6zmv - Revision history

OCA at 11:54, 1 February 2024

OCA — Thu, 01 Feb 2024 11:54:44 GMT

←Older revision		Revision as of 11:54, 1 February 2024
Line 3:		Line 3:
	<StructureSection load='6zmv' size='340' side='right'caption='[[6zmv]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='6zmv' size='340' side='right'caption='[[6zmv]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6zmv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Thelebolus_zukalii Thelebolus~~ zukalii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZMV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6zmv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichobolus_zukalii Trichobolus zukalii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZMV FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https:~~/~~/en.wikipedia.org/wiki/Lysozyme Lysozyme]~~, ~~with EC number [https~~:~~//www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zmv OCA], [https://pdbe.org/6zmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zmv RCSB], [https://www.ebi.ac.uk/pdbsum/6zmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zmv ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zmv OCA], [https://pdbe.org/6zmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zmv RCSB], [https://www.ebi.ac.uk/pdbsum/6zmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zmv ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A7S6G7I6_9PEZI A0A7S6G7I6_9PEZI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lysozyme]]~~	+	[[Category: Trichobolus zukalii]]
-	~~[[Category: Thelebolus~~ zukalii]]	+	[[Category: Blagova E]]
-	[[Category: Blagova, E]]	+	[[Category: Cohn MT]]
-	[[Category: Cohn~~, M T~~]]	+	[[Category: Davies GJ]]
-	[[Category: Davies~~, G J~~]]	+	[[Category: Gippert GP]]
-	[[Category: Gippert~~, G P~~]]	+	[[Category: Klausen M]]
-	[[Category: Klausen, M]]	+	[[Category: Ming L]]
-	[[Category: Ming, L]]	+	[[Category: Moroz OV]]
-	[[Category: Moroz~~, O V~~]]	+	[[Category: Nymand-Grarup S]]
-	[[Category: Nymand-Grarup, S]]	+	[[Category: Schmidt EGW]]
-	[[Category: Schmidt~~, E G.W~~]]	+	[[Category: Schnorr KM]]
-	[[Category: Schnorr~~, K M~~]]	+	[[Category: Skov LK]]
-	[[Category: Skov~~, L K~~]]	+	[[Category: Taylor E]]
-	[[Category: Taylor, E]]	+	[[Category: Turkenburg JP]]
-	[[Category: Turkenburg~~, J P~~]]	+	[[Category: Wilson KS]]
-	[[Category: Wilson~~, K S~~]]	+	[[Category: Ye L]]
-	[[Category: Ye, L]]	+
-	~~[[Category: Fungal]]~~	+
-	~~[[Category: Gh25]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Industrial application]]~~	+
-	~~[[Category: Muramidase]]~~	+
-	~~[[Category: Peptidoglycan cleavage~~]]	+

OCA at 07:07, 27 January 2022

OCA — Thu, 27 Jan 2022 07:07:20 GMT

←Older revision		Revision as of 07:07, 27 January 2022
Line 1:		Line 1:

