OCA at 21:13, 28 June 2023

OCA — Wed, 28 Jun 2023 21:13:09 GMT

←Older revision		Revision as of 21:13, 28 June 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 7fvt is ON HOLD until 2025-04-18~~	+	==Crystal Structure of S. aureus gyrase in complex with 6-[5-[2-[(4-chloro-2,3-dihydro-1H-inden-2-yl)methylamino]ethyl]-2-oxo-1,3-oxazolidin-3-yl]-4H-pyrido[3,2-b][1,4]oxazin-3-one==
-		+	<StructureSection load='7fvt' size='340' side='right'caption='[[7fvt]], [[Resolution\|resolution]] 2.08Å' scene=''>
-	~~Authors: Xu, B., Benz, J., Cumming, J.G., Rudolph, M.G.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7fvt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FVT FirstGlance]. <br>
-	~~Description:~~ Crystal Structure of S. aureus gyrase in complex with 6-[5-[2-[(4-chloro-2,3-dihydro-1H-inden-2-yl)methylamino]ethyl]-2-oxo-1,3-oxazolidin-3-yl]-4H-pyrido[3,2-b][1,4]oxazin-3-one	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.081Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6I0:6-{(5R)-5-[2-({[(2R)-4-chloro-2,3-dihydro-1H-inden-2-yl]methyl}amino)ethyl]-2-oxo-1,3-oxazolidin-3-yl}-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one'>6I0</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	[[Category: ~~Benz, J~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fvt OCA], [https://pdbe.org/7fvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fvt RCSB], [https://www.ebi.ac.uk/pdbsum/7fvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fvt ProSAT]</span></td></tr>
-	[[Category: ~~Xu, B~~]]	+	</table>
-	[[Category: ~~Cumming,~~ J.G]]	+	== Function ==
-	[[Category: Rudolph~~, M.G~~]]	+	[https://www.uniprot.org/uniprot/GYRA_STAAN GYRA_STAAN] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.[HAMAP-Rule:MF_01897][https://www.uniprot.org/uniprot/GYRB_STAAN GYRB_STAAN] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity).
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Staphylococcus aureus subsp. aureus N315]]
		+	[[Category: Synthetic construct]]
		+	[[Category: Benz J]]
		+	[[Category: Cumming JG]]
		+	[[Category: Rudolph MG]]
		+	[[Category: Xu B]]

OCA at 05:02, 3 May 2023

OCA — Wed, 03 May 2023 05:02:55 GMT

←Older revision		Revision as of 05:02, 3 May 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7fvt is ON HOLD	+	The entry 7fvt is ON HOLD until 2025-04-18

	Authors: Xu, B., Benz, J., Cumming, J.G., Rudolph, M.G.		Authors: Xu, B., Benz, J., Cumming, J.G., Rudolph, M.G.

OCA: Protected "7fvt" [edit=sysop:move=sysop]

OCA — Wed, 26 Apr 2023 14:43:16 GMT

Protected "7fvt" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:43, 26 April 2023

OCA: New page: '''Unreleased structure''' The entry 7fvt is ON HOLD Authors: Xu, B., Benz, J., Cumming, J.G., Rudolph, M.G. Description: Crystal Structure of S. aureus gyrase in complex with 6-[5-[2-...

OCA — Wed, 26 Apr 2023 14:43:15 GMT

New page: '''Unreleased structure''' The entry 7fvt is ON HOLD Authors: Xu, B., Benz, J., Cumming, J.G., Rudolph, M.G. Description: Crystal Structure of S. aureus gyrase in complex with 6-[5-[2-...

New page

'''Unreleased structure'''

The entry 7fvt is ON HOLD

Authors: Xu, B., Benz, J., Cumming, J.G., Rudolph, M.G.

Description: Crystal Structure of S. aureus gyrase in complex with 6-[5-[2-[(4-chloro-2,3-dihydro-1H-inden-2-yl)methylamino]ethyl]-2-oxo-1,3-oxazolidin-3-yl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
[[Category: Unreleased Structures]]
[[Category: Benz, J]]
[[Category: Xu, B]]
[[Category: Cumming, J.G]]
[[Category: Rudolph, M.G]]

7fvt - Revision history

OCA at 21:13, 28 June 2023

OCA at 05:02, 3 May 2023

OCA: Protected "7fvt" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7fvt is ON HOLD Authors: Xu, B., Benz, J., Cumming, J.G., Rudolph, M.G. Description: Crystal Structure of S. aureus gyrase in complex with 6-[5-[2-...