7d1a - Revision history

OCA at 10:52, 27 March 2024

OCA — Wed, 27 Mar 2024 10:52:43 GMT

←Older revision		Revision as of 10:52, 27 March 2024
Line 1:		Line 1:

-	====	+	==cryo-EM structure of a group II intron RNP complexed with its reverse transcriptase==
-	<StructureSection load='7d1a' size='340' side='right'caption='[[7d1a]]' scene=''>	+	<StructureSection load='7d1a' size='340' side='right'caption='[[7d1a]], [[Resolution\|resolution]] 3.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7d1a]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_cremoris Lactococcus cremoris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7D1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7D1A FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7d1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7d1a OCA], [~~http~~://pdbe.org/7d1a PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7d1a RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7d1a PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7d1a ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.8Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7d1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7d1a OCA], [https://pdbe.org/7d1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7d1a RCSB], [https://www.ebi.ac.uk/pdbsum/7d1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7d1a ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/LTRA_LACLC LTRA_LACLC] Multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA. It has three activities: reverse transcriptase (RT) for intron duplication, maturase to promote splicing, and DNA endonuclease for site-specific cleavage of recipient alleles. The intron-encoded protein promotes splicing by facilitating the formation of the catalytically active structure of the intron RNA. After splicing, the protein remains bound to the excised intron lariat RNA, forming ribonucleoprotein particles, and cleaving the antisense strand of the recipient DNA in the 3' exon. After DNA cleavage, retrohoming occurs by a target DNA-primed reverse transcription of the intron RNA that had reverse spliced into the sense strand of the recipient DNA. It also contributes to the recognition of the DNA target site and acts as a repressor of its own translation.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Lactococcus cremoris]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Belfort M]]
		+	[[Category: Dong XL]]
		+	[[Category: Hu CX]]
		+	[[Category: Liu N]]
		+	[[Category: Wang HW]]
		+	[[Category: Wang J]]
		+	[[Category: Wang JW]]
		+	[[Category: Zeng JW]]

OCA at 08:17, 21 October 2020

OCA — Wed, 21 Oct 2020 08:17:51 GMT

←Older revision		Revision as of 08:17, 21 October 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7d1a ~~is ON HOLD~~	+	====
-		+	<StructureSection load='7d1a' size='340' side='right'caption='[[7d1a]]' scene=''>
-	~~Authors~~: ~~Liu, N~~.~~, Dong, X~~.L.~~, Hu, C~~.X.~~, Zeng, J~~.W.~~, Wang, J~~.W., ~~Wang, J~~.~~, Wang, H~~.W.~~, Belfort, M.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description: cryo~~-~~EM structure of a group II intron RNP complexed with its reverse transcriptase~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7d1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7d1a OCA], [http://pdbe.org/7d1a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7d1a RCSB], [http://www.ebi.ac.uk/pdbsum/7d1a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7d1a ProSAT]</span></td></tr>
-	~~[[Category: Unreleased Structures~~]]	+	</table>
-	[~~[Category~~: ~~Hu, C~~.X]]	+	__TOC__
-	~~[[Category: Liu~~, ~~N]]~~	+	</StructureSection>
-	[~~[Category~~: ~~Wang, H~~.W]]	+	[[Category: Large Structures]]
-	[~~[Category~~: ~~Zeng, J~~.W]]	+	[[Category: Z-disk]]
-	~~[[Category: Belfort~~, ~~M]]~~	+
-	[~~[Category~~: ~~Wang, J]~~]	+
-	[[Category: ~~Wang, J.W~~]]	+
-	[[Category: ~~Dong, X.L~~]]	+

OCA: Protected "7d1a" [edit=sysop:move=sysop]

OCA — Wed, 23 Sep 2020 08:55:51 GMT

Protected "7d1a" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:55, 23 September 2020

OCA: New page: '''Unreleased structure''' The entry 7d1a is ON HOLD Authors: Liu, N., Dong, X.L., Hu, C.X., Zeng, J.W., Wang, J.W., Wang, J., Wang, H.W., Belfort, M. Description: cryo-EM structure of...

OCA — Wed, 23 Sep 2020 08:55:50 GMT

New page: '''Unreleased structure''' The entry 7d1a is ON HOLD Authors: Liu, N., Dong, X.L., Hu, C.X., Zeng, J.W., Wang, J.W., Wang, J., Wang, H.W., Belfort, M. Description: cryo-EM structure of...

New page

'''Unreleased structure'''

The entry 7d1a is ON HOLD

Authors: Liu, N., Dong, X.L., Hu, C.X., Zeng, J.W., Wang, J.W., Wang, J., Wang, H.W., Belfort, M.

Description: cryo-EM structure of a group II intron RNP complexed with its reverse transcriptase
[[Category: Unreleased Structures]]
[[Category: Hu, C.X]]
[[Category: Liu, N]]
[[Category: Wang, H.W]]
[[Category: Zeng, J.W]]
[[Category: Belfort, M]]
[[Category: Wang, J]]
[[Category: Wang, J.W]]
[[Category: Dong, X.L]]