7lhg - Revision history

OCA at 19:37, 29 May 2024

OCA — Wed, 29 May 2024 19:37:52 GMT

←Older revision		Revision as of 19:37, 29 May 2024
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-	====	+	==Cryo-EM structure of E. coli P pilus tip assembly intermediate PapC-PapD-PapK-PapG in the first conformation==
-	<StructureSection load='7lhg' size='340' side='right'caption='[[7lhg]]' scene=''>	+	<StructureSection load='7lhg' size='340' side='right'caption='[[7lhg]], [[Resolution\|resolution]] 3.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7lhg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LHG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lhg OCA], [https://pdbe.org/7lhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lhg RCSB], [https://www.ebi.ac.uk/pdbsum/7lhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lhg ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.8Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lhg OCA], [https://pdbe.org/7lhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lhg RCSB], [https://www.ebi.ac.uk/pdbsum/7lhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lhg ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PAPC_ECOLX PAPC_ECOLX] Involved in the export and assembly of pili subunits across the outer membrane. Forms a hexameric ring-shaped pore in the outer bacterial membrane. The 2 nanometer-diameter pore allows the passage of the thin tip fibrillum. As for the rod, it probably unwinds into linear fibers which would therefore be narrow enough to pass through the pore.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Uropathogenic Escherichia coli assemble surface structures termed pili or fimbriae to initiate infection of the urinary tract. P pili facilitate bacterial colonization of the kidney and pyelonephritis. P pili are assembled through the conserved chaperone-usher pathway. Much of the structural and functional understanding of the chaperone-usher pathway has been gained through investigations of type 1 pili, which promote binding to the bladder and cystitis. In contrast, the structural basis for P pilus biogenesis at the usher has remained elusive. This is in part due to the flexible and variable-length P pilus tip fiber, creating structural heterogeneity, and difficulties isolating stable P pilus assembly intermediates. Here, we circumvent these hindrances and determine cryo-electron microscopy structures of the activated PapC usher in the process of secreting two- and three-subunit P pilus assembly intermediates, revealing processive steps in P pilus biogenesis and capturing new conformational dynamics of the usher assembly machine.
		+
		+	Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis.,Du M, Yuan Z, Werneburg GT, Henderson NS, Chauhan H, Kovach A, Zhao G, Johl J, Li H, Thanassi DG Nat Commun. 2021 Sep 1;12(1):5207. doi: 10.1038/s41467-021-25522-6. PMID:34471127<ref>PMID:34471127</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7lhg" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Adhesin 3D structures\|Adhesin 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Z~~-disk~~]]	+	[[Category: Chauhan H]]
		+	[[Category: Du M]]
		+	[[Category: Henderson N]]
		+	[[Category: Johl J]]
		+	[[Category: Kovach A]]
		+	[[Category: Li H]]
		+	[[Category: Thanassi D]]
		+	[[Category: Werneburg G]]
		+	[[Category: Yuan Z]]
		+	[[Category: Zhao G]]

OCA at 06:07, 11 August 2021

OCA — Wed, 11 Aug 2021 06:07:10 GMT

←Older revision		Revision as of 06:07, 11 August 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7lhg ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='7lhg' size='340' side='right'caption='[[7lhg]]' scene=''>
-	~~Authors~~: ~~Du, M~~.~~, Yuan, Z~~.~~, Werneburg, G~~.~~, Henderson, N~~.~~, Chauhan, H~~.~~, Kovach, A~~.~~, Zhao, G~~.~~, Johl, J~~.~~, Li, H~~., ~~Thanassi, D.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~: ~~Cryo-EM structure of E~~. ~~coli P pilus tip assembly intermediate PapC~~-~~PapD-PapK-PapG in the first conformation~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lhg OCA], [https://pdbe.org/7lhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lhg RCSB], [https://www.ebi.ac.uk/pdbsum/7lhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lhg ProSAT]</span></td></tr>
-	~~[[Category: Unreleased Structures~~]]	+	</table>
-	~~[[Category: Li~~, ~~H]]~~	+	__TOC__
-	[~~[Category~~: ~~Werneburg, G~~]]	+	</StructureSection>
-	~~[[Category: Du~~, ~~M]]~~	+	[[Category: Large Structures]]
-	[~~[Category~~: ~~Kovach, A~~]]	+	[[Category: Z-disk]]
-	~~[[Category: Chauhan~~, ~~H]]~~	+
-	[~~[Category~~: ~~Johl, J~~]]	+
-	~~[[Category: Yuan~~, ~~Z]]~~	+
-	[~~[Category~~: ~~Thanassi, D]~~]	+
-	[[Category: ~~Zhao, G~~]]	+
-	[[Category: ~~Henderson, N~~]]	+

OCA at 05:37, 24 February 2021

OCA — Wed, 24 Feb 2021 05:37:39 GMT

←Older revision		Revision as of 05:37, 24 February 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7lhg is ON HOLD	+	The entry 7lhg is ON HOLD until Paper Publication

	Authors: Du, M., Yuan, Z., Werneburg, G., Henderson, N., Chauhan, H., Kovach, A., Zhao, G., Johl, J., Li, H., Thanassi, D.		Authors: Du, M., Yuan, Z., Werneburg, G., Henderson, N., Chauhan, H., Kovach, A., Zhao, G., Johl, J., Li, H., Thanassi, D.
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	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Li, H]]		[[Category: Li, H]]
-	[[Category: Yuan, Z]]
	[[Category: Werneburg, G]]		[[Category: Werneburg, G]]
	[[Category: Du, M]]		[[Category: Du, M]]
-	[[Category: Thanassi, D]]
-	[[Category: Zhao, G]]
	[[Category: Kovach, A]]		[[Category: Kovach, A]]
	[[Category: Chauhan, H]]		[[Category: Chauhan, H]]
-	[[Category: Henderson, N]]
	[[Category: Johl, J]]		[[Category: Johl, J]]
		+	[[Category: Yuan, Z]]
		+	[[Category: Thanassi, D]]
		+	[[Category: Zhao, G]]
		+	[[Category: Henderson, N]]

OCA: Protected "7lhg" [edit=sysop:move=sysop]

OCA — Wed, 03 Feb 2021 09:28:38 GMT

Protected "7lhg" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:28, 3 February 2021

OCA: New page: '''Unreleased structure''' The entry 7lhg is ON HOLD Authors: Du, M., Yuan, Z., Werneburg, G., Henderson, N., Chauhan, H., Kovach, A., Zhao, G., Johl, J., Li, H., Thanassi, D. Descript...

OCA — Wed, 03 Feb 2021 09:28:36 GMT

New page: '''Unreleased structure''' The entry 7lhg is ON HOLD Authors: Du, M., Yuan, Z., Werneburg, G., Henderson, N., Chauhan, H., Kovach, A., Zhao, G., Johl, J., Li, H., Thanassi, D. Descript...

New page

'''Unreleased structure'''

The entry 7lhg is ON HOLD

Authors: Du, M., Yuan, Z., Werneburg, G., Henderson, N., Chauhan, H., Kovach, A., Zhao, G., Johl, J., Li, H., Thanassi, D.

Description: Cryo-EM structure of E. coli P pilus tip assembly intermediate PapC-PapD-PapK-PapG in the first conformation
[[Category: Unreleased Structures]]
[[Category: Li, H]]
[[Category: Yuan, Z]]
[[Category: Werneburg, G]]
[[Category: Du, M]]
[[Category: Thanassi, D]]
[[Category: Zhao, G]]
[[Category: Kovach, A]]
[[Category: Chauhan, H]]
[[Category: Henderson, N]]
[[Category: Johl, J]]