	==Structure of muramidase from Trichobolus zukalii==		==Structure of muramidase from Trichobolus zukalii==
-	<StructureSection load='6zmv' size='340' side='right'caption='[[6zmv]]' scene=''>	+	<StructureSection load='6zmv' size='340' side='right'caption='[[6zmv]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZMV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6zmv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thelebolus_zukalii Thelebolus zukalii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZMV FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zmv OCA], [https://pdbe.org/6zmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zmv RCSB], [https://www.ebi.ac.uk/pdbsum/6zmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zmv ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zmv OCA], [https://pdbe.org/6zmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zmv RCSB], [https://www.ebi.ac.uk/pdbsum/6zmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zmv ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Muramidases/lysozymes hydrolyse the peptidoglycan component of the bacterial cell wall. They are found in many of the glycoside hydrolase (GH) families. Family GH25 contains muramidases/lysozymes, known as CH type lysozymes, as they were initially discovered in the Chalaropsis species of fungus. The characterized enzymes from GH25 exhibit both beta-1,4-N-acetyl- and beta-1,4-N,6-O-diacetylmuramidase activities, cleaving the beta-1,4-glycosidic bond between N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) moieties in the carbohydrate backbone of bacterial peptidoglycan. Here, a set of fungal GH25 muramidases were identified from a sequence search, cloned and expressed and screened for their ability to digest bacterial peptidoglycan, to be used in a commercial application in chicken feed. The screen identified the enzyme from Acremonium alcalophilum JCM 736 as a suitable candidate for this purpose and its relevant biochemical and biophysical and properties are described. We report the crystal structure of the A. alcalophilum enzyme at atomic, 0.78 A resolution, together with that of its homologue from Trichobolus zukalii at 1.4 A, and compare these with the structures of homologues. GH25 enzymes offer a new solution in animal feed applications such as for processing bacterial debris in the animal gut.
		+
		+	Fungal GH25 muramidases: New family members with applications in animal nutrition and a crystal structure at 0.78A resolution.,Moroz OV, Blagova E, Taylor E, Turkenburg JP, Skov LK, Gippert GP, Schnorr KM, Ming L, Ye L, Klausen M, Cohn MT, Schmidt EGW, Nymand-Grarup S, Davies GJ, Wilson KS PLoS One. 2021 Mar 12;16(3):e0248190. doi: 10.1371/journal.pone.0248190., eCollection 2021. PMID:33711051<ref>PMID:33711051</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6zmv" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Blagova E]]	+	[[Category: Lysozyme]]
-	[[Category: Cohn MT]]	+	[[Category: Thelebolus zukalii]]
-	[[Category: Davies GJ]]	+	[[Category: Blagova, E]]
-	[[Category: Gippert GP]]	+	[[Category: Cohn, M T]]
-	[[Category: Klausen M]]	+	[[Category: Davies, G J]]
-	[[Category: Ming L]]	+	[[Category: Gippert, G P]]
-	[[Category: Moroz OV]]	+	[[Category: Klausen, M]]
-	[[Category: Nymand-Grarup S]]	+	[[Category: Ming, L]]
-	[[Category: Schmidt ~~EGW~~]]	+	[[Category: Moroz, O V]]
-	[[Category: Schnorr KM]]	+	[[Category: Nymand-Grarup, S]]
-	[[Category: Skov LK]]	+	[[Category: Schmidt, E G.W]]
-	[[Category: Taylor E]]	+	[[Category: Schnorr, K M]]
-	[[Category: Turkenburg JP]]	+	[[Category: Skov, L K]]
-	[[Category: Wilson KS]]	+	[[Category: Taylor, E]]
-	[[Category: Ye L]]	+	[[Category: Turkenburg, J P]]
		+	[[Category: Wilson, K S]]
		+	[[Category: Ye, L]]
		+	[[Category: Fungal]]
		+	[[Category: Gh25]]
		+	[[Category: Hydrolase]]
		+	[[Category: Industrial application]]
		+	[[Category: Muramidase]]
		+	[[Category: Peptidoglycan cleavage]]

OCA at 09:50, 14 July 2021

OCA — Wed, 14 Jul 2021 09:50:31 GMT

←Older revision		Revision as of 09:50, 14 July 2021
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6zmv ~~is ON HOLD until Paper Publication~~	+	==Structure of muramidase from Trichobolus zukalii==
-		+	<StructureSection load='6zmv' size='340' side='right'caption='[[6zmv]]' scene=''>
-	~~Authors~~: ~~Moroz, O~~.V.~~, Blagova, E~~.~~, Taylor, E~~.~~, Turkenburg, J~~.P.~~, Skov, L~~.K.~~, Gippert, G.P~~., ~~Schnorr, K~~.M.~~, Ming, L~~., ~~Ye, L~~., ~~Klausen, M~~.~~, Cohn, M~~.T., ~~Schmidt, E~~.G.W., ~~Nymand~~-~~Grarup, S., Davies, G.J., Wilson, K.S~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZMV FirstGlance]. <br>
-	~~Description: Structure of muramidase from Trichobolus zukalii~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zmv OCA], [https://pdbe.org/6zmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zmv RCSB], [https://www.ebi.ac.uk/pdbsum/6zmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zmv ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Nymand-Grarup, S~~]]	+	__TOC__
-	[[Category: ~~Ming, L~~]]	+	</StructureSection>
-	[[Category: ~~Schnorr, K.M~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Wilson, K.S~~]]	+	[[Category: Blagova E]]
-	[[Category: ~~Ye, L~~]]	+	[[Category: Cohn MT]]
-	[[Category: ~~Taylor, E~~]]	+	[[Category: Davies GJ]]
-	[[Category: ~~Davies, G.J~~]]	+	[[Category: Gippert GP]]
-	[[Category: ~~Klausen, M~~]]	+	[[Category: Klausen M]]
-	[[Category: ~~Gippert, G.P~~]]	+	[[Category: Ming L]]
-	[[Category: ~~Skov, L.K~~]]	+	[[Category: Moroz OV]]
-	[[Category: ~~Turkenburg, J.P~~]]	+	[[Category: Nymand-Grarup S]]
-	[[Category: ~~Moroz, O.V~~]]	+	[[Category: Schmidt EGW]]
-	[[Category: ~~Schmidt, E.G.W~~]]	+	[[Category: Schnorr KM]]
-	[[Category: ~~Blagova, E~~]]	+	[[Category: Skov LK]]
-	[[Category: ~~Cohn, M.T~~]]	+	[[Category: Taylor E]]
		+	[[Category: Turkenburg JP]]
		+	[[Category: Wilson KS]]
		+	[[Category: Ye L]]

