OCA at 17:01, 29 November 2023

OCA — Wed, 29 Nov 2023 17:01:38 GMT

←Older revision		Revision as of 17:01, 29 November 2023
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	==Structure and mutation analysis of the hexameric P4 from Pseudomonas aeruginosa phage phiYY==		==Structure and mutation analysis of the hexameric P4 from Pseudomonas aeruginosa phage phiYY==
-	<StructureSection load='7esq' size='340' side='right'caption='[[7esq]]' scene=''>	+	<StructureSection load='7esq' size='340' side='right'caption='[[7esq]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ESQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ESQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7esq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_phage_phiYY Pseudomonas phage phiYY]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ESQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ESQ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7esq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7esq OCA], [https://pdbe.org/7esq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7esq RCSB], [https://www.ebi.ac.uk/pdbsum/7esq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7esq ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7esq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7esq OCA], [https://pdbe.org/7esq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7esq RCSB], [https://www.ebi.ac.uk/pdbsum/7esq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7esq ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A1U9AK63_9VIRU A0A1U9AK63_9VIRU]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	phiYY is a foremost member of Cystoviridae isolated from Pseudomonas aeruginosa. Its P4 protein with NTPase activity is a molecular motor for their genome packing during viral particle assembly. Previously studies on the P4 from four Pseudomonas phages phi6, phi8, phi12 and phi13 reveal that despite of belonging to the same protein family, they are unique in sequence, structure and biochemical properties. To better understand the structure and function of phiYY P4, four crystal structures of phiYY P4 in apo-form or combined with different ligands were solved at the resolution between 1.85 A and 2.43 A, which showed drastic conformation change of the H1 motif in ligand-bound forms compared with in apo-form, a four residue-mutation at the ligand binding pocket abolished its ATPase activity. Furthermore, the truncation mutation of the 50 residues at the C-terminal did not impair the hexamerization and ATP hydrolysis.
		+
		+	Structure and mutation analysis of the hexameric P4 from Pseudomonas aeruginosa phage phiYY.,Zhang C, Li Y, Samad A, Zheng P, Ji Z, Chen F, Zhang H, Jin T Int J Biol Macromol. 2022 Jan 1;194:42-49. doi: 10.1016/j.ijbiomac.2021.11.129., Epub 2021 Nov 29. PMID:34856215<ref>PMID:34856215</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7esq" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Pseudomonas phage phiYY]]
	[[Category: Jin TC]]		[[Category: Jin TC]]
	[[Category: Zhang CY]]		[[Category: Zhang CY]]

OCA at 11:16, 23 March 2022

OCA — Wed, 23 Mar 2022 11:16:22 GMT

←Older revision		Revision as of 11:16, 23 March 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7esq ~~is ON HOLD until Paper Publication~~	+	==Structure and mutation analysis of the hexameric P4 from Pseudomonas aeruginosa phage phiYY==
-		+	<StructureSection load='7esq' size='340' side='right'caption='[[7esq]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ESQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ESQ FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7esq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7esq OCA], [https://pdbe.org/7esq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7esq RCSB], [https://www.ebi.ac.uk/pdbsum/7esq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7esq ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Jin TC]]
		+	[[Category: Zhang CY]]

OCA at 07:33, 29 September 2021

OCA — Wed, 29 Sep 2021 07:33:02 GMT

←Older revision		Revision as of 07:33, 29 September 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7esq is ON HOLD	+	The entry 7esq is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7esq" [edit=sysop:move=sysop]

OCA — Wed, 19 May 2021 08:45:41 GMT

Protected "7esq" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:45, 19 May 2021

OCA: New page: '''Unreleased structure''' The entry 7esq is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 19 May 2021 08:45:39 GMT

New page: '''Unreleased structure''' The entry 7esq is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7esq is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

7esq - Revision history

OCA at 17:01, 29 November 2023

OCA at 11:16, 23 March 2022

OCA at 07:33, 29 September 2021

OCA: Protected "7esq" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7esq is ON HOLD Authors: Description: Category: Unreleased Structures