OCA at 12:47, 26 July 2023

OCA — Wed, 26 Jul 2023 12:47:19 GMT

←Older revision		Revision as of 12:47, 26 July 2023
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-	====	+	==Racemic compound of RNA duplexes.==
-	<StructureSection load='6zr1' size='340' side='right'caption='[[6zr1]]' scene=''>	+	<StructureSection load='6zr1' size='340' side='right'caption='[[6zr1]], [[Resolution\|resolution]] 1.53Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6zr1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZR1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZR1 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zr1 OCA], [https://pdbe.org/6zr1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zr1 RCSB], [https://www.ebi.ac.uk/pdbsum/6zr1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zr1 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.528Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0C:L-CYTIDINE-5-MONOPHOSPHATE'>0C</scene>, <scene name='pdbligand=0G:L-GUANOSINE-5-MONOPHOSPHATE'>0G</scene>, <scene name='pdbligand=0U:L-URIDINE-5-MONOPHOSPHATE'>0U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zr1 OCA], [https://pdbe.org/6zr1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zr1 RCSB], [https://www.ebi.ac.uk/pdbsum/6zr1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zr1 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Explaining the origin of the homochirality of biological molecules requires a mechanism of disrupting the natural equilibrium between enantiomers and amplifying the initial imbalance to significant levels. Authors of existing models have sought an explanation in the parity-breaking weak nuclear force, in some selectively acting external factor, or in random fluctuations that subsequently became amplified by an autocatalytic process. We have obtained crystals in which l- and d-enantiomers of short RNA duplexes assemble in an asymmetric manner. These enantiomers make different lattice contacts and have different exposures to water and metal ions present in the crystal. Apparently, asymmetry between enantiomers can arise upon their mutual interactions and then propagate via crystallization. Asymmetric racemic compounds are worth considering as possible factors in symmetry breaking and enantioenrichment that took place in the early biosphere.
		+
		+	Broken symmetry between RNA enantiomers in a crystal lattice.,Kiliszek A, Blaszczyk L, Bejger M, Rypniewski W Nucleic Acids Res. 2021 Dec 2;49(21):12535-12539. doi: 10.1093/nar/gkab480. PMID:34107036<ref>PMID:34107036</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6zr1" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Thermus thermophilus]]
		+	[[Category: Rypniewski W]]

OCA at 09:16, 26 May 2021

OCA — Wed, 26 May 2021 09:16:47 GMT

←Older revision		Revision as of 09:16, 26 May 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 6zr1 ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='6zr1' size='340' side='right'caption='[[6zr1]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zr1 OCA], [https://pdbe.org/6zr1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zr1 RCSB], [https://www.ebi.ac.uk/pdbsum/6zr1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zr1 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 03:56, 14 October 2020

OCA — Wed, 14 Oct 2020 03:56:44 GMT

←Older revision		Revision as of 03:56, 14 October 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6zr1 is ON HOLD	+	The entry 6zr1 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6zr1" [edit=sysop:move=sysop]

OCA — Wed, 22 Jul 2020 08:15:06 GMT

Protected "6zr1" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:15, 22 July 2020

OCA: New page: '''Unreleased structure''' The entry 6zr1 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 22 Jul 2020 08:15:04 GMT

New page: '''Unreleased structure''' The entry 6zr1 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6zr1 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

6zr1 - Revision history

OCA at 12:47, 26 July 2023

OCA at 09:16, 26 May 2021

OCA at 03:56, 14 October 2020

OCA: Protected "6zr1" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 6zr1 is ON HOLD Authors: Description: Category: Unreleased Structures