OCA at 12:47, 26 July 2023

OCA — Wed, 26 Jul 2023 12:47:33 GMT

←Older revision		Revision as of 12:47, 26 July 2023
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-	====	+	==Racemic compound of RNA duplexes.==
-	<StructureSection load='7a9o' size='340' side='right'caption='[[7a9o]]' scene=''>	+	<StructureSection load='7a9o' size='340' side='right'caption='[[7a9o]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7a9o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A9O FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a9o OCA], [https://pdbe.org/7a9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a9o RCSB], [https://www.ebi.ac.uk/pdbsum/7a9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a9o ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.601Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0C:L-CYTIDINE-5-MONOPHOSPHATE'>0C</scene>, <scene name='pdbligand=0G:L-GUANOSINE-5-MONOPHOSPHATE'>0G</scene>, <scene name='pdbligand=0U:L-URIDINE-5-MONOPHOSPHATE'>0U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a9o OCA], [https://pdbe.org/7a9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a9o RCSB], [https://www.ebi.ac.uk/pdbsum/7a9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a9o ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Explaining the origin of the homochirality of biological molecules requires a mechanism of disrupting the natural equilibrium between enantiomers and amplifying the initial imbalance to significant levels. Authors of existing models have sought an explanation in the parity-breaking weak nuclear force, in some selectively acting external factor, or in random fluctuations that subsequently became amplified by an autocatalytic process. We have obtained crystals in which l- and d-enantiomers of short RNA duplexes assemble in an asymmetric manner. These enantiomers make different lattice contacts and have different exposures to water and metal ions present in the crystal. Apparently, asymmetry between enantiomers can arise upon their mutual interactions and then propagate via crystallization. Asymmetric racemic compounds are worth considering as possible factors in symmetry breaking and enantioenrichment that took place in the early biosphere.
		+
		+	Broken symmetry between RNA enantiomers in a crystal lattice.,Kiliszek A, Blaszczyk L, Bejger M, Rypniewski W Nucleic Acids Res. 2021 Dec 2;49(21):12535-12539. doi: 10.1093/nar/gkab480. PMID:34107036<ref>PMID:34107036</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7a9o" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Thermus thermophilus]]
		+	[[Category: Rypniewski W]]

OCA at 09:17, 26 May 2021

OCA — Wed, 26 May 2021 09:17:07 GMT

←Older revision		Revision as of 09:17, 26 May 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7a9o ~~is ON HOLD~~	+	====
-		+	<StructureSection load='7a9o' size='340' side='right'caption='[[7a9o]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a9o OCA], [https://pdbe.org/7a9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a9o RCSB], [https://www.ebi.ac.uk/pdbsum/7a9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a9o ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA: Protected "7a9o" [edit=sysop:move=sysop]

OCA — Wed, 09 Sep 2020 07:20:45 GMT

Protected "7a9o" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:20, 9 September 2020

OCA: New page: '''Unreleased structure''' The entry 7a9o is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 09 Sep 2020 07:20:43 GMT

New page: '''Unreleased structure''' The entry 7a9o is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7a9o is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

7a9o - Revision history

OCA at 12:47, 26 July 2023

OCA at 09:17, 26 May 2021

OCA: Protected "7a9o" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7a9o is ON HOLD Authors: Description: Category: Unreleased Structures