7cv0 - Revision history

OCA at 16:16, 29 November 2023

OCA — Wed, 29 Nov 2023 16:16:50 GMT

←Older revision		Revision as of 16:16, 29 November 2023
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	==Crystal structure of B. halodurans NiaR in apo form==		==Crystal structure of B. halodurans NiaR in apo form==
-	<StructureSection load='7cv0' size='340' side='right'caption='[[7cv0]]' scene=''>	+	<StructureSection load='7cv0' size='340' side='right'caption='[[7cv0]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CV0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=7CV0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7cv0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans_C-125 Alkalihalobacillus halodurans C-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CV0 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7cv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cv0 OCA], [~~http~~://pdbe.org/7cv0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7cv0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7cv0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7cv0 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.998Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cv0 OCA], [https://pdbe.org/7cv0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cv0 RCSB], [https://www.ebi.ac.uk/pdbsum/7cv0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cv0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9KDJ7_HALH5 Q9KDJ7_HALH5]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The niacin-responsive repressor, NiaR, is transcriptional repressor of certain nicotinamide adenine dinucleotide (NAD) biosynthetic genes in response to an increase in niacin levels. NAD is a vital molecule involved in various cellular redox reactions as an electron donor or electron acceptor. The NiaR family is conserved broadly in the Bacillus/Clostridium group, as well as in the Fusobacteria and Thermotogales lineages. The NiaR structure consists of two domains: an N-terminal DNA-binding domain, and a C-terminal regulation domain containing a metal-binding site. In this paper, we report the crystal structures of apo and niacin-bound forms of NiaR from Bacillus halodurans (BhNiaR). The analysis of metal-binding and niacin-binding sites through the apo and niacin-bound structures is described. Each N- and C-terminal domain structure of BhNiaR is almost identical with NiaR from Thermotoga maritima, but the overall domain arrangement is quite different. A zinc ion is fully occupied in each subunit with well-conserved residues in the C-terminal domain. Niacin is also located at a hydrophobic pocket near the zinc ion in the C-terminal domain.
		+
		+	Structural analysis and insight into effector binding of the niacin-responsive repressor NiaR from Bacillus halodurans.,Lee DW, Park YW, Lee MY, Jeong KH, Lee JY Sci Rep. 2020 Dec 3;10(1):21039. doi: 10.1038/s41598-020-78148-x. PMID:33273654<ref>PMID:33273654</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7cv0" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Alkalihalobacillus halodurans C-125]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Jeong KH]]		[[Category: Jeong KH]]

OCA at 12:35, 16 December 2020

OCA — Wed, 16 Dec 2020 12:35:10 GMT

←Older revision		Revision as of 12:35, 16 December 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 7cv0 ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of B. halodurans NiaR in apo form==
-		+	<StructureSection load='7cv0' size='340' side='right'caption='[[7cv0]]' scene=''>
-	~~Authors~~: ~~Lee, J~~.Y., ~~Lee, D~~.W., ~~Park~~, Y.W., ~~Lee, M~~.Y., ~~Jeong, K~~.H.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CV0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7CV0 FirstGlance]. <br>
-	~~Description: Crystal structure of B. halodurans NiaR in apo form~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7cv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cv0 OCA], [http://pdbe.org/7cv0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7cv0 RCSB], [http://www.ebi.ac.uk/pdbsum/7cv0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7cv0 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Jeong~~, K.H~~]]	+	__TOC__
-	[[Category: ~~Park, Y.W~~]]	+	</StructureSection>
-	[[Category: Lee~~, J.Y~~]]	+	[[Category: Large Structures]]
-	[[Category: Lee~~, D.W~~]]	+	[[Category: Jeong KH]]
-	[[Category: ~~Lee, M.Y~~]]	+	[[Category: Lee DW]]
		+	[[Category: Lee JY]]
		+	[[Category: Lee MY]]
		+	[[Category: Park YW]]

OCA at 05:19, 25 November 2020

OCA — Wed, 25 Nov 2020 05:19:50 GMT

←Older revision		Revision as of 05:19, 25 November 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7cv0 is ON HOLD	+	The entry 7cv0 is ON HOLD until Paper Publication

	Authors: Lee, J.Y., Lee, D.W., Park, Y.W., Lee, M.Y., Jeong, K.H.		Authors: Lee, J.Y., Lee, D.W., Park, Y.W., Lee, M.Y., Jeong, K.H.

