7fqt - Revision history

OCA at 10:30, 22 May 2024

OCA — Wed, 22 May 2024 10:30:26 GMT

←Older revision		Revision as of 10:30, 22 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7fqt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FQT FirstGlance]. <br>		<table><tr><td colspan='2'>[[7fqt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FQT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JJY:3,4,6,7-tetrahydroacridine-1,8(2H,5H)-dione'>JJY</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.54Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JJY:3,4,6,7-tetrahydroacridine-1,8(2H,5H)-dione'>JJY</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fqt OCA], [https://pdbe.org/7fqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fqt RCSB], [https://www.ebi.ac.uk/pdbsum/7fqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fqt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fqt OCA], [https://pdbe.org/7fqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fqt RCSB], [https://www.ebi.ac.uk/pdbsum/7fqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fqt ProSAT]</span></td></tr>
	</table>		</table>

OCA at 09:56, 24 November 2022

OCA — Thu, 24 Nov 2022 09:56:13 GMT

←Older revision		Revision as of 09:56, 24 November 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7fqt ~~is ON HOLD~~	+	==PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with FMOMB000293a==
-		+	<StructureSection load='7fqt' size='340' side='right'caption='[[7fqt]], [[Resolution\|resolution]] 2.54Å' scene=''>
-	~~Authors~~: ~~Mehlman, T~~.~~, Biel, J~~.~~, Azeem, S~~.M.~~, Nelson, E~~.R., ~~Hossain~~, S., ~~Dunnett~~, ~~L.E.~~, ~~Paterson~~, N.G., ~~Douangamath, A~~.~~, Talon, R~~., ~~Axford, D~~., ~~Orins, H~~., ~~von Delft, F~~., ~~Keedy, D~~.A.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7fqt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FQT FirstGlance]. <br>
-	~~Description~~: ~~PanDDA analysis group deposition~~ -~~-Crystal structure~~ of ~~PTP1B~~ in ~~complex with FMOMB000293a~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JJY:3,4,6,7-tetrahydroacridine-1,8(2H,5H)-dione'>JJY</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fqt OCA], [https://pdbe.org/7fqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fqt RCSB], [https://www.ebi.ac.uk/pdbsum/7fqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fqt ProSAT]</span></td></tr>
-	[[Category: ~~Mehlman, T~~]]	+	</table>
-	[[Category: ~~Biel, J~~]]	+	== Function ==
-	[[Category: ~~Nelson, E.R~~]]	+	[https://www.uniprot.org/uniprot/PTN1_HUMAN PTN1_HUMAN] Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion.<ref>PMID:21135139</ref> <ref>PMID:22169477</ref>
-	[[Category: ~~Azeem, S.M~~]]	+	== References ==
-	[[Category: ~~Paterson, N.G~~]]	+	<references/>
-	[[Category: Dunnett~~, L.E~~]]	+	__TOC__
-	[[Category: ~~Talon, R~~]]	+	</StructureSection>
-	[[Category: Keedy~~, D.A~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Douangamath, A~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Hossain, S~~]]	+	[[Category: Axford D]]
-	[[Category: Orins, H]]	+	[[Category: Azeem SM]]
-	[[Category: ~~Von Delft, F~~]]	+	[[Category: Biel J]]
-	[[Category: ~~Axford, D~~]]	+	[[Category: Douangamath A]]
		+	[[Category: Dunnett LE]]
		+	[[Category: Hossain S]]
		+	[[Category: Keedy DA]]
		+	[[Category: Mehlman T]]
		+	[[Category: Nelson ER]]
		+	[[Category: Orins H]]
		+	[[Category: Paterson NG]]
		+	[[Category: Talon R]]
		+	[[Category: Von Delft F]]

OCA: Protected "7fqt" [edit=sysop:move=sysop]

OCA — Wed, 26 Oct 2022 03:39:40 GMT

Protected "7fqt" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:39, 26 October 2022

OCA: New page: '''Unreleased structure''' The entry 7fqt is ON HOLD Authors: Mehlman, T., Biel, J., Azeem, S.M., Nelson, E.R., Hossain, S., Dunnett, L.E., Paterson, N.G., Douangamath, A., Talon, R., A...

OCA — Wed, 26 Oct 2022 03:39:39 GMT

New page: '''Unreleased structure''' The entry 7fqt is ON HOLD Authors: Mehlman, T., Biel, J., Azeem, S.M., Nelson, E.R., Hossain, S., Dunnett, L.E., Paterson, N.G., Douangamath, A., Talon, R., A...

New page

'''Unreleased structure'''

The entry 7fqt is ON HOLD

Authors: Mehlman, T., Biel, J., Azeem, S.M., Nelson, E.R., Hossain, S., Dunnett, L.E., Paterson, N.G., Douangamath, A., Talon, R., Axford, D., Orins, H., von Delft, F., Keedy, D.A.

Description: PanDDA analysis group deposition --Crystal structure of PTP1B in complex with FMOMB000293a
[[Category: Unreleased Structures]]
[[Category: Mehlman, T]]
[[Category: Biel, J]]
[[Category: Nelson, E.R]]
[[Category: Azeem, S.M]]
[[Category: Paterson, N.G]]
[[Category: Dunnett, L.E]]
[[Category: Talon, R]]
[[Category: Keedy, D.A]]
[[Category: Douangamath, A]]
[[Category: Hossain, S]]
[[Category: Orins, H]]
[[Category: Von Delft, F]]
[[Category: Axford, D]]