7l84 - Revision history

OCA at 03:47, 8 September 2022

OCA — Thu, 08 Sep 2022 03:47:37 GMT

←Older revision		Revision as of 03:47, 8 September 2022
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7l84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L84 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7l84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L84 FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l84 OCA], [https://pdbe.org/7l84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l84 RCSB], [https://www.ebi.ac.uk/pdbsum/7l84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l84 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l84 OCA], [https://pdbe.org/7l84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l84 RCSB], [https://www.ebi.ac.uk/pdbsum/7l84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l84 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>	+	[[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Lysozyme]]~~	+	[[Category: Dalton KM]]
-	[[Category: Dalton~~, K M~~]]	+	[[Category: Greisman JB]]
-	[[Category: Greisman~~, J B~~]]	+	[[Category: Hekstra DR]]
-	[[Category: Hekstra~~, D R]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 06:32, 18 August 2022

OCA — Thu, 18 Aug 2022 06:32:21 GMT

←Older revision		Revision as of 06:32, 18 August 2022
Line 9:		Line 9:
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>		[[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Single-wavelength anomalous diffraction (SAD) is a routine method for overcoming the phase problem when solving macromolecular structures. This technique requires the accurate measurement of intensities to determine differences between Bijvoet pairs. Although SAD experiments are commonly conducted at cryogenic temperatures to mitigate the effects of radiation damage, such temperatures can alter the conformational ensemble of the protein and may impede the merging of data from multiple crystals due to non-uniform freezing. Here, a strategy is presented to obtain high-quality data from room-temperature, single-crystal experiments. To illustrate the strengths of this approach, native SAD phasing at 6.55 keV was used to solve four structures of three model systems at 295 K. The resulting data sets allow automatic phasing and model building, and reveal alternate conformations that reflect the structure of proteins at room temperature.
		+
		+	Native SAD phasing at room temperature.,Greisman JB, Dalton KM, Sheehan CJ, Klureza MA, Kurinov I, Hekstra DR Acta Crystallogr D Struct Biol. 2022 Aug 1;78(Pt 8):986-996. doi:, 10.1107/S2059798322006799. Epub 2022 Jul 27. PMID:35916223<ref>PMID:35916223</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7l84" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 04:58, 3 August 2022

OCA — Wed, 03 Aug 2022 04:58:52 GMT

←Older revision		Revision as of 04:58, 3 August 2022
Line 3:		Line 3:
	<StructureSection load='7l84' size='340' side='right'caption='[[7l84]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='7l84' size='340' side='right'caption='[[7l84]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7l84]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L84 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=7L84 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7l84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L84 FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7l84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l84 OCA], [~~http~~://pdbe.org/7l84 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7l84 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7l84 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7l84 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l84 OCA], [https://pdbe.org/7l84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l84 RCSB], [https://www.ebi.ac.uk/pdbsum/7l84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l84 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>	+	[[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
		+
		+	==See Also==
		+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:57, 20 January 2021

OCA — Wed, 20 Jan 2021 05:57:07 GMT

←Older revision		Revision as of 05:57, 20 January 2021
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7l84 is ~~ON HOLD~~	+	==Hen Egg White Lysozyme by Native S-SAD at Room Temperature==
-		+	<StructureSection load='7l84' size='340' side='right'caption='[[7l84]], [[Resolution\|resolution]] 1.70Å' scene=''>
-	~~Authors~~: ~~Greisman~~, J.B., ~~Dalton~~, K.M., ~~Hekstra~~, D.R.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7l84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L84 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7L84 FirstGlance]. <br>
-	~~Description~~: ~~Hen Egg White Lysozyme by Native S~~-~~SAD at Room Temperature~~	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7l84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l84 OCA], [http://pdbe.org/7l84 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7l84 RCSB], [http://www.ebi.ac.uk/pdbsum/7l84 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7l84 ProSAT]</span></td></tr>
-	[[Category: ~~Hekstra~~, ~~D.R~~]]	+	</table>
-	[[Category: Greisman, J.B]]	+	== Function ==
-	[[Category: ~~Dalton~~, ~~K.M~~]]	+	[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Gallus gallus]]
		+	[[Category: Large Structures]]
		+	[[Category: Lysozyme]]
		+	[[Category: Dalton, K M]]
		+	[[Category: Greisman, J B]]
		+	[[Category: Hekstra, D R]]
		+	[[Category: Hydrolase]]

OCA: Protected "7l84" [edit=sysop:move=sysop]

OCA — Wed, 06 Jan 2021 05:56:49 GMT

Protected "7l84" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:56, 6 January 2021

OCA: New page: '''Unreleased structure''' The entry 7l84 is ON HOLD Authors: Greisman, J.B., Dalton, K.M., Hekstra, D.R. Description: Hen Egg White Lysozyme by Native S-SAD at Room Temperature [[Cate...

OCA — Wed, 06 Jan 2021 05:56:45 GMT

New page: '''Unreleased structure''' The entry 7l84 is ON HOLD Authors: Greisman, J.B., Dalton, K.M., Hekstra, D.R. Description: Hen Egg White Lysozyme by Native S-SAD at Room Temperature [[Cate...

New page

'''Unreleased structure'''

The entry 7l84 is ON HOLD

Authors: Greisman, J.B., Dalton, K.M., Hekstra, D.R.

Description: Hen Egg White Lysozyme by Native S-SAD at Room Temperature
[[Category: Unreleased Structures]]
[[Category: Hekstra, D.R]]
[[Category: Greisman, J.B]]
[[Category: Dalton, K.M]]