7c8p - Revision history

OCA at 16:00, 29 November 2023

OCA — Wed, 29 Nov 2023 16:00:01 GMT

←Older revision		Revision as of 16:00, 29 November 2023
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	==Structural and functional characterization of human group A rotavirus P[25] VP8*==		==Structural and functional characterization of human group A rotavirus P[25] VP8*==
-	<StructureSection load='7c8p' size='340' side='right'caption='[[7c8p]]' scene=''>	+	<StructureSection load='7c8p' size='340' side='right'caption='[[7c8p]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C8P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C8P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7c8p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rotavirus_A Rotavirus A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C8P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C8P FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c8p OCA], [https://pdbe.org/7c8p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c8p RCSB], [https://www.ebi.ac.uk/pdbsum/7c8p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c8p ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c8p OCA], [https://pdbe.org/7c8p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c8p RCSB], [https://www.ebi.ac.uk/pdbsum/7c8p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c8p ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/M1GR78_9VIRU M1GR78_9VIRU]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rotavirus (RV) is a common cause of acute gastroenteritis in young children. While P[8] and P[4] are the most prevalent RV genotypes in humans, other genotypes are also reported in human infections occasionally, including human P[25]. The glycan binding and structural characteristics of human P[25] were explored in our study. Human P[25] VP8* recognized type A histo-blood group antigen (HBGA) in the glycan microarray/oligosaccharide binding assay and could specifically hemagglutinate type A blood cells. Moreover, the P[25] VP8* structure was determined at 2.6 A, revealing a similar conformation and a conserved putative glycan binding site as that of P[14] VP8. This study provided further knowledge of the glycan binding and structural features of P[25] RV VP8, promoting our understanding of the infection, prevalence, and host range of the P[III] RVs.
		+
		+	Human group A rotavirus P[25] VP8* specifically binds to A-type histo-blood group antigen.,Li D, Wang M, Qi J, Zhang Q, Wang H, Pang L, Sun X, Duan Z Virology. 2021 Mar;555:56-63. doi: 10.1016/j.virol.2020.12.016. Epub 2021 Jan 5. PMID:33453651<ref>PMID:33453651</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7c8p" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Rotavirus A]]
	[[Category: Dandi L]]		[[Category: Dandi L]]
	[[Category: Duan Z]]		[[Category: Duan Z]]

OCA at 06:46, 14 April 2021

OCA — Wed, 14 Apr 2021 06:46:13 GMT

←Older revision		Revision as of 06:46, 14 April 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7c8p ~~is ON HOLD until Paper Publication~~	+	==Structural and functional characterization of human group A rotavirus P[25] VP8*==
-		+	<StructureSection load='7c8p' size='340' side='right'caption='[[7c8p]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C8P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C8P FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c8p OCA], [https://pdbe.org/7c8p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c8p RCSB], [https://www.ebi.ac.uk/pdbsum/7c8p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c8p ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Dandi L]]
		+	[[Category: Duan Z]]

OCA at 11:22, 8 July 2020

OCA — Wed, 08 Jul 2020 11:22:20 GMT

←Older revision		Revision as of 11:22, 8 July 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7c8p is ON HOLD	+	The entry 7c8p is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7c8p" [edit=sysop:move=sysop]

OCA — Wed, 10 Jun 2020 05:18:39 GMT

Protected "7c8p" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:18, 10 June 2020

OCA: New page: '''Unreleased structure''' The entry 7c8p is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 10 Jun 2020 05:18:38 GMT

New page: '''Unreleased structure''' The entry 7c8p is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7c8p is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]