7khe - Revision history

OCA at 14:56, 6 March 2024

OCA — Wed, 06 Mar 2024 14:56:55 GMT

←Older revision		Revision as of 14:56, 6 March 2024
Line 1:		Line 1:

-	====	+	==Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex with DksA/ppGpp==
-	<StructureSection load='7khe' size='340' side='right'caption='[[7khe]]' scene=''>	+	<StructureSection load='7khe' size='340' side='right'caption='[[7khe]], [[Resolution\|resolution]] 3.58Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7khe]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6wrg 6wrg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KHE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KHE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7khe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7khe OCA], [https://pdbe.org/7khe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7khe RCSB], [https://www.ebi.ac.uk/pdbsum/7khe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7khe ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.58Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1N7:CHAPSO'>1N7</scene>, <scene name='pdbligand=G4P:GUANOSINE-5,3-TETRAPHOSPHATE'>G4P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7khe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7khe OCA], [https://pdbe.org/7khe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7khe RCSB], [https://www.ebi.ac.uk/pdbsum/7khe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7khe ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/DKSA_ECOLI DKSA_ECOLI] Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. Binding to RNAP disrupts interaction of RNAP with DNA, inhibits formation of initiation complexes, and amplifies effects of ppGpp and the initiating NTP on rRNA transcription. Inhibits transcript elongation, exonucleolytic RNA cleavage and pyrophosphorolysis, and increases intrinsic termination. Also involved, with RecN, in repair of DNA double-strand breaks.<ref>PMID:15294157</ref> <ref>PMID:15948952</ref> <ref>PMID:16885445</ref> <ref>PMID:22210857</ref> <ref>PMID:15294156</ref>
		+
		+	==See Also==
		+	*[[RNA polymerase 3D structures\|RNA polymerase 3D structures]]
		+	*[[Sigma factor 3D structures\|Sigma factor 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Murakami KS]]
		+	[[Category: Qayyum MZ]]
		+	[[Category: Shin Y]]

OCA at 11:18, 3 February 2021

OCA — Wed, 03 Feb 2021 11:18:00 GMT

←Older revision		Revision as of 11:18, 3 February 2021
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	<StructureSection load='7khe' size='340' side='right'caption='[[7khe]]' scene=''>		<StructureSection load='7khe' size='340' side='right'caption='[[7khe]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7khe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7khe OCA], [~~http~~://pdbe.org/7khe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7khe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7khe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7khe ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7khe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7khe OCA], [https://pdbe.org/7khe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7khe RCSB], [https://www.ebi.ac.uk/pdbsum/7khe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7khe ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 06:33, 9 December 2020

OCA — Wed, 09 Dec 2020 06:33:41 GMT

←Older revision

Revision as of 06:33, 9 December 2020

OCA: Protected "7khe" [edit=sysop:move=sysop]

OCA — Wed, 28 Oct 2020 19:12:13 GMT

Protected "7khe" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:12, 28 October 2020

OCA: New page: '''Unreleased structure''' The entry 7khe is ON HOLD Authors: Shin, Y., Qayyum, M.Z., Murakami, K.S. Description: Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex w...

OCA — Wed, 28 Oct 2020 19:12:12 GMT

New page: '''Unreleased structure''' The entry 7khe is ON HOLD Authors: Shin, Y., Qayyum, M.Z., Murakami, K.S. Description: Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex w...

New page

'''Unreleased structure'''

The entry 7khe is ON HOLD

Authors: Shin, Y., Qayyum, M.Z., Murakami, K.S.

Description: Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex with DksA/ppGpp
[[Category: Unreleased Structures]]
[[Category: Qayyum, M.Z]]
[[Category: Shin, Y]]
[[Category: Murakami, K.S]]