7kzf - Revision history

OCA at 14:58, 6 March 2024

OCA — Wed, 06 Mar 2024 14:58:19 GMT

←Older revision		Revision as of 14:58, 6 March 2024
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	==High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility==		==High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility==
-	<StructureSection load='7kzf' size='340' side='right'caption='[[7kzf]]' scene=''>	+	<StructureSection load='7kzf' size='340' side='right'caption='[[7kzf]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KZF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7kzf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_papillomavirus_type_16 Human papillomavirus type 16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KZF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kzf OCA], [https://pdbe.org/7kzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kzf RCSB], [https://www.ebi.ac.uk/pdbsum/7kzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kzf ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.1Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kzf OCA], [https://pdbe.org/7kzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kzf RCSB], [https://www.ebi.ac.uk/pdbsum/7kzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kzf ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/VL1_HPV16 VL1_HPV16] Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.[HAMAP-Rule:MF_04002]<ref>PMID:12610160</ref> <ref>PMID:26289843</ref> <ref>PMID:8553535</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human papillomavirus type 16]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Goetschius DJ]]		[[Category: Goetschius DJ]]
	[[Category: Hafenstein S]]		[[Category: Hafenstein S]]
	[[Category: Hartmann SR]]		[[Category: Hartmann SR]]

OCA at 06:41, 24 February 2021

OCA — Wed, 24 Feb 2021 06:41:00 GMT

←Older revision		Revision as of 06:41, 24 February 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7kzf is ~~ON HOLD~~	+	==High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility==
-		+	<StructureSection load='7kzf' size='340' side='right'caption='[[7kzf]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KZF FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kzf OCA], [https://pdbe.org/7kzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kzf RCSB], [https://www.ebi.ac.uk/pdbsum/7kzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kzf ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Goetschius DJ]]
		+	[[Category: Hafenstein S]]
		+	[[Category: Hartmann SR]]

OCA: Protected "7kzf" [edit=sysop:move=sysop]

OCA — Wed, 16 Dec 2020 11:17:43 GMT

Protected "7kzf" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:17, 16 December 2020

OCA: New page: '''Unreleased structure''' The entry 7kzf is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 16 Dec 2020 11:17:42 GMT

New page: '''Unreleased structure''' The entry 7kzf is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7kzf is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]