7exy - Revision history

OCA at 11:13, 14 June 2023

OCA — Wed, 14 Jun 2023 11:13:10 GMT

←Older revision		Revision as of 11:13, 14 June 2023
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	==T-hairpin structure found in the RNA element involved in the piRNA biogenesis==		==T-hairpin structure found in the RNA element involved in the piRNA biogenesis==
-	<StructureSection load='7exy' size='340' side='right'caption='[[7exy~~]], [[NMR_Ensembles_of_Models \| 11 NMR models~~]]' scene=''>	+	<StructureSection load='7exy' size='340' side='right'caption='[[7exy]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7exy]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EXY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7exy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EXY FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7exy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7exy OCA], [https://pdbe.org/7exy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7exy RCSB], [https://www.ebi.ac.uk/pdbsum/7exy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7exy ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7exy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7exy OCA], [https://pdbe.org/7exy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7exy RCSB], [https://www.ebi.ac.uk/pdbsum/7exy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7exy ProSAT]</span></td></tr>
	</table>		</table>
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Drosophila melanogaster]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kawai, G]]	+	[[Category: Kawai G]]
-	[[Category: Takase, N]]	+	[[Category: Takase N]]
-	~~[[Category: Cis element]]~~	+
-	~~[[Category: Pirna]]~~	+
-	~~[[Category: Rna~~]]	+

OCA at 11:12, 30 March 2022

OCA — Wed, 30 Mar 2022 11:12:05 GMT

←Older revision		Revision as of 11:12, 30 March 2022
Line 1:		Line 1:

	==T-hairpin structure found in the RNA element involved in the piRNA biogenesis==		==T-hairpin structure found in the RNA element involved in the piRNA biogenesis==
-	<StructureSection load='7exy' size='340' side='right'caption='[[7exy]]' scene=''>	+	<StructureSection load='7exy' size='340' side='right'caption='[[7exy]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EXY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7exy]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EXY FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7exy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7exy OCA], [https://pdbe.org/7exy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7exy RCSB], [https://www.ebi.ac.uk/pdbsum/7exy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7exy ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7exy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7exy OCA], [https://pdbe.org/7exy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7exy RCSB], [https://www.ebi.ac.uk/pdbsum/7exy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7exy ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	PIWI-interacting RNAs (piRNAs) repress transposons to protect the germline genome from DNA damage caused by transposon transposition. In Drosophila, the Traffic jam (Tj) mRNA is consumed to produce piRNA in its 3' UTR. A cis element located within the 3'-UTR, Tj-cis, is necessary for piRNA biogenesis. In this study, we analyzed the structure of the Tj-cis RNA, a 100 nt RNA corresponding to the Tj-cis element, by the SHAPE and NMR analyses and found that a stable hairpin structure formed in the 5' half of the Tj-cis RNA. The tertiary structure of the 16 nt stable hairpin was analyzed by NMR, and a novel stem-loop structure, the T-hairpin, was found. In the T-hairpin, four uridine residues are exposed to the solvent, suggesting that this stem loop is the target of Yb protein, a Tudor domain-containing piRNA biogenesis factor. The piRNA biogenesis assay showed that both the T-hairpin and the 3' half are required for the function of the Tj-cis element, suggesting that both the T-hairpin and the 3' half are recognized by Yb protein.
		+
		+	T-hairpin structure found in the RNA element involved in piRNA biogenesis.,Takase N, Otsu M, Hirakata S, Ishizu H, Siomi MC, Kawai G RNA. 2022 Jan 5. pii: rna.078967.121. doi: 10.1261/rna.078967.121. PMID:34987083<ref>PMID:34987083</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7exy" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kawai G]]	+	[[Category: Kawai, G]]
-	[[Category: Takase N]]	+	[[Category: Takase, N]]
		+	[[Category: Cis element]]
		+	[[Category: Pirna]]
		+	[[Category: Rna]]

OCA at 06:16, 2 March 2022

OCA — Wed, 02 Mar 2022 06:16:46 GMT

←Older revision		Revision as of 06:16, 2 March 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 7exy is ON HOLD until May 29 2023~~	+	==T-hairpin structure found in the RNA element involved in the piRNA biogenesis==
-		+	<StructureSection load='7exy' size='340' side='right'caption='[[7exy]]' scene=''>
-	~~Authors: Takase, N., Kawai, G.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EXY FirstGlance]. <br>
-	~~Description:~~ T-hairpin structure found in the RNA element involved in the piRNA biogenesis	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7exy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7exy OCA], [https://pdbe.org/7exy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7exy RCSB], [https://www.ebi.ac.uk/pdbsum/7exy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7exy ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Kawai, G]]	+	__TOC__
-	[[Category: Takase, N]]	+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Kawai G]]
		+	[[Category: Takase N]]

OCA: Protected "7exy" [edit=sysop:move=sysop]

OCA — Wed, 09 Jun 2021 10:58:24 GMT

Protected "7exy" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:58, 9 June 2021

OCA: New page: '''Unreleased structure''' The entry 7exy is ON HOLD until May 29 2023 Authors: Takase, N., Kawai, G. Description: T-hairpin structure found in the RNA element involved in the piRNA bi...

OCA — Wed, 09 Jun 2021 10:58:23 GMT

New page: '''Unreleased structure''' The entry 7exy is ON HOLD until May 29 2023 Authors: Takase, N., Kawai, G. Description: T-hairpin structure found in the RNA element involved in the piRNA bi...

New page

'''Unreleased structure'''

The entry 7exy is ON HOLD until May 29 2023

Authors: Takase, N., Kawai, G.

Description: T-hairpin structure found in the RNA element involved in the piRNA biogenesis
[[Category: Unreleased Structures]]
[[Category: Kawai, G]]
[[Category: Takase, N]]