7cas - Revision history

OCA at 16:01, 29 November 2023

OCA — Wed, 29 Nov 2023 16:01:29 GMT

←Older revision		Revision as of 16:01, 29 November 2023
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	<StructureSection load='7cas' size='340' side='right'caption='[[7cas]], [[Resolution\|resolution]] 2.28Å' scene=''>		<StructureSection load='7cas' size='340' side='right'caption='[[7cas]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7cas]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Metma Metma~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CAS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7cas]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_mazei_Go1 Methanosarcina mazei Go1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CAS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.28Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cas OCA], [https://pdbe.org/7cas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cas RCSB], [https://www.ebi.ac.uk/pdbsum/7cas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cas ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cas OCA], [https://pdbe.org/7cas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cas RCSB], [https://www.ebi.ac.uk/pdbsum/7cas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cas ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0F8R9A0_METMZ A0A0F8R9A0_METMZ]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Metma~~]]	+	[[Category: Methanosarcina mazei Go1]]
-	[[Category: Hemmi, H]]	+	[[Category: Hemmi H]]
-	[[Category: Unno, H]]	+	[[Category: Unno H]]
-	~~[[Category: Archaea]]~~	+
-	~~[[Category: Cis-prenyltransferase]]~~	+
-	~~[[Category: Isoprenoid]]~~	+
-	~~[[Category: Methanosarcina mazei]]~~	+
-	~~[[Category: Mm_0014]]~~	+
-	~~[[Category: Ppi]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 10:05, 14 July 2021

OCA — Wed, 14 Jul 2021 10:05:25 GMT

←Older revision		Revision as of 10:05, 14 July 2021
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	<StructureSection load='7cas' size='340' side='right'caption='[[7cas]], [[Resolution\|resolution]] 2.28Å' scene=''>		<StructureSection load='7cas' size='340' side='right'caption='[[7cas]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7cas]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CAS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7cas]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Metma Metma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CAS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cas OCA], [https://pdbe.org/7cas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cas RCSB], [https://www.ebi.ac.uk/pdbsum/7cas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cas ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cas OCA], [https://pdbe.org/7cas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cas RCSB], [https://www.ebi.ac.uk/pdbsum/7cas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cas ProSAT]</span></td></tr>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Metma]]
	[[Category: Hemmi, H]]		[[Category: Hemmi, H]]
	[[Category: Unno, H]]		[[Category: Unno, H]]

OCA at 09:09, 5 May 2021

OCA — Wed, 05 May 2021 09:09:45 GMT

←Older revision		Revision as of 09:09, 5 May 2021
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	==Versatile cis-prenyltransferase MM_0014 from Methanosarcina mazei (crystal type: free+PPi)==		==Versatile cis-prenyltransferase MM_0014 from Methanosarcina mazei (crystal type: free+PPi)==
-	<StructureSection load='7cas' size='340' side='right'caption='[[7cas]]' scene=''>	+	<StructureSection load='7cas' size='340' side='right'caption='[[7cas]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CAS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7cas]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CAS FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cas OCA], [https://pdbe.org/7cas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cas RCSB], [https://www.ebi.ac.uk/pdbsum/7cas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cas ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cas OCA], [https://pdbe.org/7cas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cas RCSB], [https://www.ebi.ac.uk/pdbsum/7cas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cas ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Polyprenyl groups, products of isoprenoid metabolism, are utilized in peptidoglycan biosynthesis, protein N-glycosylation, and other processes. These groups are formed by cis-prenyltransferases, which use allylic prenyl pyrophosphates as prenyl-donors to catalyze the C-prenylation of the general acceptor substrate, isopentenyl pyrophosphate. Repetition of this reaction forms (Z,E-mixed)-polyprenyl pyrophosphates, which are converted later into glycosyl carrier lipids, such as undecaprenyl phosphate and dolichyl phosphate. MM_0014 from the methanogenic archaeon Methanosarcina mazei is known as a versatile cis-prenyltransferase that accepts both isopentenyl pyrophosphate and dimethylallyl pyrophosphate as acceptor substrates. To learn more about this enzyme's catalytic activity, we determined the X-ray crystal structures of MM_0014 in the presence or absence of these substrates. Surprisingly, one structure revealed a complex with O-prenylglycerol, suggesting that the enzyme catalyzed the prenylation of glycerol contained in the crystallization buffer. Further analyses confirmed that the enzyme could catalyze the O-prenylation of small alcohols, such as 2-propanol, expanding our understanding of the catalytic ability of cis-prenyltransferases.
		+
		+	A versatile cis-prenyltransferase from Methanosarcina mazei catalyzes both C- and O-prenylations.,Okada M, Unno H, Emi KI, Matsumoto M, Hemmi H J Biol Chem. 2021 Apr 16:100679. doi: 10.1016/j.jbc.2021.100679. PMID:33872599<ref>PMID:33872599</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7cas" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hemmi H]]	+	[[Category: Hemmi, H]]
-	[[Category: Unno H]]	+	[[Category: Unno, H]]
		+	[[Category: Archaea]]
		+	[[Category: Cis-prenyltransferase]]
		+	[[Category: Isoprenoid]]
		+	[[Category: Methanosarcina mazei]]
		+	[[Category: Mm_0014]]
		+	[[Category: Ppi]]
		+	[[Category: Transferase]]

OCA at 05:20, 28 April 2021

OCA — Wed, 28 Apr 2021 05:20:16 GMT

←Older revision		Revision as of 05:20, 28 April 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7cas ~~is ON HOLD until Paper Publication~~	+	==Versatile cis-prenyltransferase MM_0014 from Methanosarcina mazei (crystal type: free+PPi)==
-		+	<StructureSection load='7cas' size='340' side='right'caption='[[7cas]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CAS FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cas OCA], [https://pdbe.org/7cas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cas RCSB], [https://www.ebi.ac.uk/pdbsum/7cas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cas ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Hemmi H]]
		+	[[Category: Unno H]]

OCA at 11:23, 8 July 2020

OCA — Wed, 08 Jul 2020 11:23:28 GMT

←Older revision		Revision as of 11:23, 8 July 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7cas is ON HOLD	+	The entry 7cas is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7cas" [edit=sysop:move=sysop]

OCA — Wed, 17 Jun 2020 09:02:46 GMT

Protected "7cas" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:02, 17 June 2020

OCA: New page: '''Unreleased structure''' The entry 7cas is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 17 Jun 2020 09:02:44 GMT

New page: '''Unreleased structure''' The entry 7cas is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7cas is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]