7kym - Revision history

OCA at 09:19, 25 October 2023

OCA — Wed, 25 Oct 2023 09:19:37 GMT

←Older revision		Revision as of 09:19, 25 October 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7kym]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KYM FirstGlance]. <br>		<table><tr><td colspan='2'>[[7kym]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KYM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kym OCA], [https://pdbe.org/7kym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kym RCSB], [https://www.ebi.ac.uk/pdbsum/7kym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kym ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kym OCA], [https://pdbe.org/7kym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kym RCSB], [https://www.ebi.ac.uk/pdbsum/7kym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kym ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:21, 24 November 2022

OCA — Thu, 24 Nov 2022 10:21:32 GMT

←Older revision		Revision as of 10:21, 24 November 2022
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	==Crystal structure of the MarR family transcriptional regulator from Bradyrhizobium japonicum==		==Crystal structure of the MarR family transcriptional regulator from Bradyrhizobium japonicum==
-	<StructureSection load='7kym' size='340' side='right'caption='[[7kym]]' scene=''>	+	<StructureSection load='7kym' size='340' side='right'caption='[[7kym]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KYM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7kym]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KYM FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kym OCA], [https://pdbe.org/7kym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kym RCSB], [https://www.ebi.ac.uk/pdbsum/7kym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kym ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kym OCA], [https://pdbe.org/7kym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kym RCSB], [https://www.ebi.ac.uk/pdbsum/7kym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kym ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0A3XYM8_BRAJP A0A0A3XYM8_BRAJP]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Chemical signalling in the plant microbiome can have drastic effects on microbial community structure, and on host growth and development. Previously, we demonstrated that the auxin metabolic signal interference performed by the bacterial genus Variovorax via an auxin degradation locus was essential for maintaining stereotypic root development in an ecologically relevant bacterial synthetic community. Here, we dissect the Variovorax auxin degradation locus to define the genes iadDE as necessary and sufficient for indole-3-acetic acid (IAA) degradation and signal interference. We determine the crystal structures and binding properties of the operon's MarR-family repressor with IAA and other auxins. Auxin degradation operons were identified across the bacterial tree of life and we define two distinct types on the basis of gene content and metabolic products: iac-like and iad-like. The structures of MarRs from representatives of each auxin degradation operon type establish that each has distinct IAA-binding pockets. Comparison of representative IAA-degrading strains from diverse bacterial genera colonizing Arabidopsis plants show that while all degrade IAA, only strains containing iad-like auxin-degrading operons interfere with auxin signalling in a complex synthetic community context. This suggests that iad-like operon-containing bacterial strains, including Variovorax species, play a key ecological role in modulating auxins in the plant microbiome.
		+
		+	Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome.,Conway JM, Walton WG, Salas-Gonzalez I, Law TF, Lindberg CA, Crook LE, Kosina SM, Fitzpatrick CR, Lietzan AD, Northen TR, Jones CD, Finkel OM, Redinbo MR, Dangl JL Nat Microbiol. 2022 Nov;7(11):1817-1833. doi: 10.1038/s41564-022-01244-3. Epub , 2022 Oct 20. PMID:36266335<ref>PMID:36266335</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7kym" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bradyrhizobium japonicum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Dangl JL]]		[[Category: Dangl JL]]
	[[Category: Redinbo MR]]		[[Category: Redinbo MR]]
	[[Category: Walton WG]]		[[Category: Walton WG]]

OCA at 16:47, 15 December 2021

OCA — Wed, 15 Dec 2021 16:47:39 GMT

←Older revision		Revision as of 16:47, 15 December 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7kym is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of the MarR family transcriptional regulator from Bradyrhizobium japonicum==
-		+	<StructureSection load='7kym' size='340' side='right'caption='[[7kym]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KYM FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kym OCA], [https://pdbe.org/7kym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kym RCSB], [https://www.ebi.ac.uk/pdbsum/7kym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kym ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Dangl JL]]
		+	[[Category: Redinbo MR]]
		+	[[Category: Walton WG]]

OCA at 06:51, 20 January 2021

OCA — Wed, 20 Jan 2021 06:51:00 GMT

←Older revision		Revision as of 06:51, 20 January 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7kym is ON HOLD	+	The entry 7kym is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7kym" [edit=sysop:move=sysop]

OCA — Wed, 16 Dec 2020 11:15:54 GMT

Protected "7kym" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:15, 16 December 2020

OCA: New page: '''Unreleased structure''' The entry 7kym is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 16 Dec 2020 11:15:53 GMT

New page: '''Unreleased structure''' The entry 7kym is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7kym is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]