7kua - Revision history

OCA at 09:19, 25 October 2023

OCA — Wed, 25 Oct 2023 09:19:27 GMT

←Older revision		Revision as of 09:19, 25 October 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7kua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KUA FirstGlance]. <br>		<table><tr><td colspan='2'>[[7kua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KUA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IAC:1H-INDOL-3-YLACETIC+ACID'>IAC</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.89Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IAC:1H-INDOL-3-YLACETIC+ACID'>IAC</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kua OCA], [https://pdbe.org/7kua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kua RCSB], [https://www.ebi.ac.uk/pdbsum/7kua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kua ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kua OCA], [https://pdbe.org/7kua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kua RCSB], [https://www.ebi.ac.uk/pdbsum/7kua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kua ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:21, 24 November 2022

OCA — Thu, 24 Nov 2022 10:21:30 GMT

←Older revision		Revision as of 10:21, 24 November 2022
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	==Crystal structure of the MarR family transcriptional regulator from Pseudomonas putida bound to Indole 3 acetic acid==		==Crystal structure of the MarR family transcriptional regulator from Pseudomonas putida bound to Indole 3 acetic acid==
-	<StructureSection load='7kua' size='340' side='right'caption='[[7kua]]' scene=''>	+	<StructureSection load='7kua' size='340' side='right'caption='[[7kua]], [[Resolution\|resolution]] 1.89Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7kua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KUA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kua OCA], [https://pdbe.org/7kua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kua RCSB], [https://www.ebi.ac.uk/pdbsum/7kua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kua ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IAC:1H-INDOL-3-YLACETIC+ACID'>IAC</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kua OCA], [https://pdbe.org/7kua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kua RCSB], [https://www.ebi.ac.uk/pdbsum/7kua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kua ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/IACR_PSEPU IACR_PSEPU] Probably acts as a repressor of iacA expression.<ref>PMID:23881445</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Chemical signalling in the plant microbiome can have drastic effects on microbial community structure, and on host growth and development. Previously, we demonstrated that the auxin metabolic signal interference performed by the bacterial genus Variovorax via an auxin degradation locus was essential for maintaining stereotypic root development in an ecologically relevant bacterial synthetic community. Here, we dissect the Variovorax auxin degradation locus to define the genes iadDE as necessary and sufficient for indole-3-acetic acid (IAA) degradation and signal interference. We determine the crystal structures and binding properties of the operon's MarR-family repressor with IAA and other auxins. Auxin degradation operons were identified across the bacterial tree of life and we define two distinct types on the basis of gene content and metabolic products: iac-like and iad-like. The structures of MarRs from representatives of each auxin degradation operon type establish that each has distinct IAA-binding pockets. Comparison of representative IAA-degrading strains from diverse bacterial genera colonizing Arabidopsis plants show that while all degrade IAA, only strains containing iad-like auxin-degrading operons interfere with auxin signalling in a complex synthetic community context. This suggests that iad-like operon-containing bacterial strains, including Variovorax species, play a key ecological role in modulating auxins in the plant microbiome.
		+
		+	Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome.,Conway JM, Walton WG, Salas-Gonzalez I, Law TF, Lindberg CA, Crook LE, Kosina SM, Fitzpatrick CR, Lietzan AD, Northen TR, Jones CD, Finkel OM, Redinbo MR, Dangl JL Nat Microbiol. 2022 Nov;7(11):1817-1833. doi: 10.1038/s41564-022-01244-3. Epub , 2022 Oct 20. PMID:36266335<ref>PMID:36266335</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7kua" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Pseudomonas putida]]
	[[Category: Dangl JL]]		[[Category: Dangl JL]]
	[[Category: Lietzan AD]]		[[Category: Lietzan AD]]
	[[Category: Redinbo MR]]		[[Category: Redinbo MR]]
	[[Category: Walton WG]]		[[Category: Walton WG]]

OCA at 06:19, 1 December 2021

OCA — Wed, 01 Dec 2021 06:19:44 GMT

←Older revision		Revision as of 06:19, 1 December 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7kua is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of the MarR family transcriptional regulator from Pseudomonas putida bound to Indole 3 acetic acid==
-		+	<StructureSection load='7kua' size='340' side='right'caption='[[7kua]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KUA FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kua OCA], [https://pdbe.org/7kua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kua RCSB], [https://www.ebi.ac.uk/pdbsum/7kua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kua ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Dangl JL]]
		+	[[Category: Lietzan AD]]
		+	[[Category: Redinbo MR]]
		+	[[Category: Walton WG]]

OCA at 05:45, 6 January 2021

OCA — Wed, 06 Jan 2021 05:45:52 GMT

←Older revision		Revision as of 05:45, 6 January 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7kua is ON HOLD	+	The entry 7kua is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7kua" [edit=sysop:move=sysop]

OCA — Wed, 02 Dec 2020 05:54:46 GMT

Protected "7kua" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:54, 2 December 2020

OCA: New page: '''Unreleased structure''' The entry 7kua is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 02 Dec 2020 05:54:45 GMT

New page: '''Unreleased structure''' The entry 7kua is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7kua is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]