7fsq - Revision history

OCA at 10:32, 22 May 2024

OCA — Wed, 22 May 2024 10:32:44 GMT

←Older revision		Revision as of 10:32, 22 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7fsq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FSQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[7fsq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FSQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VVP:4-methoxy-1H-indole'>VVP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.07Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VVP:4-methoxy-1H-indole'>VVP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fsq OCA], [https://pdbe.org/7fsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fsq RCSB], [https://www.ebi.ac.uk/pdbsum/7fsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fsq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fsq OCA], [https://pdbe.org/7fsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fsq RCSB], [https://www.ebi.ac.uk/pdbsum/7fsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fsq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/SDCB1_HUMAN SDCB1_HUMAN] Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.<ref>PMID:10230395</ref> <ref>PMID:11179419</ref> <ref>PMID:11498591</ref>		[https://www.uniprot.org/uniprot/SDCB1_HUMAN SDCB1_HUMAN] Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.<ref>PMID:10230395</ref> <ref>PMID:11179419</ref> <ref>PMID:11498591</ref>
		+
		+	==See Also==
		+	*[[3D structures of syntenin\|3D structures of syntenin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:18, 15 February 2023

OCA — Wed, 15 Feb 2023 10:18:12 GMT

←Older revision		Revision as of 10:18, 15 February 2023
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-	'''Unreleased structure'''

-	The ~~entry~~ 7fsq ~~is ON HOLD~~	+	==SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1429867185==
-		+	<StructureSection load='7fsq' size='340' side='right'caption='[[7fsq]], [[Resolution\|resolution]] 2.07Å' scene=''>
-	~~Authors~~: ~~Bradshaw, W~~.J., ~~Katis~~, V.L., ~~Bountra~~, C., ~~von Delft~~, F., ~~Brennan, P~~.E.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7fsq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FSQ FirstGlance]. <br>
-	~~Description~~: ~~SDCBP PanDDA analysis group deposition -~~-~~The PDZ domans~~ of ~~SDCBP~~ in ~~complex with Z1429867185~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VVP:4-methoxy-1H-indole'>VVP</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fsq OCA], [https://pdbe.org/7fsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fsq RCSB], [https://www.ebi.ac.uk/pdbsum/7fsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fsq ProSAT]</span></td></tr>
-	[[Category: ~~Katis, V.L~~]]	+	</table>
-	[[Category: ~~Von Delft, F~~]]	+	== Function ==
-	[[Category: ~~Bountra, C~~]]	+	[https://www.uniprot.org/uniprot/SDCB1_HUMAN SDCB1_HUMAN] Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.<ref>PMID:10230395</ref> <ref>PMID:11179419</ref> <ref>PMID:11498591</ref>
-	[[Category: Brennan~~, P.E~~]]	+	== References ==
-	[[Category: ~~Bradshaw, W.J~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Bountra C]]
		+	[[Category: Bradshaw WJ]]
		+	[[Category: Brennan PE]]
		+	[[Category: Katis VL]]
		+	[[Category: Von Delft F]]

OCA: Protected "7fsq" [edit=sysop:move=sysop]

OCA — Wed, 01 Feb 2023 08:58:37 GMT

Protected "7fsq" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:58, 1 February 2023

OCA: New page: '''Unreleased structure''' The entry 7fsq is ON HOLD Authors: Bradshaw, W.J., Katis, V.L., Bountra, C., von Delft, F., Brennan, P.E. Description: SDCBP PanDDA analysis group deposition...

OCA — Wed, 01 Feb 2023 08:58:36 GMT

New page: '''Unreleased structure''' The entry 7fsq is ON HOLD Authors: Bradshaw, W.J., Katis, V.L., Bountra, C., von Delft, F., Brennan, P.E. Description: SDCBP PanDDA analysis group deposition...

New page

'''Unreleased structure'''

The entry 7fsq is ON HOLD

Authors: Bradshaw, W.J., Katis, V.L., Bountra, C., von Delft, F., Brennan, P.E.

Description: SDCBP PanDDA analysis group deposition --The PDZ domans of SDCBP in complex with Z1429867185
[[Category: Unreleased Structures]]
[[Category: Katis, V.L]]
[[Category: Von Delft, F]]
[[Category: Bountra, C]]
[[Category: Brennan, P.E]]
[[Category: Bradshaw, W.J]]