OCA at 15:36, 18 October 2023

OCA — Wed, 18 Oct 2023 15:36:32 GMT

←Older revision		Revision as of 15:36, 18 October 2023
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	==PEPCK steady-state structure with Mn and GTP==		==PEPCK steady-state structure with Mn and GTP==
-	<StructureSection load='7l36' size='340' side='right'caption='[[7l36]]' scene=''>	+	<StructureSection load='7l36' size='340' side='right'caption='[[7l36]], [[Resolution\|resolution]] 1.84Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L36 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7l36]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L36 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l36 OCA], [https://pdbe.org/7l36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l36 RCSB], [https://www.ebi.ac.uk/pdbsum/7l36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l36 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.84Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l36 OCA], [https://pdbe.org/7l36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l36 RCSB], [https://www.ebi.ac.uk/pdbsum/7l36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l36 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PCKGC_RAT PCKGC_RAT] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Time-resolved crystallography of biomolecules in action has advanced rapidly as methods for serial crystallography have improved, but the large number of crystals and the complex experimental infrastructure that are required remain serious obstacles to its widespread application. Here, millisecond mix-and-quench crystallography (MMQX) has been developed, which yields millisecond time-resolved data using far fewer crystals and routine remote synchrotron data collection. To demonstrate the capabilities of MMQX, the conversion of oxaloacetic acid to phosphoenolpyruvate by phosphoenolpyruvate carboxy-kinase (PEPCK) is observed with a time resolution of 40 ms. By lowering the entry barrier to time-resolved crystallography, MMQX should enable a broad expansion in structural studies of protein dynamics.
		+
		+	Millisecond mix-and-quench crystallography (MMQX) enables time-resolved studies of PEPCK with remote data collection.,Clinger JA, Moreau DW, McLeod MJ, Holyoak T, Thorne RE IUCrJ. 2021 Aug 4;8(Pt 5):784-792. doi: 10.1107/S2052252521007053. eCollection, 2021 Sep 1. PMID:34584739<ref>PMID:34584739</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7l36" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Phosphoenolpyruvate carboxykinase 3D structures\|Phosphoenolpyruvate carboxykinase 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Rattus norvegicus]]
	[[Category: Clinger JA]]		[[Category: Clinger JA]]
	[[Category: Holyoak T]]		[[Category: Holyoak T]]

OCA at 11:42, 13 October 2021

OCA — Wed, 13 Oct 2021 11:42:04 GMT

←Older revision		Revision as of 11:42, 13 October 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7l36 is ~~ON HOLD until Paper Publication~~	+	==PEPCK steady-state structure with Mn and GTP==
-		+	<StructureSection load='7l36' size='340' side='right'caption='[[7l36]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L36 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l36 OCA], [https://pdbe.org/7l36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l36 RCSB], [https://www.ebi.ac.uk/pdbsum/7l36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l36 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Clinger JA]]
		+	[[Category: Holyoak T]]
		+	[[Category: McLeod MJ]]
		+	[[Category: Moreau DW]]
		+	[[Category: Thorne RE]]

OCA at 06:43, 27 January 2021

OCA — Wed, 27 Jan 2021 06:43:55 GMT

←Older revision		Revision as of 06:43, 27 January 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7l36 is ON HOLD	+	The entry 7l36 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7l36" [edit=sysop:move=sysop]

OCA — Thu, 24 Dec 2020 08:13:59 GMT

Protected "7l36" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:13, 24 December 2020

OCA: New page: '''Unreleased structure''' The entry 7l36 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Thu, 24 Dec 2020 08:13:56 GMT

New page: '''Unreleased structure''' The entry 7l36 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7l36 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

7l36 - Revision history

OCA at 15:36, 18 October 2023

OCA at 11:42, 13 October 2021

OCA at 06:43, 27 January 2021

OCA: Protected "7l36" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7l36 is ON HOLD Authors: Description: Category: Unreleased Structures