6zx8 - Revision history

OCA at 12:47, 26 July 2023

OCA — Wed, 26 Jul 2023 12:47:28 GMT

←Older revision		Revision as of 12:47, 26 July 2023
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-	====	+	==Racemic compound of RNA duplexes.==
-	<StructureSection load='6zx8' size='340' side='right'caption='[[6zx8]]' scene=''>	+	<StructureSection load='6zx8' size='340' side='right'caption='[[6zx8]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6zx8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZX8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zx8 OCA], [https://pdbe.org/6zx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zx8 RCSB], [https://www.ebi.ac.uk/pdbsum/6zx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zx8 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.981Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0C:L-CYTIDINE-5-MONOPHOSPHATE'>0C</scene>, <scene name='pdbligand=0G:L-GUANOSINE-5-MONOPHOSPHATE'>0G</scene>, <scene name='pdbligand=0U:L-URIDINE-5-MONOPHOSPHATE'>0U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zx8 OCA], [https://pdbe.org/6zx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zx8 RCSB], [https://www.ebi.ac.uk/pdbsum/6zx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zx8 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Explaining the origin of the homochirality of biological molecules requires a mechanism of disrupting the natural equilibrium between enantiomers and amplifying the initial imbalance to significant levels. Authors of existing models have sought an explanation in the parity-breaking weak nuclear force, in some selectively acting external factor, or in random fluctuations that subsequently became amplified by an autocatalytic process. We have obtained crystals in which l- and d-enantiomers of short RNA duplexes assemble in an asymmetric manner. These enantiomers make different lattice contacts and have different exposures to water and metal ions present in the crystal. Apparently, asymmetry between enantiomers can arise upon their mutual interactions and then propagate via crystallization. Asymmetric racemic compounds are worth considering as possible factors in symmetry breaking and enantioenrichment that took place in the early biosphere.
		+
		+	Broken symmetry between RNA enantiomers in a crystal lattice.,Kiliszek A, Blaszczyk L, Bejger M, Rypniewski W Nucleic Acids Res. 2021 Dec 2;49(21):12535-12539. doi: 10.1093/nar/gkab480. PMID:34107036<ref>PMID:34107036</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6zx8" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Thermus thermophilus]]
		+	[[Category: Rypniewski W]]

OCA at 09:16, 26 May 2021

OCA — Wed, 26 May 2021 09:16:54 GMT

←Older revision		Revision as of 09:16, 26 May 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 6zx8 ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='6zx8' size='340' side='right'caption='[[6zx8]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zx8 OCA], [https://pdbe.org/6zx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zx8 RCSB], [https://www.ebi.ac.uk/pdbsum/6zx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zx8 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 03:57, 14 October 2020

OCA — Wed, 14 Oct 2020 03:57:05 GMT

←Older revision		Revision as of 03:57, 14 October 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6zx8 is ON HOLD	+	The entry 6zx8 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 08:35, 23 September 2020

OCA — Wed, 23 Sep 2020 08:35:41 GMT

←Older revision		Revision as of 08:35, 23 September 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6zx8 is ON HOLD ~~until sometime in the future~~	+	The entry 6zx8 is ON HOLD

	Authors:		Authors:

OCA at 08:14, 12 August 2020

OCA — Wed, 12 Aug 2020 08:14:00 GMT

←Older revision		Revision as of 08:14, 12 August 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6zx8 is ON HOLD	+	The entry 6zx8 is ON HOLD until sometime in the future

	Authors:		Authors:

OCA: Protected "6zx8" [edit=sysop:move=sysop]

OCA — Wed, 05 Aug 2020 04:02:58 GMT

Protected "6zx8" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:02, 5 August 2020

OCA: New page: '''Unreleased structure''' The entry 6zx8 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 05 Aug 2020 04:02:57 GMT

New page: '''Unreleased structure''' The entry 6zx8 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6zx8 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]