7klv - Revision history

OCA at 19:36, 29 May 2024

OCA — Wed, 29 May 2024 19:36:01 GMT

←Older revision		Revision as of 19:36, 29 May 2024
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-	====	+	==Full-length human mitochondrial Hsp90 (TRAP1) SpyCatcher/SpyTag-SdhB heterodimer in the presence of AMP-PNP==
-	<StructureSection load='7klv' size='340' side='right'caption='[[7klv]]' scene=''>	+	<StructureSection load='7klv' size='340' side='right'caption='[[7klv]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7klv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KLV FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7klv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7klv OCA], [https://pdbe.org/7klv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7klv RCSB], [https://www.ebi.ac.uk/pdbsum/7klv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7klv ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7klv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7klv OCA], [https://pdbe.org/7klv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7klv RCSB], [https://www.ebi.ac.uk/pdbsum/7klv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7klv ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/TRAP1_HUMAN TRAP1_HUMAN] Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.<ref>PMID:23525905</ref> <ref>PMID:23564345</ref> <ref>PMID:23747254</ref>
		+
		+	==See Also==
		+	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Synthetic construct]]
		+	[[Category: Agard DA]]
		+	[[Category: Liu YX]]

OCA at 14:30, 3 November 2021

OCA — Wed, 03 Nov 2021 14:30:32 GMT

←Older revision		Revision as of 14:30, 3 November 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7klv ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='7klv' size='340' side='right'caption='[[7klv]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7klv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7klv OCA], [https://pdbe.org/7klv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7klv RCSB], [https://www.ebi.ac.uk/pdbsum/7klv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7klv ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 05:12, 9 December 2020

OCA — Wed, 09 Dec 2020 05:12:55 GMT

←Older revision		Revision as of 05:12, 9 December 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7klv is ON HOLD	+	The entry 7klv is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7klv" [edit=sysop:move=sysop]

OCA — Wed, 11 Nov 2020 06:33:21 GMT

Protected "7klv" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:33, 11 November 2020

OCA: New page: '''Unreleased structure''' The entry 7klv is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 11 Nov 2020 06:33:19 GMT

New page: '''Unreleased structure''' The entry 7klv is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7klv is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]