7lns - Revision history

OCA at 11:15, 14 June 2023

OCA — Wed, 14 Jun 2023 11:15:22 GMT

←Older revision		Revision as of 11:15, 14 June 2023
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	==NMR solution structure of PsDef2 defensin from P. sylvestris==		==NMR solution structure of PsDef2 defensin from P. sylvestris==
-	<StructureSection load='7lns' size='340' side='right'caption='[[7lns~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='7lns' size='340' side='right'caption='[[7lns]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7lns]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LNS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7lns]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pinus_sylvestris Pinus sylvestris]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LNS FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lns OCA], [https://pdbe.org/7lns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lns RCSB], [https://www.ebi.ac.uk/pdbsum/7lns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lns ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lns OCA], [https://pdbe.org/7lns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lns RCSB], [https://www.ebi.ac.uk/pdbsum/7lns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lns ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DEF2_PINSY DEF2_PINSY]] Plant defense peptide. Has antifungal activity.[UniProtKB:A4L7R7]	+	[https://www.uniprot.org/uniprot/DEF2_PINSY DEF2_PINSY] Plant defense peptide. Has antifungal activity.[UniProtKB:A4L7R7]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 7lns" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 7lns" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Defensin 3D structures\|Defensin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 22:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Hrunyk, N I~~]]	+	[[Category: Pinus sylvestris]]
-	[[Category: ~~Kovaleva, V~~]]	+	[[Category: Hrunyk NI]]
-	[[Category: ~~Nesmelova, I~~ V]]	+	[[Category: Kovaleva V]]
-	[[Category: ~~Shalovylo, Y I~~]]	+	[[Category: Nesmelova IV]]
-	[[Category: ~~Yusypovych, Y M~~]]	+	[[Category: Shalovylo YI]]
-	[[Category: ~~Antibacterial protein]]~~	+	[[Category: Yusypovych YM]]
-	~~[[Category: Antifungal protein]]~~	+
-	~~[[Category: Plant protein~~]]	+

OCA at 10:32, 6 April 2022

OCA — Wed, 06 Apr 2022 10:32:38 GMT

←Older revision		Revision as of 10:32, 6 April 2022
Line 1:		Line 1:

	==NMR solution structure of PsDef2 defensin from P. sylvestris==		==NMR solution structure of PsDef2 defensin from P. sylvestris==
-	<StructureSection load='7lns' size='340' side='right'caption='[[7lns]]' scene=''>	+	<StructureSection load='7lns' size='340' side='right'caption='[[7lns]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LNS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7lns]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LNS FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lns OCA], [https://pdbe.org/7lns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lns RCSB], [https://www.ebi.ac.uk/pdbsum/7lns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lns ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lns OCA], [https://pdbe.org/7lns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lns RCSB], [https://www.ebi.ac.uk/pdbsum/7lns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lns ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/DEF2_PINSY DEF2_PINSY]] Plant defense peptide. Has antifungal activity.[UniProtKB:A4L7R7]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Plant defensins demonstrate high structural stability at extreme temperatures and pH values and, in general, are non-toxic to mammalian cells. These properties make them attractive candidates for use in biotechnology and biomedicine. Knowing the structure-function relationship is desirable to guide the design of plant defensin-based applications. Thus far, the broad range of biological activities was described only for one defensin from gymnosperms, the defensin PsDef1 from Scots pine. Here, we report that closely related defensin from the same taxonomy group, PsDef2, differing from PsDef1 by six amino acids, also possesses antimicrobial, antibacterial, and insect alpha-amylase inhibitory activities. We also report the solution structure and dynamics properties of PsDef2 assessed using a combination of experimental nuclear magnetic resonance (NMR) techniques. Lastly, we perform a comparative analysis of PsDef2 and PsDef1 gaining a molecular-level insight into their structure-dynamics-function relationship.
		+
		+	Structure, dynamics, and function of PsDef2 defensin from Pinus sylvestris.,Bukhteeva I, Hrunyk NI, Yusypovych YM, Shalovylo YI, Kovaleva V, Nesmelova IV Structure. 2022 Mar 15. pii: S0969-2126(22)00082-X. doi:, 10.1016/j.str.2022.03.001. PMID:35334207<ref>PMID:35334207</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7lns" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hrunyk NI]]	+	[[Category: Hrunyk, N I]]
-	[[Category: Kovaleva V]]	+	[[Category: Kovaleva, V]]
-	[[Category: Nesmelova IV]]	+	[[Category: Nesmelova, I V]]
-	[[Category: Shalovylo YI]]	+	[[Category: Shalovylo, Y I]]
-	[[Category: Yusypovych YM]]	+	[[Category: Yusypovych, Y M]]
		+	[[Category: Antibacterial protein]]
		+	[[Category: Antifungal protein]]
		+	[[Category: Plant protein]]