OCA at 03:55, 5 August 2020

OCA — Wed, 05 Aug 2020 03:55:45 GMT

←Older revision		Revision as of 03:55, 5 August 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6zmv is ON HOLD	+	The entry 6zmv is ON HOLD until Paper Publication

	Authors: Moroz, O.V., Blagova, E., Taylor, E., Turkenburg, J.P., Skov, L.K., Gippert, G.P., Schnorr, K.M., Ming, L., Ye, L., Klausen, M., Cohn, M.T., Schmidt, E.G.W., Nymand-Grarup, S., Davies, G.J., Wilson, K.S.		Authors: Moroz, O.V., Blagova, E., Taylor, E., Turkenburg, J.P., Skov, L.K., Gippert, G.P., Schnorr, K.M., Ming, L., Ye, L., Klausen, M., Cohn, M.T., Schmidt, E.G.W., Nymand-Grarup, S., Davies, G.J., Wilson, K.S.
Line 7:		Line 7:
	Description: Structure of muramidase from Trichobolus zukalii		Description: Structure of muramidase from Trichobolus zukalii
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Nymand-Grarup, S]]
		+	[[Category: Ming, L]]
	[[Category: Schnorr, K.M]]		[[Category: Schnorr, K.M]]
	[[Category: Wilson, K.S]]		[[Category: Wilson, K.S]]
	[[Category: Ye, L]]		[[Category: Ye, L]]
	[[Category: Taylor, E]]		[[Category: Taylor, E]]
-	[[Category: Skov, L.K]]
-	[[Category: Schmidt, E.G.W]]
-	[[Category: Blagova, E]]
-	[[Category: Nymand-Grarup, S]]
-	[[Category: Ming, L]]
	[[Category: Davies, G.J]]		[[Category: Davies, G.J]]
	[[Category: Klausen, M]]		[[Category: Klausen, M]]
	[[Category: Gippert, G.P]]		[[Category: Gippert, G.P]]
		+	[[Category: Skov, L.K]]
	[[Category: Turkenburg, J.P]]		[[Category: Turkenburg, J.P]]
	[[Category: Moroz, O.V]]		[[Category: Moroz, O.V]]
		+	[[Category: Schmidt, E.G.W]]
		+	[[Category: Blagova, E]]
	[[Category: Cohn, M.T]]		[[Category: Cohn, M.T]]

OCA: Protected "6zmv" [edit=sysop:move=sysop]

OCA — Wed, 22 Jul 2020 08:02:11 GMT

Protected "6zmv" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:02, 22 July 2020

OCA: New page: '''Unreleased structure''' The entry 6zmv is ON HOLD Authors: Moroz, O.V., Blagova, E., Taylor, E., Turkenburg, J.P., Skov, L.K., Gippert, G.P., Schnorr, K.M., Ming, L., Ye, L., Klausen...

OCA — Wed, 22 Jul 2020 08:02:09 GMT

New page: '''Unreleased structure''' The entry 6zmv is ON HOLD Authors: Moroz, O.V., Blagova, E., Taylor, E., Turkenburg, J.P., Skov, L.K., Gippert, G.P., Schnorr, K.M., Ming, L., Ye, L., Klausen...

New page

'''Unreleased structure'''

The entry 6zmv is ON HOLD

Authors: Moroz, O.V., Blagova, E., Taylor, E., Turkenburg, J.P., Skov, L.K., Gippert, G.P., Schnorr, K.M., Ming, L., Ye, L., Klausen, M., Cohn, M.T., Schmidt, E.G.W., Nymand-Grarup, S., Davies, G.J., Wilson, K.S.

Description: Structure of muramidase from Trichobolus zukalii
[[Category: Unreleased Structures]]
[[Category: Schnorr, K.M]]
[[Category: Wilson, K.S]]
[[Category: Ye, L]]
[[Category: Taylor, E]]
[[Category: Skov, L.K]]
[[Category: Schmidt, E.G.W]]
[[Category: Blagova, E]]
[[Category: Nymand-Grarup, S]]
[[Category: Ming, L]]
[[Category: Davies, G.J]]
[[Category: Klausen, M]]
[[Category: Gippert, G.P]]
[[Category: Turkenburg, J.P]]
[[Category: Moroz, O.V]]
[[Category: Cohn, M.T]]