYLENE+GLYCOL'>CE1</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zhh OCA], [https://pdbe.org/6zhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zhh RCSB], [https://www.ebi.ac.uk/pdbsum/6zhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zhh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zhh OCA], [https://pdbe.org/6zhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zhh RCSB], [https://www.ebi.ac.uk/pdbsum/6zhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zhh ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/LMCA1_LISMO LMCA1_LISMO] Catalyzes the hydrolysis of ATP coupled with the transport of calcium. The transport is electrogenic with a probable ATP:Ca(2+):H(+) stoichiometry of 1:1:1. May have an important role in survival of the bacterium when stressed by a combination of a high calcium concentration and alkaline pH.<ref>PMID:21047776</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 6zhh" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6zhh" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[ATPase 3D structures\|ATPase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Andersen, J Lauwring]]~~	+	[[Category: Listeria monocytogenes]]
-	~~[[Category: Dyla, M~~]]	+	[[Category: Basse Hansen S]]
-	[[Category: Hansen, S ~~Basse~~]]	+	[[Category: Dyla M]]
-	[[Category: ~~Kjaergaard,~~ M]]	+	[[Category: Kjaergaard M]]
-	[[Category: ~~Neumann, C~~]]	+	[[Category: Lauwring Andersen J]]
-	[[Category: ~~Nissen, P~~]]	+	[[Category: Neumann C]]
-	[[Category: ~~Quistgaard, E M.H]]~~	+	[[Category: Nissen P]]
-	~~[[Category: Listeria monocytogene~~]]	+	[[Category: Quistgaard EMH]]
-	[[Category: P~~-type atpase calcium pump~~]]	+
-	[[Category: ~~Transport protein~~]]	+

OCA at 10:43, 28 July 2021

OCA — Wed, 28 Jul 2021 10:43:52 GMT

←Older revision		Revision as of 10:43, 28 July 2021
Line 1:		Line 1:

	==Ca2+-ATPase from Listeria Monocytogenes with G4 insertion.==		==Ca2+-ATPase from Listeria Monocytogenes with G4 insertion.==
-	<StructureSection load='6zhh' size='340' side='right'caption='[[6zhh]]' scene=''>	+	<StructureSection load='6zhh' size='340' side='right'caption='[[6zhh]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZHH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6zhh]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZHH FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zhh OCA], [https://pdbe.org/6zhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zhh RCSB], [https://www.ebi.ac.uk/pdbsum/6zhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zhh ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=CE1:O-DODECANYL+OCTAETHYLENE+GLYCOL'>CE1</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">A3R04_02860 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1639 "Bacterium monocytogenes hominis" Nyfeldt 1932])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zhh OCA], [https://pdbe.org/6zhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zhh RCSB], [https://www.ebi.ac.uk/pdbsum/6zhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zhh ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Many bacteria export intracellular calcium using active transporters homologous to the sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA). Here we present three crystal structures of Ca(2+)-ATPase 1 from Listeria monocytogenes (LMCA1). Structures with BeF3(-) mimicking a phosphoenzyme state reveal a closed state, which is intermediate between the outward-open E2P and the proton-occluded E2-P* conformations known for SERCA. It suggests that LMCA1 in the E2P state is pre-organized for dephosphorylation upon Ca(2+) release, consistent with the rapid dephosphorylation observed in single-molecule studies. An arginine side-chain occupies the position equivalent to calcium binding site I in SERCA, leaving a single Ca(2+)-binding site in LMCA1, corresponding to SERCA site II. Observing no putative transport pathways dedicated to protons, we infer a direct proton counter transport through the Ca(2+) exchange pathways. The LMCA1 structures provide insight into the evolutionary divergence and conserved features of this important class of ion transporters.
		+
		+	The crystal structure of the Ca(2+)-ATPase 1 from Listeria monocytogenes reveals a pump primed for dephosphorylation.,Basse Hansen S, Dyla M, Neumann C, Meldgaard Hoegh Quistgaard E, Lauwring Andersen J, Kjaergaard M, Nissen P J Mol Biol. 2021 Apr 29:167015. doi: 10.1016/j.jmb.2021.167015. PMID:33933469<ref>PMID:33933469</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6zhh" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Basse Hansen S~~]]	+	[[Category: Andersen, J Lauwring]]
-	[[Category: Dyla M]]	+	[[Category: Dyla, M]]
-	[[Category: ~~Kjaergaard M~~]]	+	[[Category: Hansen, S Basse]]
-	[[Category: ~~Lauwring Andersen J~~]]	+	[[Category: Kjaergaard, M]]
-	[[Category: Neumann C]]	+	[[Category: Neumann, C]]
-	[[Category: Nissen P]]	+	[[Category: Nissen, P]]
-	[[Category: Quistgaard ~~EMH~~]]	+	[[Category: Quistgaard, E M.H]]
		+	[[Category: Listeria monocytogene]]
		+	[[Category: P-type atpase calcium pump]]
		+	[[Category: Transport protein]]

OCA at 10:07, 19 May 2021

OCA — Wed, 19 May 2021 10:07:04 GMT

←Older revision		Revision as of 10:07, 19 May 2021
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6zhh is ~~ON HOLD~~	+	==Ca2+-ATPase from Listeria Monocytogenes with G4 insertion.==
-		+	<StructureSection load='6zhh' size='340' side='right'caption='[[6zhh]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZHH FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zhh OCA], [https://pdbe.org/6zhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zhh RCSB], [https://www.ebi.ac.uk/pdbsum/6zhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zhh ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Basse Hansen S]]
		+	[[Category: Dyla M]]
		+	[[Category: Kjaergaard M]]
		+	[[Category: Lauwring Andersen J]]
		+	[[Category: Neumann C]]
		+	[[Category: Nissen P]]
		+	[[Category: Quistgaard EMH]]

OCA at 04:07, 28 April 2021

OCA — Wed, 28 Apr 2021 04:07:58 GMT

←Older revision		Revision as of 04:07, 28 April 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6zhh is ON HOLD ~~until Paper Publication~~	+	The entry 6zhh is ON HOLD

	Authors:		Authors:

OCA at 09:28, 29 July 2020

OCA — Wed, 29 Jul 2020 09:28:08 GMT

←Older revision		Revision as of 09:28, 29 July 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6zhh is ON HOLD	+	The entry 6zhh is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6zhh" [edit=sysop:move=sysop]

OCA — Wed, 08 Jul 2020 11:09:00 GMT

Protected "6zhh" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:09, 8 July 2020

OCA: New page: '''Unreleased structure''' The entry 6zhh is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 08 Jul 2020 11:08:59 GMT

New page: '''Unreleased structure''' The entry 6zhh is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6zhh is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]