7awz - Revision history

OCA at 12:18, 1 February 2024

OCA — Thu, 01 Feb 2024 12:18:04 GMT

←Older revision		Revision as of 12:18, 1 February 2024
Line 3:		Line 3:
	<StructureSection load='7awz' size='340' side='right'caption='[[7awz]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='7awz' size='340' side='right'caption='[[7awz]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7awz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Synthetic_construct_sequences~~ Synthetic construct ~~sequences~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AWZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7awz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AWZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7awz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7awz OCA], [https://pdbe.org/7awz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7awz RCSB], [https://www.ebi.ac.uk/pdbsum/7awz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7awz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7awz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7awz OCA], [https://pdbe.org/7awz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7awz RCSB], [https://www.ebi.ac.uk/pdbsum/7awz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7awz ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Synthetic construct ~~sequences~~]]	+	[[Category: Synthetic construct]]
-	[[Category: Mylemans, B]]	+	[[Category: Mylemans B]]
-	[[Category: Voet~~, A R.D]]~~	+	[[Category: Voet ARD]]
-	~~[[Category: Beta-propeller]]~~	+
-	~~[[Category: Computational design]]~~	+
-	~~[[Category: De novo protein~~]]	+

OCA at 10:04, 14 July 2021

OCA — Wed, 14 Jul 2021 10:04:11 GMT

←Older revision		Revision as of 10:04, 14 July 2021
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7awz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7awz OCA], [https://pdbe.org/7awz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7awz RCSB], [https://www.ebi.ac.uk/pdbsum/7awz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7awz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7awz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7awz OCA], [https://pdbe.org/7awz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7awz RCSB], [https://www.ebi.ac.uk/pdbsum/7awz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7awz ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Recent years have seen an increase in the development of computational proteins, including symmetric ones. A ninefold-symmetric beta-propeller protein named Cake has recently been developed. Here, attempts were made to further engineer this protein into a threefold-symmetric nine-bladed propeller using computational design. Two nine-bladed propeller proteins were designed, named Scone-E and Scone-R. Crystallography, however, revealed the structure of both designs to adopt an eightfold conformation with distorted termini, leading to a pseudo-symmetric protein. One of the proteins could only be crystallized upon the addition of a polyoxometalate, highlighting the usefulness of these molecules as crystallization additives.
		+
		+	Crystal structures of Scone: pseudosymmetric folding of a symmetric designer protein.,Mylemans B, Killian T, Vandebroek L, Van Meervelt L, Tame JRH, Parac-Vogt TN, Voet ARD Acta Crystallogr D Struct Biol. 2021 Jul 1;77(Pt 7):933-942. doi:, 10.1107/S2059798321005787. Epub 2021 Jun 18. PMID:34196619<ref>PMID:34196619</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7awz" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 03:47, 2 July 2021

OCA — Fri, 02 Jul 2021 03:47:52 GMT

←Older revision		Revision as of 03:47, 2 July 2021
Line 1:		Line 1:

	==Crystal structure of the computationally designed Scone-E protein==		==Crystal structure of the computationally designed Scone-E protein==
-	<StructureSection load='7awz' size='340' side='right'caption='[[7awz]]' scene=''>	+	<StructureSection load='7awz' size='340' side='right'caption='[[7awz]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AWZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=7AWZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7awz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AWZ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7awz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7awz OCA], [~~http~~://pdbe.org/7awz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7awz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7awz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7awz ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7awz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7awz OCA], [https://pdbe.org/7awz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7awz RCSB], [https://www.ebi.ac.uk/pdbsum/7awz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7awz ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Mylemans B]]	+	[[Category: Synthetic construct sequences]]
-	[[Category: Voet ~~ARD~~]]	+	[[Category: Mylemans, B]]
		+	[[Category: Voet, A R.D]]
		+	[[Category: Beta-propeller]]
		+	[[Category: Computational design]]
		+	[[Category: De novo protein]]

OCA at 05:53, 20 January 2021

OCA — Wed, 20 Jan 2021 05:53:08 GMT

←Older revision		Revision as of 05:53, 20 January 2021
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7awz ~~is ON HOLD~~	+	==Crystal structure of the computationally designed Scone-E protein==
-		+	<StructureSection load='7awz' size='340' side='right'caption='[[7awz]]' scene=''>
-	~~Authors~~: ~~Mylemans~~, B., ~~Voet~~, A.R.D.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AWZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7AWZ FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of the computationally designed Scone~~-~~E protein~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7awz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7awz OCA], [http://pdbe.org/7awz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7awz RCSB], [http://www.ebi.ac.uk/pdbsum/7awz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7awz ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Mylemans, B]]	+	__TOC__
-	[[Category: Voet~~, A.R.D~~]]	+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Mylemans B]]
		+	[[Category: Voet ARD]]

OCA: Protected "7awz" [edit=sysop:move=sysop]

OCA — Wed, 18 Nov 2020 07:54:54 GMT

Protected "7awz" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:54, 18 November 2020

OCA: New page: '''Unreleased structure''' The entry 7awz is ON HOLD Authors: Mylemans, B., Voet, A.R.D. Description: Crystal structure of the computationally designed Scone-E protein [[Category: Unre...

OCA — Wed, 18 Nov 2020 07:54:53 GMT

New page: '''Unreleased structure''' The entry 7awz is ON HOLD Authors: Mylemans, B., Voet, A.R.D. Description: Crystal structure of the computationally designed Scone-E protein [[Category: Unre...

New page

'''Unreleased structure'''

The entry 7awz is ON HOLD

Authors: Mylemans, B., Voet, A.R.D.

Description: Crystal structure of the computationally designed Scone-E protein
[[Category: Unreleased Structures]]
[[Category: Mylemans, B]]
[[Category: Voet, A.R.D]]