7mcj - Revision history

OCA at 16:09, 18 October 2023

OCA — Wed, 18 Oct 2023 16:09:16 GMT

←Older revision		Revision as of 16:09, 18 October 2023
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	<StructureSection load='7mcj' size='340' side='right'caption='[[7mcj]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='7mcj' size='340' side='right'caption='[[7mcj]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7mcj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MCJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7mcj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MCJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FD7:N-(2,6-diethylphenyl)-N-(N-ethylcarbamimidoyl)urea'>FD7</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7l9u\|7l9u]], [[7lxi\|7lxi]]</div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FD7:N-(2,6-diethylphenyl)-N-(N-ethylcarbamimidoyl)urea'>FD7</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mcj OCA], [https://pdbe.org/7mcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mcj RCSB], [https://www.ebi.ac.uk/pdbsum/7mcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mcj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mcj OCA], [https://pdbe.org/7mcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mcj RCSB], [https://www.ebi.ac.uk/pdbsum/7mcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mcj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/UMAA_MYCTU UMAA_MYCTU]] Methyltransferase that modifies short-chain fatty acids. In vitro, catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (SAM) to the double bond of phospholipid-linked oleic acid to produce tuberculostearic acid (10-methylstearic-acid or TSA).<ref>PMID:23435098</ref>	+	[https://www.uniprot.org/uniprot/UMAA_MYCTU UMAA_MYCTU] Methyltransferase that modifies short-chain fatty acids. In vitro, catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (SAM) to the double bond of phospholipid-linked oleic acid to produce tuberculostearic acid (10-methylstearic-acid or TSA).<ref>PMID:23435098</ref>
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Structural genomic]]~~	+	[[Category: Mycobacterium tuberculosis H37Rv]]
-	~~[[Category: Compound 8918]]~~	+
-	~~[[Category: Short-chain fatty acid modification]]~~	+
-	~~[[Category: Ssgcid]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 13:04, 4 May 2022

OCA — Wed, 04 May 2022 13:04:37 GMT

←Older revision		Revision as of 13:04, 4 May 2022
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	==Crystal Structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with compound 8918==		==Crystal Structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with compound 8918==
-	<StructureSection load='7mcj' size='340' side='right'caption='[[7mcj]]' scene=''>	+	<StructureSection load='7mcj' size='340' side='right'caption='[[7mcj]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MCJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7mcj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MCJ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mcj OCA], [https://pdbe.org/7mcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mcj RCSB], [https://www.ebi.ac.uk/pdbsum/7mcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mcj ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FD7:N-(2,6-diethylphenyl)-N-(N-ethylcarbamimidoyl)urea'>FD7</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7l9u\|7l9u]], [[7lxi\|7lxi]]</div></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mcj OCA], [https://pdbe.org/7mcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mcj RCSB], [https://www.ebi.ac.uk/pdbsum/7mcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mcj ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/UMAA_MYCTU UMAA_MYCTU]] Methyltransferase that modifies short-chain fatty acids. In vitro, catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (SAM) to the double bond of phospholipid-linked oleic acid to produce tuberculostearic acid (10-methylstearic-acid or TSA).<ref>PMID:23435098</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Structural genomic]]
		+	[[Category: Compound 8918]]
		+	[[Category: Short-chain fatty acid modification]]
		+	[[Category: Ssgcid]]
		+	[[Category: Transferase]]

OCA at 09:45, 13 April 2022

OCA — Wed, 13 Apr 2022 09:45:08 GMT

←Older revision		Revision as of 09:45, 13 April 2022
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-	'''Unreleased structure'''

-	~~The entry 7mcj is ON HOLD until Paper Publication~~	+	==Crystal Structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with compound 8918==
-		+	<StructureSection load='7mcj' size='340' side='right'caption='[[7mcj]]' scene=''>
-	~~Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MCJ FirstGlance]. <br>
-	~~Description:~~ Crystal Structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with compound 8918	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mcj OCA], [https://pdbe.org/7mcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mcj RCSB], [https://www.ebi.ac.uk/pdbsum/7mcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mcj ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[Category: ~~Seattle Structural Genomics Center For Infectious Disease (Ssgcid)~~]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]

OCA: Protected "7mcj" [edit=sysop:move=sysop]

OCA — Wed, 14 Apr 2021 05:40:20 GMT

Protected "7mcj" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:40, 14 April 2021

OCA: New page: '''Unreleased structure''' The entry 7mcj is ON HOLD until Paper Publication Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Description: Crystal Structure ...

OCA — Wed, 14 Apr 2021 05:40:19 GMT

New page: '''Unreleased structure''' The entry 7mcj is ON HOLD until Paper Publication Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Description: Crystal Structure ...

New page

'''Unreleased structure'''

The entry 7mcj is ON HOLD until Paper Publication

Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Description: Crystal Structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with compound 8918
[[Category: Unreleased Structures]]
[[Category: Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]