OCA at 07:59, 18 November 2020

OCA — Wed, 18 Nov 2020 07:59:09 GMT

←Older revision		Revision as of 07:59, 18 November 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7cv0 is ON HOLD ~~until Paper Publication~~	+	The entry 7cv0 is ON HOLD

	Authors: Lee, J.Y., Lee, D.W., Park, Y.W., Lee, M.Y., Jeong, K.H.		Authors: Lee, J.Y., Lee, D.W., Park, Y.W., Lee, M.Y., Jeong, K.H.
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	Description: Crystal structure of B. halodurans NiaR in apo form		Description: Crystal structure of B. halodurans NiaR in apo form
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Lee, M.Y]]
	[[Category: Jeong, K.H]]		[[Category: Jeong, K.H]]
-	[[Category: Lee, D.W]]
-	[[Category: Lee, J.Y]]
	[[Category: Park, Y.W]]		[[Category: Park, Y.W]]
		+	[[Category: Lee, J.Y]]
		+	[[Category: Lee, D.W]]
		+	[[Category: Lee, M.Y]]

OCA at 06:49, 16 September 2020

OCA — Wed, 16 Sep 2020 06:49:58 GMT

←Older revision		Revision as of 06:49, 16 September 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7cv0 is ON HOLD	+	The entry 7cv0 is ON HOLD until Paper Publication

	Authors: Lee, J.Y., Lee, D.W., Park, Y.W., Lee, M.Y., Jeong, K.H.		Authors: Lee, J.Y., Lee, D.W., Park, Y.W., Lee, M.Y., Jeong, K.H.

-	Description: Crystal structure if B. halodurans NiaR in apo form	+	Description: Crystal structure of B. halodurans NiaR in apo form
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Lee, M.Y]]
	[[Category: Jeong, K.H]]		[[Category: Jeong, K.H]]
	[[Category: Lee, D.W]]		[[Category: Lee, D.W]]
-	[[Category: Park, Y.W]]
-	[[Category: Lee, M.Y]]
	[[Category: Lee, J.Y]]		[[Category: Lee, J.Y]]
		+	[[Category: Park, Y.W]]

OCA: Protected "7cv0" [edit=sysop:move=sysop]

OCA — Wed, 02 Sep 2020 05:14:44 GMT

Protected "7cv0" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:14, 2 September 2020

OCA: New page: '''Unreleased structure''' The entry 7cv0 is ON HOLD Authors: Lee, J.Y., Lee, D.W., Park, Y.W., Lee, M.Y., Jeong, K.H. Description: Crystal structure if B. halodurans NiaR in apo form ...

OCA — Wed, 02 Sep 2020 05:14:43 GMT

New page: '''Unreleased structure''' The entry 7cv0 is ON HOLD Authors: Lee, J.Y., Lee, D.W., Park, Y.W., Lee, M.Y., Jeong, K.H. Description: Crystal structure if B. halodurans NiaR in apo form ...

New page

'''Unreleased structure'''

The entry 7cv0 is ON HOLD

Authors: Lee, J.Y., Lee, D.W., Park, Y.W., Lee, M.Y., Jeong, K.H.

Description: Crystal structure if B. halodurans NiaR in apo form
[[Category: Unreleased Structures]]
[[Category: Jeong, K.H]]
[[Category: Lee, D.W]]
[[Category: Park, Y.W]]
[[Category: Lee, M.Y]]
[[Category: Lee, J.Y]]