OCA at 10:44, 30 March 2022

OCA — Wed, 30 Mar 2022 10:44:46 GMT

←Older revision		Revision as of 10:44, 30 March 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7lns ~~is ON HOLD until Paper Publication~~	+	==NMR solution structure of PsDef2 defensin from P. sylvestris==
-		+	<StructureSection load='7lns' size='340' side='right'caption='[[7lns]]' scene=''>
-	~~Authors~~: ~~Nesmelova, I~~.V., ~~Kovaleva~~, V., ~~Hrunyk, N~~.I., ~~Yusypovych, Y~~.M., ~~Shalovylo, Y~~.I.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LNS FirstGlance]. <br>
-	~~Description: NMR solution structure of PsDef2 defensin from P. sylvestris~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lns OCA], [https://pdbe.org/7lns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lns RCSB], [https://www.ebi.ac.uk/pdbsum/7lns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lns ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Nesmelova, I.V~~]]	+	__TOC__
-	[[Category: ~~Yusypovych, Y.M~~]]	+	</StructureSection>
-	[[Category: ~~Kovaleva, V~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Hrunyk, N.I~~]]	+	[[Category: Hrunyk NI]]
-	[[Category: ~~Shalovylo, Y.I~~]]	+	[[Category: Kovaleva V]]
		+	[[Category: Nesmelova IV]]
		+	[[Category: Shalovylo YI]]
		+	[[Category: Yusypovych YM]]

OCA at 08:06, 15 September 2021

OCA — Wed, 15 Sep 2021 08:06:35 GMT

←Older revision		Revision as of 08:06, 15 September 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7lns is ON HOLD	+	The entry 7lns is ON HOLD until Paper Publication

	Authors: Nesmelova, I.V., Kovaleva, V., Hrunyk, N.I., Yusypovych, Y.M., Shalovylo, Y.I.		Authors: Nesmelova, I.V., Kovaleva, V., Hrunyk, N.I., Yusypovych, Y.M., Shalovylo, Y.I.

OCA at 04:57, 18 August 2021

OCA — Wed, 18 Aug 2021 04:57:08 GMT

←Older revision		Revision as of 04:57, 18 August 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7lns is ON HOLD ~~until Paper Publication~~	+	The entry 7lns is ON HOLD

	Authors: Nesmelova, I.V., Kovaleva, V., Hrunyk, N.I., Yusypovych, Y.M., Shalovylo, Y.I.		Authors: Nesmelova, I.V., Kovaleva, V., Hrunyk, N.I., Yusypovych, Y.M., Shalovylo, Y.I.

OCA at 05:38, 24 February 2021

OCA — Wed, 24 Feb 2021 05:38:52 GMT

←Older revision		Revision as of 05:38, 24 February 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7lns is ON HOLD	+	The entry 7lns is ON HOLD until Paper Publication

	Authors: Nesmelova, I.V., Kovaleva, V., Hrunyk, N.I., Yusypovych, Y.M., Shalovylo, Y.I.		Authors: Nesmelova, I.V., Kovaleva, V., Hrunyk, N.I., Yusypovych, Y.M., Shalovylo, Y.I.

OCA: Protected "7lns" [edit=sysop:move=sysop]

OCA — Wed, 17 Feb 2021 08:47:44 GMT

Protected "7lns" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:47, 17 February 2021

OCA: New page: '''Unreleased structure''' The entry 7lns is ON HOLD Authors: Nesmelova, I.V., Kovaleva, V., Hrunyk, N.I., Yusypovych, Y.M., Shalovylo, Y.I. Description: NMR solution structure of PsDe...

OCA — Wed, 17 Feb 2021 08:47:43 GMT

New page: '''Unreleased structure''' The entry 7lns is ON HOLD Authors: Nesmelova, I.V., Kovaleva, V., Hrunyk, N.I., Yusypovych, Y.M., Shalovylo, Y.I. Description: NMR solution structure of PsDe...

New page

'''Unreleased structure'''

The entry 7lns is ON HOLD

Authors: Nesmelova, I.V., Kovaleva, V., Hrunyk, N.I., Yusypovych, Y.M., Shalovylo, Y.I.

Description: NMR solution structure of PsDef2 defensin from P. sylvestris
[[Category: Unreleased Structures]]
[[Category: Nesmelova, I.V]]
[[Category: Yusypovych, Y.M]]
[[Category: Kovaleva, V]]
[[Category: Hrunyk, N.I]]
[[Category: Shalovylo, Y.I]]