OCA at 11:23, 24 January 2024

OCA — Wed, 24 Jan 2024 11:23:15 GMT

←Older revision		Revision as of 11:23, 24 January 2024
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7gso is ~~ON HOLD~~	+	==PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOMB000029a==
-		+	<StructureSection load='7gso' size='340' side='right'caption='[[7gso]], [[Resolution\|resolution]] 1.72Å' scene=''>
-	~~Authors~~: ~~Mehlman~~, T., ~~Ginn~~, H.M., ~~Keedy~~, D.A.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7gso]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7GSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7GSO FirstGlance]. <br>
-	~~Description~~: ~~PanDDA Analysis group deposition~~ -~~-Crystal structure~~ of ~~PTP1B~~ in ~~complex with FMOMB000029a~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.72Å</td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1ABA:[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]methanol'>A1ABA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	[[Category: ~~Mehlman, T~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7gso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7gso OCA], [https://pdbe.org/7gso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7gso RCSB], [https://www.ebi.ac.uk/pdbsum/7gso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7gso ProSAT]</span></td></tr>
-	[[Category: Ginn~~, H.M~~]]	+	</table>
-	[[Category: Keedy~~, D.A~~]]	+	== Function ==
		+	[https://www.uniprot.org/uniprot/PTN1_HUMAN PTN1_HUMAN] Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion.<ref>PMID:21135139</ref> <ref>PMID:22169477</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Ginn HM]]
		+	[[Category: Keedy DA]]
		+	[[Category: Mehlman T]]

OCA: Protected "7gso" [edit=sysop:move=sysop]

OCA — Wed, 10 Jan 2024 09:10:41 GMT

Protected "7gso" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:10, 10 January 2024

OCA: New page: '''Unreleased structure''' The entry 7gso is ON HOLD Authors: Mehlman, T., Ginn, H.M., Keedy, D.A. Description: PanDDA Analysis group deposition --Crystal structure of PTP1B in complex...

OCA — Wed, 10 Jan 2024 09:10:40 GMT

New page: '''Unreleased structure''' The entry 7gso is ON HOLD Authors: Mehlman, T., Ginn, H.M., Keedy, D.A. Description: PanDDA Analysis group deposition --Crystal structure of PTP1B in complex...

New page

'''Unreleased structure'''

The entry 7gso is ON HOLD

Authors: Mehlman, T., Ginn, H.M., Keedy, D.A.

Description: PanDDA Analysis group deposition --Crystal structure of PTP1B in complex with FMOMB000029a
[[Category: Unreleased Structures]]
[[Category: Mehlman, T]]
[[Category: Ginn, H.M]]
[[Category: Keedy, D.A]]

7gso - Revision history

OCA at 11:23, 24 January 2024

OCA: Protected "7gso" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7gso is ON HOLD Authors: Mehlman, T., Ginn, H.M., Keedy, D.A. Description: PanDDA Analysis group deposition --Crystal structure of PTP1B in complex...