OCA at 09:06, 5 May 2021

OCA — Wed, 05 May 2021 09:06:16 GMT

←Older revision		Revision as of 09:06, 5 May 2021
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	==rsGreen0.7-K206A-H148S in the green-on state==		==rsGreen0.7-K206A-H148S in the green-on state==
-	<StructureSection load='7a8h' size='340' side='right'caption='[[7a8h]]' scene=''>	+	<StructureSection load='7a8h' size='340' side='right'caption='[[7a8h]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A8H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7a8h]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeqvi Aeqvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A8H FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a8h OCA], [https://pdbe.org/7a8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a8h RCSB], [https://www.ebi.ac.uk/pdbsum/7a8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a8h ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CRO:{2-[(1R,2R)-1-AMINO-2-HYDROXYPROPYL]-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>CRO</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4xow\|4xow]], [[4xov\|4xov]]</div></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gfp ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6100 AEQVI])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a8h OCA], [https://pdbe.org/7a8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a8h RCSB], [https://www.ebi.ac.uk/pdbsum/7a8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a8h ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Anisotropic environments can drastically alter the spectroscopy and photochemistry of molecules, leading to complex structure-function relationships. We examined this using fluorescent proteins as easy-to-modify model systems. Starting from a single scaffold, we have developed a range of 27 photochromic fluorescent proteins that cover a broad range of spectroscopic properties, including the determination of 43 crystal structures. Correlation and principal component analysis confirmed the complex relationship between structure and spectroscopy, but also allowed us to identify consistent trends and to relate these to the spatial organization. We find that changes in spectroscopic properties can come about through multiple underlying mechanisms, of which polarity, hydrogen bonding and presence of water molecules are key modulators. We anticipate that our findings and rich structure/spectroscopy dataset can open opportunities for the development and evaluation of new and existing protein engineering methods.
		+
		+	Structure-Function Dataset Reveals Environment Effects within a Fluorescent Protein Model System.,De Zitter E, Hugelier S, Duwe S, Vandenberg W, Tebo AG, Van Meervelt L, Dedecker P Angew Chem Int Ed Engl. 2021 Feb 4. doi: 10.1002/anie.202015201. PMID:33543524<ref>PMID:33543524</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7a8h" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Aeqvi]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: De Zitter E]]	+	[[Category: Dedecker, P]]
-	[[Category: ~~Dedecker P~~]]	+	[[Category: Meervelt, L Van]]
-	[[Category: ~~Van Meervelt L~~]]	+	[[Category: Zitter, E De]]
		+	[[Category: Fluorescent protein]]
		+	[[Category: Reversible photoswitchable fluorescent protein]]

OCA at 10:00, 17 February 2021

OCA — Wed, 17 Feb 2021 10:00:08 GMT

←Older revision		Revision as of 10:00, 17 February 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7a8h is ~~ON HOLD~~	+	==rsGreen0.7-K206A-H148S in the green-on state==
-		+	<StructureSection load='7a8h' size='340' side='right'caption='[[7a8h]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A8H FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a8h OCA], [https://pdbe.org/7a8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a8h RCSB], [https://www.ebi.ac.uk/pdbsum/7a8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a8h ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: De Zitter E]]
		+	[[Category: Dedecker P]]
		+	[[Category: Van Meervelt L]]

OCA: Protected "7a8h" [edit=sysop:move=sysop]

OCA — Wed, 09 Sep 2020 07:15:21 GMT

Protected "7a8h" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:15, 9 September 2020

OCA: New page: '''Unreleased structure''' The entry 7a8h is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 09 Sep 2020 07:15:18 GMT

New page: '''Unreleased structure''' The entry 7a8h is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7a8h is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

7a8h - Revision history

OCA at 09:06, 5 May 2021

OCA at 10:00, 17 February 2021

OCA: Protected "7a8h" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7a8h is ON HOLD Authors: Description: Category: Unreleased Structures