7jmu - Revision history

OCA at 15:06, 18 October 2023

OCA — Wed, 18 Oct 2023 15:06:55 GMT

←Older revision		Revision as of 15:06, 18 October 2023
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	<StructureSection load='7jmu' size='340' side='right'caption='[[7jmu]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='7jmu' size='340' side='right'caption='[[7jmu]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7jmu]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JMU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=7JMU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7jmu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JMU FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.2Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7jmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jmu OCA], [~~http~~://pdbe.org/7jmu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7jmu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7jmu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7jmu ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jmu OCA], [https://pdbe.org/7jmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jmu RCSB], [https://www.ebi.ac.uk/pdbsum/7jmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jmu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>	+	[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 7jmu" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 7jmu" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 28:
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Lysozyme]]~~	+	[[Category: Darmanin C]]
-	[[Category: Darmanin, C]]	+	[[Category: Drummond C]]
-	[[Category: Drummond, C]]	+	[[Category: Greaves T]]
-	[[Category: Greaves, T]]	+	[[Category: Han Q]]
-	[[Category: Han, Q]]	+	[[Category: Smith K]]
-	[[Category: Smith, K]]	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Ionic liquid]]~~	+
-	~~[[Category: Nitrate~~]]	+

OCA at 06:05, 20 January 2021

OCA — Wed, 20 Jan 2021 06:05:32 GMT

←Older revision		Revision as of 06:05, 20 January 2021
Line 1:		Line 1:

	==Hen egg-white lysozyme with ionic liquid ethylammonium nitrate==		==Hen egg-white lysozyme with ionic liquid ethylammonium nitrate==
-	<StructureSection load='7jmu' size='340' side='right'caption='[[7jmu]]' scene=''>	+	<StructureSection load='7jmu' size='340' side='right'caption='[[7jmu]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JMU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7JMU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7jmu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JMU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7JMU FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7jmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jmu OCA], [http://pdbe.org/7jmu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7jmu RCSB], [http://www.ebi.ac.uk/pdbsum/7jmu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7jmu ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7jmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jmu OCA], [http://pdbe.org/7jmu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7jmu RCSB], [http://www.ebi.ac.uk/pdbsum/7jmu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7jmu ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Solvents that support protein functionality are important for biochemical applications, and new solvents are required. Here we employ FTIR and fluorescence spectroscopies, small angle X-ray scattering (SAXS) and X-ray crystallography to understand conformational changes of lysozyme with ionic liquids (ILs) added. Spectroscopic techniques identified that the secondary structure of lysozyme was maintained at the lower IL concentrations of 1 and 5 mol%, though the Tryptophan environment was significantly altered with nitrate-based ILs present. SAXS experiments indicated that the radius of gyration of lysozyme increased with 1 mol% IL present, and then decreased with increasing IL concentrations. The tertiary structure, particularly the loop regions, changed as a function of IL concentration, and this depended on the IL type. The crystallographic structure of lysozyme with the IL of ethylammonium nitrate present confirmed the loop region was extended, and identified three specific binding sites with nitrate ions, and that the positively charged areas were IL sensitive regions. This work provides a detailed understanding of lysozyme conformational changes in the presence of ILs. This approach can be extended to other functionally-important proteins.
		+
		+	Lysozyme conformational changes with ionic liquids: Spectroscopic, small angle x-ray scattering and crystallographic study.,Han Q, Smith KM, Darmanin C, Ryan TM, Drummond CJ, Greaves TL J Colloid Interface Sci. 2020 Oct 13. pii: S0021-9797(20)31347-3. doi:, 10.1016/j.jcis.2020.10.024. PMID:33109332<ref>PMID:33109332</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7jmu" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Darmanin C]]	+	[[Category: Lysozyme]]
-	[[Category: Drummond C]]	+	[[Category: Darmanin, C]]
-	[[Category: Greaves T]]	+	[[Category: Drummond, C]]
-	[[Category: Han Q]]	+	[[Category: Greaves, T]]
-	[[Category: Smith K]]	+	[[Category: Han, Q]]
		+	[[Category: Smith, K]]
		+	[[Category: Hydrolase]]
		+	[[Category: Ionic liquid]]
		+	[[Category: Nitrate]]

OCA at 08:03, 11 November 2020

OCA — Wed, 11 Nov 2020 08:03:15 GMT

←Older revision		Revision as of 08:03, 11 November 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 7jmu ~~is ON HOLD until Aug 02 2022~~	+	==Hen egg-white lysozyme with ionic liquid ethylammonium nitrate==
-		+	<StructureSection load='7jmu' size='340' side='right'caption='[[7jmu]]' scene=''>
-	~~Authors~~: ~~Han~~, Q., ~~Darmanin, C~~., ~~Smith, K~~., ~~Greaves, T~~., ~~Drummond, C~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JMU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7JMU FirstGlance]. <br>
-	~~Description: Hen egg-white lysozyme with ionic liquid ethylammonium nitrate~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7jmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jmu OCA], [http://pdbe.org/7jmu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7jmu RCSB], [http://www.ebi.ac.uk/pdbsum/7jmu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7jmu ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Darmanin, C]]	+	__TOC__
-	[[Category: ~~Han, Q~~]]	+	</StructureSection>
-	[[Category: ~~Smith, K~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Greaves, T~~]]	+	[[Category: Darmanin C]]
-	[[Category: ~~Drummond, C~~]]	+	[[Category: Drummond C]]
		+	[[Category: Greaves T]]
		+	[[Category: Han Q]]
		+	[[Category: Smith K]]

OCA: Protected "7jmu" [edit=sysop:move=sysop]

OCA — Wed, 12 Aug 2020 08:30:39 GMT

Protected "7jmu" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:30, 12 August 2020

OCA: New page: '''Unreleased structure''' The entry 7jmu is ON HOLD until Aug 02 2022 Authors: Han, Q., Darmanin, C., Smith, K., Greaves, T., Drummond, C. Description: Hen egg-white lysozyme with ion...

OCA — Wed, 12 Aug 2020 08:30:37 GMT

New page: '''Unreleased structure''' The entry 7jmu is ON HOLD until Aug 02 2022 Authors: Han, Q., Darmanin, C., Smith, K., Greaves, T., Drummond, C. Description: Hen egg-white lysozyme with ion...

New page

'''Unreleased structure'''

The entry 7jmu is ON HOLD until Aug 02 2022

Authors: Han, Q., Darmanin, C., Smith, K., Greaves, T., Drummond, C.

Description: Hen egg-white lysozyme with ionic liquid ethylammonium nitrate
[[Category: Unreleased Structures]]
[[Category: Darmanin, C]]
[[Category: Han, Q]]
[[Category: Smith, K]]
[[Category: Greaves, T]]
[[Category: Drummond, C]]