7kas - Revision history

OCA at 14:56, 6 March 2024

OCA — Wed, 06 Mar 2024 14:56:12 GMT

←Older revision		Revision as of 14:56, 6 March 2024
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-	====	+	==Cryo-EM structure of the Sec complex from S. cerevisiae, Sec63 FN3 mutant, class with Sec62==
-	<StructureSection load='7kas' size='340' side='right'caption='[[7kas]]' scene=''>	+	<StructureSection load='7kas' size='340' side='right'caption='[[7kas]], [[Resolution\|resolution]] 3.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7kas]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_BY4741 Saccharomyces cerevisiae BY4741]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KAS FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kas OCA], [https://pdbe.org/7kas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kas RCSB], [https://www.ebi.ac.uk/pdbsum/7kas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kas ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.9Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kas OCA], [https://pdbe.org/7kas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kas RCSB], [https://www.ebi.ac.uk/pdbsum/7kas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kas ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/SC61A_YEAST SC61A_YEAST] Part of the Sec61 complex, which is the major component of a channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). The functional states of the translocon complex include co- and post-translational ER import, cotranslational membrane protein integration and retrograde transport of misfolded proteins out of the ER. In the cotranslational pathway, ribosomes synthesizing presecretory proteins are targeted to the translocon by the cytosolic signal recognition particle (SRP) and its ER-localized receptor. The association of the Sec61 complex with the ribosome is mediated by the 28S rRNA of the large ribosomal subunit. SRP-independent post-translational translocation requires the association of additional factors, such as the Sec62/63 complex and KAR2. In an initial step, the signal sequence seems to bind simultaneously to SEC61 and SEC62. A cycle of assembly and disassembly of Sec62/63 complex from SEC61 may govern the activity of the translocon. SEC61 mediates the association with the ribosome.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Saccharomyces cerevisiae BY4741]]
		+	[[Category: Itskanov S]]
		+	[[Category: Park E]]

OCA at 06:47, 24 February 2021

OCA — Wed, 24 Feb 2021 06:47:20 GMT

←Older revision		Revision as of 06:47, 24 February 2021
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	<StructureSection load='7kas' size='340' side='right'caption='[[7kas]]' scene=''>		<StructureSection load='7kas' size='340' side='right'caption='[[7kas]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7kas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kas OCA], [~~http~~://pdbe.org/7kas PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7kas RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7kas PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7kas ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kas OCA], [https://pdbe.org/7kas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kas RCSB], [https://www.ebi.ac.uk/pdbsum/7kas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kas ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 08:56, 6 January 2021

OCA — Wed, 06 Jan 2021 08:56:57 GMT

←Older revision		Revision as of 08:56, 6 January 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7kas ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='7kas' size='340' side='right'caption='[[7kas]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7kas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kas OCA], [http://pdbe.org/7kas PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7kas RCSB], [http://www.ebi.ac.uk/pdbsum/7kas PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7kas ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 04:20, 14 October 2020

OCA — Wed, 14 Oct 2020 04:20:20 GMT

←Older revision		Revision as of 04:20, 14 October 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7kas is ON HOLD	+	The entry 7kas is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7kas" [edit=sysop:move=sysop]

OCA — Wed, 07 Oct 2020 04:52:06 GMT

Protected "7kas" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:52, 7 October 2020

OCA: New page: '''Unreleased structure''' The entry 7kas is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 07 Oct 2020 04:52:05 GMT

New page: '''Unreleased structure''' The entry 7kas is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7kas is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]